Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jia-Wen Shou"'
Autor:
Jia-Wen Shou, Pang-Chui Shaw
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11600 (2023)
Obesity is defined as a dampness-heat syndrome in traditional Chinese medicine. Coptidis Rhizoma is an herb used to clear heat and eliminate dampness in obesity and its complications. Berberine (BBR), the main active compound in Coptidis Rhizoma, sho
Externí odkaz:
https://doaj.org/article/337f84acb03749859cf8994c68eaa9c7
Autor:
Yan Wang, Qian Tong, Shu-Rong Ma, Zhen-Xiong Zhao, Li-Bin Pan, Lin Cong, Pei Han, Ran Peng, Hang Yu, Yuan Lin, Tian-Le Gao, Jia-Wen Shou, Xiao-Yang Li, Xian-Feng Zhang, Zheng-Wei Zhang, Jie Fu, Bao-Ying Wen, Jin-Bo Yu, Xuetao Cao, Jian-Dong Jiang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-20 (2021)
Abstract The phenylalanine–tyrosine–dopa–dopamine pathway provides dopamine to the brain. In this process, tyrosine hydroxylase (TH) is the rate-limiting enzyme that hydroxylates tyrosine and generates levodopa (l-dopa) with tetrahydrobiopterin
Externí odkaz:
https://doaj.org/article/678b44e28f764ee2b9cc1ea4d69df7da
Publikováno v:
Toxins, Vol 14, Iss 6, p 392 (2022)
VVA2 (volvatoxin A chain 2) is a cardiotoxic protein purified from Volvariella volvacea. Its biological activities include hemolysis, writhing reaction, neurotoxicity, and ventricular systolic arresting activity. The cytotoxicity of VVA2 was mainly c
Externí odkaz:
https://doaj.org/article/5c62f93c5da24c4e9278e8ef9c369334
Autor:
Jia-Wen Shou, Pang-Chui Shaw
Publikováno v:
Cells, Vol 11, Iss 5, p 796 (2022)
Neurological disorders are ranked as the leading cause of disability and the second leading cause of death worldwide, underscoring an urgent necessity to develop novel pharmacotherapies. Berberine (BBR) is a well-known phytochemical isolated from a n
Externí odkaz:
https://doaj.org/article/9a6d7b9e96e54f13a012749959be69ab
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Neurodegeneration is the loss of structure and/or function of neurons. Oxidative stress has been suggested as one of the common etiology in most of the neurodegenerative diseases. Previous studies have demonstrated the beneficial effects of berberine
Externí odkaz:
https://doaj.org/article/ac712240777c4ff493c32b510942b558
Autor:
Chi-Yu He, Jie Fu, Jing-Yi Ma, Ru Feng, Xiang-Shan Tan, Min Huang, Jia-Wen Shou, Zhen-Xiong Zhao, Xiao-Yang Li, Xian-Feng Zhang, Yangchao Chen, Yan Wang
Publikováno v:
Molecules, Vol 19, Iss 7, Pp 10291-10308 (2014)
Polygonum capitatum Buch.-Ham.ex D. Don, a traditional Miao-nationality herbal medicine, has been widely used in the treatment of various urologic disorders. Recent pharmacological studies demonstrated that a pure compound, FR429, isolated from the e
Externí odkaz:
https://doaj.org/article/e542a8773a834c81821909fc118650f1
Publikováno v:
Molecules, Vol 22, Iss 6, p 932 (2017)
Gut microbiota is populated with an immense number of microorganisms, which can be regulated by dietary components and drugs to markedly affect the nutritional and health status of the host. Eight medicinal isoquinoline alkaloids from natural plants
Externí odkaz:
https://doaj.org/article/e81f0ce534e64aeab7e9bee03e2db1f5
Autor:
Xiang-Shan Tan, Jing-Yi Ma, Ru Feng, Chao Ma, Wen-Jing Chen, Yu-Peng Sun, Jie Fu, Min Huang, Chi-Yu He, Jia-Wen Shou, Wen-Yi He, Yan Wang, Jian-Dong Jiang
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77969 (2013)
Berberine (BBR) has been confirmed to have multiple bioactivities in clinic, such as cholesterol-lowering, anti-diabetes, cardiovascular protection and anti- inflammation. However, BBR's plasma level is very low; it cannot explain its pharmacological
Externí odkaz:
https://doaj.org/article/00e78cfc51ab463cb867e9949a11771b
Autor:
Jing-Yi Ma, Xuelin Zhou, Jie Fu, Chi-Yu He, Ru Feng, Min Huang, Jia-Wen Shou, Zhen-Xiong Zhao, Xiao-Yang Li, Luye Zhang, Yang-Chao Chen, Yan Wang
Publikováno v:
Molecules, Vol 21, Iss 9, p 1110 (2016)
Ellagitannin is a common compound in food and herbs, but there are few detailed studies on the metabolism of purified ellagitannins. FR429 is a purified ellagitannin with antitumor potential, which is from Polygonum capitatum Buch.-Ham.ex D. Don. The
Externí odkaz:
https://doaj.org/article/4264a245a870420983adeb773ba57752
Autor:
Jia-Wen Shou, Pang-Chui Shaw
Publikováno v:
Phytomedicine. 115:154842