Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jia-Huang Chen"'
Autor:
Jia-Huang Chen, Chia-Hsien Wu, Jia-Rong Jheng, Chia-Ter Chao, Jenq-Wen Huang, Kuan-Yu Hung, Shing-Hwa Liu, Chih-Kang Chiang
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-22 (2022)
Abstract Background The activation of the unfolded protein response (UPR) is closely linked to the pathogenesis of renal injuries. However, the role of XBP1, a crucial regulator of adaptive UPR, remains unclear during the transition from acute kidney
Externí odkaz:
https://doaj.org/article/f218a9b974ca457ba62c988086e6a975
Autor:
Jia-Huang Chen, Chih-Kang Chiang
Publikováno v:
Toxins, Vol 14, Iss 1, p 8 (2021)
Uremic toxins are defined as harmful metabolites that accumulate in the human body of patients whose renal function declines, especially chronic kidney disease (CKD) patients. Growing evidence demonstrates the deteriorating effect of uremic toxins on
Externí odkaz:
https://doaj.org/article/d6b76eb4dd3e43688df57bf071484336
Autor:
Chong-Sun Khoi, Yu-Wen Lin, Jia-Huang Chen, Biing-Hui Liu, Tzu-Yu Lin, Kuan-Yu Hung, Chih-Kang Chiang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 10951 (2021)
Ochratoxin A (OTA), one of the major food-borne mycotoxins, impacts the health of humans and livestock by contaminating food and feed. However, the underlying mechanism of OTA nephrotoxicity remains unknown. This study demonstrated that OTA induced a
Externí odkaz:
https://doaj.org/article/da5266604e974294bd88d9b39fc7d9e7
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11237 (2021)
Ochratoxin A (OTA) is a mycotoxin widely found in various foods and feeds that have a deleterious effect on humans and animals. It has been shown that OTA causes multiorgan toxicity, and the kidney is the main target of OTA among them. This present a
Externí odkaz:
https://doaj.org/article/ec9a05ffe7cc411183c0461fd10455c0
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8674 (2021)
Pathological insults usually disturb the folding capacity of cellular proteins and lead to the accumulation of misfolded proteins in the endoplasmic reticulum (ER), which leads to so-called “ER stress”. Increasing evidence indicates that ER stres
Externí odkaz:
https://doaj.org/article/d9464318124c48569337b47fc9af684b
Autor:
CHIH-KANG CHIANG, Jia-Huang Chen
Publikováno v:
Toxins, Vol 14, Iss 8, p 8 (2022)
Toxins
Toxins
Uremic toxins are defined as harmful metabolites that accumulate in the human body of patients whose renal function declines, especially chronic kidney disease (CKD) patients. Growing evidence demonstrates the deteriorating effect of uremic toxins on
Autor:
Jia-Huang Chen, Chong-Sun Khoi, Chih-Kang Chiang, Biing-Hui Liu, Tzu-Yu Lin, Kuan-Yu Hung, Yu-Wen Lin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10951, p 10951 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences
Volume 22
Issue 20
Ochratoxin A (OTA), one of the major food-borne mycotoxins, impacts the health of humans and livestock by contaminating food and feed. However, the underlying mechanism of OTA nephrotoxicity remains unknown. This study demonstrated that OTA induced a
Autor:
Chia-Ter Chao, Shing-Hwa Liu, Chih-Kang Chiang, Der-Cherng Tarng, Jenq-Wen Huang, Kuan-Yu Hung, Jia Huang Chen
Publikováno v:
Clinical science (London, England : 1979). 135(23)
Acute kidney injury (AKI)-related fibrosis is emerging as a major driver of chronic kidney disease (CKD) development. Aberrant kidney recovery after AKI is multifactorial and still poorly understood. The accumulation of indoxyl sulfate (IS), a protei
Autor:
Jia-Huang Chen, Chia-Ter Chao, Jenq-Wen Huang, Kuan-Yu Hung, Shing-Hwa Liu, Der-Cherng Tarng, Chih-Kang Chiang
Publikováno v:
Clinical Science; Dec2021, Vol. 135 Issue 23, p2643-2658, 16p
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 11237, p 11237 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 11237, p 11237 (2021)
Ochratoxin A (OTA) is a mycotoxin widely found in various foods and feeds that have a deleterious effect on humans and animals. It has been shown that OTA causes multiorgan toxicity, and the kidney is the main target of OTA among them. This present a