Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Jia-jia ZHANG"'
Autor:
Alireza Ghanbarpour, Steven E. Cohen, Xue Fei, Laurel F. Kinman, Tristan A. Bell, Jia Jia Zhang, Tania A. Baker, Joseph H. Davis, Robert T. Sauer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract AAA+ proteases degrade intracellular proteins in a highly specific manner. E. coli ClpXP, for example, relies on a C-terminal ssrA tag or other terminal degron sequences to recognize proteins, which are then unfolded by ClpX and subsequently
Externí odkaz:
https://doaj.org/article/f72b46a348b247609e8481dbe950089a
Autor:
Jia-Jia Zhang, Chang-Geng Song, Miao Wang, Gai-Qin Zhang, Bin Wang, Xi Chen, Peng Lin, Yu-Meng Zhu, Zhi-Chuan Sun, Ya-Zhou Wang, Jian-Li Jiang, Ling Li, Xiang-Min Yang, Zhi-Nan Chen
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 10, Pp 1135-1152 (2023)
Morphine is a frequently used analgesic that activates the mu-opioid receptor (MOR), which has prominent side effects of tolerance. Although the inefficiency of morphine in inducing the endocytosis of MOR underlies the development of morphine toleran
Externí odkaz:
https://doaj.org/article/d68f464005ed4810b8ecc5b85b29dfcd
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Gynecological cancer is one of the most severe diseases that threaten the lives and health of women worldwide. Its incidence rate increases with each passing year and becomes more prevalent among young people. The prognosis of gynecological
Externí odkaz:
https://doaj.org/article/9e4425bc39084f6db12eb7657b94def7
Autor:
Hao Wang, Ruo-Fei Tian, Xue Liang, Jing Fan, Zi-Chuan Duan, Xin-Yu Fan, Jia-Jia Zhang, Dong-Sheng Yao, Zhi-Nan Chen, Ling Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Background and aimsPancreatic adenocarcinoma (PAAD) is highly aggressive and characterized by a poor prognosis. Oxidative stress has great impacts on the occurrence and development of tumors. However, the predictive role of oxidative stress related g
Externí odkaz:
https://doaj.org/article/c92cb23e9d1e4dc48f0e081ce9b41885
Autor:
Xin-peng XU, Ping HE, Li-min CHUAN, Xiao-yan LIU, Ying-xia LIU, Jia-jia ZHANG, Xiao-meng HUANG, Shao-jun QIU, Shi-cheng ZHAO, Wei ZHOU
Publikováno v:
Journal of Integrative Agriculture, Vol 20, Iss 10, Pp 2772-2780 (2021)
Quantification of currently attainable yield and fertilizer requirements can provide detailed information for assessing the food supply capacity and offer data support for agricultural decision-making. Datasets from a total of 5 408 field experiments
Externí odkaz:
https://doaj.org/article/3274ae4541d34dedad6dfd6e19677ea2
Autor:
Yu-Shui Ma, Ji-Bin Liu, Lan Lin, Hui Zhang, Jian-Jun Wu, Yi Shi, Cheng-You Jia, Dan-Dan Zhang, Fei Yu, Hui-Min Wang, Yu-Zhen Yin, Xiao-Hui Jiang, Pei-Yao Wang, Lin-Lin Tian, Ping-Sheng Cao, Xu-Ming Wu, Hai-Min Lu, Li-Peng Gu, Jia-Jia Zhang, Gu-Jun Cong, Pei Luo, Xiao-Ming Zhong, Bo Cai, Min-Xin Shi, Su-Qing Zhang, Liu Li, Wen-Jie Zhang, Yu Liu, Zhi-Zhen Li, Ting-Miao Wu, Zhi-Jun Wu, Gao-Ren Wang, Zhong-Wei Lv, Chang-Chun Ling, Kai-Jian Chu, Da Fu
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Hepatocellular carcinoma (HCC) is a heterogeneous tumor with an increased incidence worldwide accompanied by high mortality and dismal prognosis. Emerging evidence indicates that mesenchymal stem cells (MSCs)-derived exosomes possess protect
Externí odkaz:
https://doaj.org/article/6981ee02b88e4d75bd4b126f2e693ff0
Publikováno v:
MedComm, Vol 3, Iss 3, Pp n/a-n/a (2022)
Abstract Opioid abuse and addiction have become a global pandemic, posing tremendous health and social burdens. The rewarding effects and the occurrence of withdrawal symptoms are the two mainstays of opioid addiction. Mu‐opioid receptors (MORs), a
Externí odkaz:
https://doaj.org/article/a9f0aac651d54585882bb6aab5b96109
Autor:
Ji‐Min Dai, Xue‐Qin Zhang, Jia‐Jia Zhang, Wei‐Jie Yang, Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen
Publikováno v:
MedComm, Vol 3, Iss 2, Pp n/a-n/a (2022)
Abstract Systemic inflammatory response syndrome (SIRS) is characterized by dysregulated cytokine release, immune responses and is associated with organ dysfunction. IL‐6R blockade indicates promising therapeutic effects in cytokine release storm b
Externí odkaz:
https://doaj.org/article/154e0c7013a14c5390f5645635429187
Autor:
Yu-Shui Ma, Xiao-Feng Wang, Yun-Jie Zhang, Pei Luo, Hui-Deng Long, Liu Li, Hui-Qiong Yang, Ru-Ting Xie, Cheng-You Jia, Gai-Xia Lu, Zheng-Yan Chang, Jia-Jia Zhang, Shao-Bo Xue, Zhong-Wei Lv, Fei Yu, Qing Xia, Da Fu
Publikováno v:
Molecular Therapy: Oncolytics, Vol 16, Iss , Pp 147-157 (2020)
Functional elimination of p53 is a common feature of a large percentage of human malignancies. Here, we report the development of a pharmacological strategy aimed at restoring p53 function and its use for targeted therapy in p53-deficient mice. Speci
Externí odkaz:
https://doaj.org/article/19e5d6bc50b64885983f3238c6b01f1b
Autor:
Jia-Jia Zhang, Long-Long Sun, Ya-Nan Wang, Gui-Ying Xie, Shi-Heng An, Wen-Bo Chen, Qing-Bo Tang, Xin-Cheng Zhao
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
The fall armyworm Spodoptera frugiperda (S. frugiperda) (Lepidoptera: Noctuidae) is a worldwide, disruptive, agricultural pest species. The larvae of S. frugiperda feed on seedling, leave, and kernel of crops with chewing mouthparts, resulting in red
Externí odkaz:
https://doaj.org/article/9b6f07d673d24902a0a2bf3c1d560eb5