Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jia-Hui Tian"'
Autor:
Yong-Xiang He, Qi-Ying Shen, Jia-Hui Tian, Qian Wu, Qin Xue, Gui-Ping Zhang, Wei Wei, Ying-Hua Liu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Type 2 diabetes mellitus (T2DM) increases the risk of Alzheimer’s disease (AD)-like dementia and pathology. Endoplasmic reticulum stress (ERS) plays a key role in the development of cognitive impairment in T2DM. Zonisamide (ZNS) was found to suppre
Externí odkaz:
https://doaj.org/article/283913fada654e608cebc3f53a125601
Autor:
Xiao-bing Li, Mubarak Rekep, Jia-hui Tian, Qian Wu, Mei Chen, Shuo Yang, Lu-xuan Zhang, Gui-ping Zhang, Yuan Qin, Xi-yong Yu, Qin Xue, Ying-hua Liu
Publikováno v:
Pharmacology. 108(1)
Introduction: Luteolin is a flavonoid polyphenolic compound exerting broad pharmacological and medicinal properties. Diabetes-related obesity increases the total blood volume and cardiac output and may increase the myocardial hypertrophy progression.
Autor:
Jiandong Luo, Xi-Yong Yu, Yong-Xiang He, Yu-Qing Huang, Yong-Yin Huang, Qian Wu, Yinghua Liu, Jia-Hui Tian, Gui-Ping Zhang, Qin Xue
Publikováno v:
Acta Pharmacol Sin
Antiepileptic drug zonisamide has been shown to be curative for Parkinson’s disease (PD) through increasing HMG-CoA reductase degradation protein 1 (Hrd1) level and mitigating endoplasmic reticulum (ER) stress. Hrd1 is an ER-transmembrane E3 ubiqui
Autor:
Qi-ying Shen, Jiandong Luo, Gui-Ping Zhang, Qian Wu, Yinghua Liu, Yong-Xiang He, Jia-Hui Tian, Mubarak Rekep, Qin Xue
Publikováno v:
Acta Pharmacol Sin
Endoplasmic reticulum stress (ER stress) plays a key role in the development of cardiac hypertrophy and diabetic cardiomyopathy (DCM). Zonisamide (ZNS) was originally developed as an antiepileptic drug. Studies have shown that ZNS suppresses ER stres
Autor:
Qian Wu, Yinghua Liu, Jia-Hui Tian, Gui-Ping Zhang, Qin Xue, Qi-ying Shen, Wei Wei, Yong-Xiang He
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience
Type 2 diabetes mellitus (T2DM) increases the risk of Alzheimer’s disease (AD)-like dementia and pathology. Endoplasmic reticulum stress (ERS) plays a key role in the development of cognitive impairment in T2DM. Zonisamide (ZNS) was found to suppre
Autor:
Yinghua Liu, Qian Wu, Quan Yi, Qin Xue, Jia-Hui Tian, Sujuan Li, Jiandong Luo, Kui-Xiang Chen, Mubarak Rekep, Qing Xiao, Gen-Shui Zhang, Gui-Ping Zhang, Wei Wei
Publikováno v:
Cardiovascular drugs and therapy. 32(1)
Quercetin, a flavonoid, has been reported to ameliorate cardiovascular diseases, such as cardiac hypertrophy. However, the mechanism is not completely understood. In this study, a mechanism related to proteasome-glycogen synthesis kinase 3 (GSK-3) wa
Publikováno v:
DEStech Transactions on Social Science, Education and Human Science.
Determined by the nature of the mechanical product, there is plenty of room for the application of value engineering in the design process. However, the application of value engineering is too theoretical, and practical guiding significance has great