Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jia-Li Pu"'
Autor:
Si-Si Jiang, Yi-Ling Wang, Qiu-Han Xu, Lu-Yan Gu, Rui-Qing Kang, Wen-Yi Yang, Bao-Rong Zhang, Jun Tian, Jia-Li Pu
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Peripheral immune cells play a vital role in the development of Parkinson’s disease (PD). However, their cytokine and chemokine secretion functions remain unclear. Therefore, we aimed to explore the cytokine and chemokine secretion functio
Externí odkaz:
https://doaj.org/article/f138d6060e7c4b7294c3d66c184df774
Autor:
Ting Shen, Jia-Li Pu, Ya-Si Jiang, Yu-Mei Yue, Ting-Ting He, Bo-Yi Qu, Shuai Zhao, Ya-Ping Yan, Hsin-Yi Lai, Bao-Rong Zhang
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1154-1160 (2023)
Multiple single nucleotide polymorphisms may contribute to cognitive decline in Parkinson’s disease. However, the mechanism by which these single nucleotide polymorphisms modify brain imaging phenotype remains unclear. The aim of this study was to
Externí odkaz:
https://doaj.org/article/00cddb63b0cd4e5cbd8388ce1b393c70
Autor:
Jun Tian, Shao-Bing Dai, Si-Si Jiang, Wen-Yi Yang, Yi-Qun Yan, Zhi-Hao Lin, Jia-Xian Dong, Yi Liu, Ran Zheng, Ying Chen, Bao-Rong Zhang, Jia-Li Pu
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract Recent evidence suggests that innate and adaptive immunity play a crucial role in Parkinson’s disease (PD). However, studies regarding specific immune cell classification in the peripheral blood in PD remain lacking. Therefore, we aimed to
Externí odkaz:
https://doaj.org/article/2827508c733f441aa85b2c6745fcdaa6
Autor:
Xiao-Jun Guan, Tao Guo, Cheng Zhou, Ting Gao, Jing-Jing Wu, Victor Han, Steven Cao, Hong-Jiang Wei, Yu-Yao Zhang, Min Xuan, Quan-Quan Gu, Pei-Yu Huang, Chun-Lei Liu, Jia-Li Pu, Bao-Rong Zhang, Feng Cui, Xiao-Jun Xu, Min-Ming Zhang
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2743-2749 (2022)
Brain radiomics can reflect the characteristics of brain pathophysiology. However, the value of T1-weighted images, quantitative susceptibility mapping, and R2* mapping in the diagnosis of Parkinson’s disease (PD) was underestimated in previous stu
Externí odkaz:
https://doaj.org/article/df44762f656b4523ac337b409ea15681
Autor:
Chong-Yao Jin, Ran Zheng, Zhi-Hao Lin, Nai-Jia Xue, Ying Chen, Ting Gao, Yi-Qun Yan, Yi Fang, Ya-Ping Yan, Xin-Zhen Yin, Jun Tian, Jia-Li Pu, Bao-Rong Zhang
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background To date, the genetic contribution to Parkinson’s disease (PD) remains unclear. Mutations in the collagen type VI alpha 3 (COL6A3) gene were recently identified as a cause of isolated dystonia. Since PD and dystonia are closely r
Externí odkaz:
https://doaj.org/article/91c89c30e7af4b629c7fccd8877e61c6
Autor:
Wen-Yi Yang, Si-Si Jiang, Jia-Li Pu, Chong-Yao Jin, Ting Gao, Ran Zheng, Jun Tian, Bao-Rong Zhang
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
BackgroundParkinson's disease (PD) and dystonia are closely related in terms of pathophysiology and clinical manifestations, but their common genetic characteristics remain unclear. Some genome-wide association studies (GWASs) and replication studies
Externí odkaz:
https://doaj.org/article/62babbbb34554f4ebedeae613bb2de3f
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 3, Pp 501-505 (2019)
Differentiation of human fibroblasts into functional neurons depends on the introduction of viral-mediated transcription factors, which present risks of viral gene integration and tumorigenicity. In recent years, although some studies have been succe
Externí odkaz:
https://doaj.org/article/b6dd437945234c55839873bd05c1023c
Autor:
Jia-Li Pu, Ting Gao, Xiao-Li Si, Ran Zheng, Chong-Yao Jin, Yang Ruan, Yi Fang, Ying Chen, Zhe Song, Xin-Zhen Yin, Ya-Ping Yan, Jun Tian, Bao-Rong Zhang
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
IntroductionMutations in the teneurin transmembrane protein 4 (TENM4) gene, known to be involved in neuropsychiatric disorders, have been identified in three pedigree of essential tremor (ET) from Spain. ET has overlapping clinical manifestations and
Externí odkaz:
https://doaj.org/article/928b9c32e45845e989c833df6dd28318
Autor:
Xiao-li Si, Lu-yan Gu, Zhe Song, Cheng Zhou, Yi Fang, Chong-yao Jin, Jing-jing Wu, Ting Gao, Tao Guo, Xiao-jun Guan, Xiao-jun Xu, Xin-zhen Yin, Ya-ping Yan, Min-min Zhang, Jia-li Pu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
BackgroundExcessive aggregation of α-synuclein is the key pathophysiological feature of Parkinson’s disease (PD). Rapid eye movement sleep behavior disorder (RBD) is also associated with synucleinopathies and considered as a powerful predictor of
Externí odkaz:
https://doaj.org/article/58055be66ecf4b9da875495a1c22b82e
Autor:
Ran Zheng, Chong‐Yao Jin, Ying Chen, Yang Ruan, Ting Gao, Zhi‐Hao Lin, Jia‐Xian Dong, Ya‐Ping Yan, Jun Tian, Jia‐Li Pu, Bao‐Rong Zhang
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 10, Pp n/a-n/a (2020)
Abstract Background To date, several studies have suggested that genes involved in monogenic forms of Parkinson's disease (PD) contribute to unrelated sporadic cases, but there is limited evidence in the Chinese population. Methods We performed a sys
Externí odkaz:
https://doaj.org/article/b76fe851104f4230a488344c330ceaaa