Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jia-Ray Yu"'
Autor:
Thelma M. Escobar, Jia-Ray Yu, Sanxiong Liu, Kimberly Lucero, Nikita Vasilyev, Evgeny Nudler, Danny Reinberg
Publikováno v:
Science Advances. 8
The epigenetic process safeguards cell identity during cell division through the inheritance of appropriate gene expression profiles. We demonstrated previously that parental nucleosomes are inherited by the same chromatin domains during DNA replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1909216710f9b40522aa896edbfc5ed7
https://doi.org/10.1126/sciadv.abm3945
https://doi.org/10.1126/sciadv.abm3945
Autor:
Evgeny Nudler, Danny Reinberg, Kimberly Lucero, Jia Ray Yu, Nikita Vasilyev, Thelma M. Escobar, Sanxiong Liu
The epigenetic process safeguards cell identity during cell division through the inheritance of appropriate gene expression profiles. We demonstrated previously that parental nucleosomes are inherited by the same chromatin domains during DNA replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dbc6d5797155efb94035925ea331956
https://doi.org/10.1101/2021.08.31.458436
https://doi.org/10.1101/2021.08.31.458436
Autor:
Benjamin A. Garcia, Chul Hwan Lee, Gary LeRoy, Jeffrey Granat, Jia Ray Yu, Ricardo Saldaña-Meyer, Beatrix Ueberheide, Danny Reinberg, Peder J. Lund, Ying Jin, James M. Stafford, Joshua Andrade
Publikováno v:
Genes & Development. 33:1428-1440
The histone methyltransferase activity of PRC2 is central to the formation of H3K27me3-decorated facultative heterochromatin and gene silencing. In addition, PRC2 has been shown to automethylate its core subunits, EZH1/EZH2 and SUZ12. Here, we identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e625f2f6c034e807da3f628fab790d
https://doi.org/10.1101/gad.328773.119
https://doi.org/10.1101/gad.328773.119
Autor:
Escobar, Thelma M.1,2, Jia-Ray Yu1,2, Sanxiong Liu1,2, Lucero, Kimberly1,2, Vasilyev, Nikita1,2, Nudler, Evgeny1,2, Reinberg, Danny1,2 danny.reinberg@nyumc.org
Publikováno v:
Science Advances. 4/27/2022, Vol. 8 Issue 17, p1-11. 16p.
Autor:
Yilin Tai, Nicholas B. Gallo, Jia Ray Yu, Shinichi Nakamuta, Yu-Ting Yang, Chia-Lin Wang, Linda Van Aelst
Publikováno v:
The Journal of Cell Biology
Neuroblasts born postnatally in the ventricular–subventricular zone migrate long distances via the rostral migratory stream (RMS) to the olfactory bulb. Nakamuta et al. show that DOCK7 drives tangential migration of neuroblasts in the RMS by contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1130a958b2352f2710b0e2b8722ea527
https://doi.org/10.1083/jcb.201704157
https://doi.org/10.1083/jcb.201704157
Autor:
Yuki Aoi, Nicolas Descostes, Chul Hwan Lee, Danny Reinberg, Ali Shilatifard, Havva Ortabozkoyun Kara, Gary LeRoy, Jia Ray Yu, Ozgur Oksuz, Rais Ahmad Ganai, James M. Stafford
Publikováno v:
Science Advances
Chromatin-bound LEDGF and HDGF2 proteins allow RNAPII to overcome the nucleosome-induced block to transcription.
FACT (facilitates chromatin transcription) is a protein complex that allows RNA polymerase II (RNAPII) to overcome the nucleosome-in
FACT (facilitates chromatin transcription) is a protein complex that allows RNA polymerase II (RNAPII) to overcome the nucleosome-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ccff87d4099c16b382f5b88d50a675
http://europepmc.org/articles/PMC6774727
http://europepmc.org/articles/PMC6774727
As the process that silences gene expression ensues during development, the stage is set for the activity of Polycomb-repressive complex 2 (PRC2) to maintain these repressed gene profiles. PRC2 catalyzes a specific histone posttranslational modificat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f519a68e2cef263e89c1609b94c4b8
https://europepmc.org/articles/PMC6672058/
https://europepmc.org/articles/PMC6672058/
Autor:
Jia-Ray Yu1,2, LeRoy, Gary1,2, Bready, Devin3, Frenster, Joshua D.3, Saldaña-Meyer, Ricardo1,2, Ying Jin4, Descostes, Nicolas1,2,5, Stafford, James M.1,2,6, Placantonakis, Dimitris G.3,7,8,9,10, Reinberg, Danny1,2 danny.reinberg@nyulangone.org
Publikováno v:
Science Advances. 7/14/2021, Vol. 7 Issue 29, p1-9. 9p.
Autor:
James M. Stafford, Nicolas Descostes, Chul Hwan Lee, Rais Ahmad Ganai, Yuki Aoi, Havva Ortabozkoyun Kara, Ozgur Oksuz, Jia Ray Yu, Gary LeRoy, Danny Reinberg, Ali Shilatifard
FACT (facilitates chromatin transcription) is a protein complex that allows RNAPII to overcome the nucleosome-induced barrier to transcription. While abundant in undifferentiated cells and many cancers, FACT is not abundant or is absent in most tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc234185e4352f4c60bca1cb8cf03ddc
Autor:
Chul Hwan Lee, Aram S. Modrek, Philipp Voigt, Matija Snuderl, Beatrix Ueberheide, Jia Ray Yu, Nicolas Descostes, Matthias A. Karajannis, Ozgur Oksuz, Gary LeRoy, Fernando Suarez, N. Sumru Bayin, Danny Reinberg, James M. Stafford, Ricardo Saldaña-Meyer, Jessica R. Chapman, Dimitris G. Placantonakis
Publikováno v:
Science Advances
Stafford, J M, Lee, C H, Voigt, P, Descostes, N, Saldana-Meyer, R, Yu, J R, Leroy, G, Oksuz, O, Chapman, J R, Suarez, F, Modrek, A S, Bayin, N S, Placantonakis, D G, Karajannis, M A, Snuderl, M, Ueberheide, B & Reinberg, D 2018, ' Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma ', Science Advances, vol. 4, no. 10, eaau5935 . https://doi.org/10.1126/sciadv.aau5935
Stafford, J M, Lee, C H, Voigt, P, Descostes, N, Saldana-Meyer, R, Yu, J R, Leroy, G, Oksuz, O, Chapman, J R, Suarez, F, Modrek, A S, Bayin, N S, Placantonakis, D G, Karajannis, M A, Snuderl, M, Ueberheide, B & Reinberg, D 2018, ' Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma ', Science Advances, vol. 4, no. 10, eaau5935 . https://doi.org/10.1126/sciadv.aau5935
H3K27M transiently recruits PRC2 to chromatin but persistently affects its activity, leading to an aberrant epigenome in DIPG.
A methionine substitution at lysine-27 on histone H3 variants (H3K27M) characterizes ~80% of diffuse intrinsic pontine
A methionine substitution at lysine-27 on histone H3 variants (H3K27M) characterizes ~80% of diffuse intrinsic pontine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4e962e83b2ad484065bb2ed305452f
http://europepmc.org/articles/PMC6209383
http://europepmc.org/articles/PMC6209383