Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jiacheng Bi"'
Autor:
Yao Liu, Zhongliang Li, Xiaoguang Zhao, Jing Xiao, Jiacheng Bi, Xian-Yang Li, Guokai Chen, Ligong Lu
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract The ATP-adenosine pathway has emerged as a promising target for cancer therapy, but challenges remain in achieving effective tumor control. Early research focused on blocking the adenosine generating enzyme CD73 and the adenosine receptors A
Externí odkaz:
https://doaj.org/article/8c568c00c55e4cf8b7b3d656ba2af344
Autor:
Jiacheng Bi, Xiaomeng Jin, Chaoyue Zheng, Chen Huang, Chao Zhong, Xiaohu Zheng, Zhigang Tian, Haoyu Sun
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Natural killer (NK) cells not only are innate effector lymphocytes that directly participate in tumor surveillance but are also essential helpers in the antitumor CD8+ T‐cell response. However, the molecular mechanisms and potential checkp
Externí odkaz:
https://doaj.org/article/f0b800eb887a42aa9430f6c0e5d47626
Autor:
Zhigang Tian, Xiaohu Zheng, Yingying Huang, Jiacheng Bi, Xiaomeng Jin, Chaoyue Zheng, Haoyu Sun
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background To enhance the efficacy of adoptive NK cell therapy against solid tumors, NK cells must be modified to resist exhaustion in the tumor microenvironment (TME). However, the molecular checkpoint underlying NK cell exhaustion in the TME remain
Externí odkaz:
https://doaj.org/article/00308cc36a3045c1829835d3321c545d
Autor:
Xiaomeng Jin, Jiacheng Bi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Effective and long-term treatment is required for controlling chronic Hepatitis B Virus (HBV) infection. Natural killer (NK) cells are antiviral innate lymphocytes and represent an essential arm of current immunotherapy. In chronic HBV (CHB), NK cell
Externí odkaz:
https://doaj.org/article/ce8ac24d28ca4d23adcabfc55ce77846
Autor:
Chen Huang, Jiacheng Bi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are cytotoxic innate lymphocytes that play an important role in immune surveillance. The development, maturation and effector functions of NK cells are orchestrated by the T-box transcription factor T-bet, whose expression i
Externí odkaz:
https://doaj.org/article/3340c9dc60cc43df9d3b637524239518
Autor:
Shuxin Yang, Wenjuan Zhao, Muchun Zhu, Huijuan Hu, Weijie Wang, Zhongsheng Zang, Meiling Jin, Jiacheng Bi, Jiandong Huang, Chenli Liu, Xuefei Li, Peng Yin, Nan Li
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The engineered “obligate” anaerobic Salmonella typhimurium strain YB1 shows a prominent ability to repress tumor growth and metastasis, which has great potential as a novel cancer immunotherapy. However, the antitumor mechanism of YB1 remains une
Externí odkaz:
https://doaj.org/article/3c577d489c384a049bfffc320cd6b3f3
Autor:
Lukman O. Afolabi, Jiacheng Bi, Xuguang Li, Adeleye O. Adeshakin, Funmilayo O. Adeshakin, Haisi Wu, Dehong Yan, Liang Chen, Xiaochun Wan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Histone deacetylases (HDAC) are frequently overexpressed in tumors, and their inhibition has shown promising anti-tumor effects. However, the synergistic effects of HDAC inhibition with immune cell therapy have not been fully explored. Natural killer
Externí odkaz:
https://doaj.org/article/533ba0fb59ce44d299f581ecb9b254ec
Autor:
Jiacheng Bi, Xuefu Wang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Natural killer (NK) cells are innate lymphocytes specialized in immune surveillance against tumors and infections. To reach their optimal functional status, NK cells must undergo a process of maturation from immature to mature NK cells. Genetically m
Externí odkaz:
https://doaj.org/article/499656a6aebd40669b97415d4521f5a9
Publikováno v:
PeerJ, Vol 7, p e7525 (2019)
Afforestation is a key approach used to effectively prevent ecosystem degradation, which in itself is a key reason for the obstruction of sustainable societal development. In order to suppress sand and dust storms as a result of ecological environmen
Externí odkaz:
https://doaj.org/article/cf5484179d8a4b828a5ea34964970a67
Autor:
Jiacheng Bi, Zhigang Tian
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
NK cells play important roles in the innate immune responses against tumors. The effector function of NK cells relies on the integration of activating and inhibitory signals. Emerging checkpoint receptors and molecules are being revealed to mediate N
Externí odkaz:
https://doaj.org/article/47c89d1f062143d59b222b5219f72b09