Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jia-li Pu"'
Autor:
Si-Si Jiang, Yi-Ling Wang, Qiu-Han Xu, Lu-Yan Gu, Rui-Qing Kang, Wen-Yi Yang, Bao-Rong Zhang, Jun Tian, Jia-Li Pu
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Peripheral immune cells play a vital role in the development of Parkinson’s disease (PD). However, their cytokine and chemokine secretion functions remain unclear. Therefore, we aimed to explore the cytokine and chemokine secretion functio
Externí odkaz:
https://doaj.org/article/f138d6060e7c4b7294c3d66c184df774
Autor:
Ting Shen, Jia-Li Pu, Ya-Si Jiang, Yu-Mei Yue, Ting-Ting He, Bo-Yi Qu, Shuai Zhao, Ya-Ping Yan, Hsin-Yi Lai, Bao-Rong Zhang
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1154-1160 (2023)
Multiple single nucleotide polymorphisms may contribute to cognitive decline in Parkinson’s disease. However, the mechanism by which these single nucleotide polymorphisms modify brain imaging phenotype remains unclear. The aim of this study was to
Externí odkaz:
https://doaj.org/article/00cddb63b0cd4e5cbd8388ce1b393c70
Autor:
Jun Tian, Shao-Bing Dai, Si-Si Jiang, Wen-Yi Yang, Yi-Qun Yan, Zhi-Hao Lin, Jia-Xian Dong, Yi Liu, Ran Zheng, Ying Chen, Bao-Rong Zhang, Jia-Li Pu
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Recent evidence suggests that innate and adaptive immunity play a crucial role in Parkinson’s disease (PD). However, studies regarding specific immune cell classification in the peripheral blood in PD remain lacking. Therefore, we aimed to
Externí odkaz:
https://doaj.org/article/2827508c733f441aa85b2c6745fcdaa6
Autor:
Xiao-Jun Guan, Tao Guo, Cheng Zhou, Ting Gao, Jing-Jing Wu, Victor Han, Steven Cao, Hong-Jiang Wei, Yu-Yao Zhang, Min Xuan, Quan-Quan Gu, Pei-Yu Huang, Chun-Lei Liu, Jia-Li Pu, Bao-Rong Zhang, Feng Cui, Xiao-Jun Xu, Min-Ming Zhang
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2743-2749 (2022)
Brain radiomics can reflect the characteristics of brain pathophysiology. However, the value of T1-weighted images, quantitative susceptibility mapping, and R2* mapping in the diagnosis of Parkinson’s disease (PD) was underestimated in previous stu
Externí odkaz:
https://doaj.org/article/df44762f656b4523ac337b409ea15681
Autor:
Zhong-Xuan Wang, Yi Liu, Yao-Lin Li, Qiao Wei, Rong-Rong Lin, Ruiqing Kang, Yang Ruan, Zhi-Hao Lin, Nai-Jia Xue, Bao-Rong Zhang, Jia-Li Pu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8651 (2023)
DNA damage and defective DNA repair are extensively linked to neurodegeneration in Parkinson’s disease (PD), but the underlying molecular mechanisms remain poorly understood. Here, we determined that the PD-associated protein DJ-1 plays an essentia
Externí odkaz:
https://doaj.org/article/2ebee24eb18d476caf9b67c30d82f5e4
Autor:
Chong-Yao Jin, Ran Zheng, Zhi-Hao Lin, Nai-Jia Xue, Ying Chen, Ting Gao, Yi-Qun Yan, Yi Fang, Ya-Ping Yan, Xin-Zhen Yin, Jun Tian, Jia-Li Pu, Bao-Rong Zhang
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background To date, the genetic contribution to Parkinson’s disease (PD) remains unclear. Mutations in the collagen type VI alpha 3 (COL6A3) gene were recently identified as a cause of isolated dystonia. Since PD and dystonia are closely r
Externí odkaz:
https://doaj.org/article/91c89c30e7af4b629c7fccd8877e61c6
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6313 (2023)
Parkinson’s disease (PD) is the second most common neurodegenerative disease around the world; however, its pathogenesis remains unclear so far. Recent advances have shown that DNA damage and repair deficiency play an important role in the pathophy
Externí odkaz:
https://doaj.org/article/6b2ca4595925417398e76162a88c53fb
Autor:
Wen-Yi Yang, Si-Si Jiang, Jia-Li Pu, Chong-Yao Jin, Ting Gao, Ran Zheng, Jun Tian, Bao-Rong Zhang
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
BackgroundParkinson's disease (PD) and dystonia are closely related in terms of pathophysiology and clinical manifestations, but their common genetic characteristics remain unclear. Some genome-wide association studies (GWASs) and replication studies
Externí odkaz:
https://doaj.org/article/62babbbb34554f4ebedeae613bb2de3f
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 3, Pp 501-505 (2019)
Differentiation of human fibroblasts into functional neurons depends on the introduction of viral-mediated transcription factors, which present risks of viral gene integration and tumorigenicity. In recent years, although some studies have been succe
Externí odkaz:
https://doaj.org/article/b6dd437945234c55839873bd05c1023c
Autor:
Jia-Li Pu, Ting Gao, Xiao-Li Si, Ran Zheng, Chong-Yao Jin, Yang Ruan, Yi Fang, Ying Chen, Zhe Song, Xin-Zhen Yin, Ya-Ping Yan, Jun Tian, Bao-Rong Zhang
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
IntroductionMutations in the teneurin transmembrane protein 4 (TENM4) gene, known to be involved in neuropsychiatric disorders, have been identified in three pedigree of essential tremor (ET) from Spain. ET has overlapping clinical manifestations and
Externí odkaz:
https://doaj.org/article/928b9c32e45845e989c833df6dd28318