Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jia-Jye Lee"'
Autor:
Dina Schneider, Bal Krishna Chand Thakuri, Saule Nurmukhambetova, Brittany Steimle, Peirong Hu, Pradyot Dash, Jia-Jye Lee, Tri Minh Tran, Ngoc Q Tran
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Chimeric antigen receptor (CAR) T-cell therapy target receptor tyrosine kinase-like orphan receptor 1 (ROR1) is broadly expressed in hematologic and solid tumors, however clinically-characterized ROR1-CAR T cells with single chain variable
Externí odkaz:
https://doaj.org/article/2594229ecd7a4d1abcd6fb73370fb956
Autor:
Dina Schneider, Bal Krishna Chand Thakuri, Saule Nurmukhambetova, Brittany Steimle, Ngoc Tran, Peirong Hu, Jia-Jye Lee, Kathleen Baysac, Tri M Tran
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4d64e328a01b432cb5270047a2ac8f20
Autor:
Rhodora C. Calizo, Smiti Bhattacharya, J. G. Coen van Hasselt, Chengguo Wei, Jenny S. Wong, Robert J. Wiener, Xuhua Ge, Nicholas J. Wong, Jia-Jye Lee, Christina M. Cuttitta, Gomathi Jayaraman, Vivienne H. Au, William Janssen, Tong Liu, Hong Li, Fadi Salem, Edgar A. Jaimes, Barbara Murphy, Kirk N. Campbell, Evren U. Azeloglu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Kinase inhibitors used in chemotherapy are known for their adverse effects on kidney physiology. Here, Calizo et al. show that dasatinib is associated with a higher risk of glomerular toxicity compared to other kinase inhibitors, due to deleterious e
Externí odkaz:
https://doaj.org/article/8269d038cbb047b6863d44efd06fc28f
Autor:
S. Michaela Rikard, Thomas L. Athey, Anders R. Nelson, Steven L. M. Christiansen, Jia-Jye Lee, Jeffrey W. Holmes, Shayn M. Peirce, Jeffrey J. Saucerman
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Wound healing and fibrosis following myocardial infarction (MI) is a dynamic process involving many cell types, extracellular matrix (ECM), and inflammatory cues. As both incidence and survival rates for MI increase, management of post-MI recovery an
Externí odkaz:
https://doaj.org/article/0a2f19745219486398d59b1542d70ba7
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 2, Pp 701-715 (2017)
Background/Aims: Our previous studies demonstrated that intrinsic aortic smooth muscle cell (VSMC) stiffening plays a pivotal role in aortic stiffening in aging and hypertension. However, the underlying molecular mechanisms remain largely unknown. We
Externí odkaz:
https://doaj.org/article/e448bf454feb445e8908cd5dd19299a1
Autor:
William J. Janssen, Hong Li, Tong Liu, J. G. Coen van Hasselt, Xuhua Ge, Gomathi Jayaraman, Jia-Jye Lee, Christina M. Cuttitta, Evren U. Azeloglu, Nicholas J. Wong, Robert J. Wiener, Fadi Salem, Edgar A. Jaimes, Rhodora Cristina Calizo, Smiti Bhattacharya, Chengguo Wei, Vivienne H. Au, Kirk N. Campbell, Jenny Wong, Barbara Murphy
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications, 10, 2061
Nature Communications
Nature Communications, 10, 2061
Nephrotoxicity is a critical adverse event that leads to discontinuation of kinase inhibitor (KI) treatment. Here we show, through meta-analyses of FDA Adverse Event Reporting System, that dasatinib is associated with high risk for glomerular toxicit
Publikováno v:
Biophysical Journal. 114:2717-2731
Atomic force microscopy (AFM) is used to study mechanical properties of biological materials at submicron length scales. However, such samples are often structurally heterogeneous even at the local level, with different regions having distinct mechan
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Cellular Physiology and Biochemistry, Vol 44, Iss 2, Pp 701-715 (2017)
Cellular Physiology and Biochemistry, Vol 44, Iss 2, Pp 701-715 (2017)
Background/Aims: Our previous studies demonstrated that intrinsic aortic smooth muscle cell (VSMC) stiffening plays a pivotal role in aortic stiffening in aging and hypertension. However, the underlying molecular mechanisms remain largely unknown. We
Autor:
Jia-Jye Lee, Kevin D. Costa, Charles Wang, Robert J. Wiener, Hongyu Qiu, Shaunrick Stoll, Ben Ma, Ning Zhou
Publikováno v:
Cardiovascular Research. 113:171-182
Increased aortic stiffness is a fundamental manifestation of hypertension. However, the molecular mechanisms involved remain largely unknown. We tested the hypothesis that abnormal intrinsic vascular smooth muscle cell (VSMC) mechanical properties in
Publikováno v:
Annals of Biomedical Engineering. 44:2994-3006
Marfan syndrome (MFS) is an autosomal dominant disease of the connective tissue due to mutations in the fibrillin-1 gene (FBN1). This study aimed at characterizing microelastic properties of the ascending aorta wall and lung parenchyma tissues from w