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Autor:
Jia-Hua Tong, S. Dong, Zhen-Yi Wang, Jin-Ren Cai, Christian-Jacques Larsen, Yu Wu, Shu-Rong Chen, Zhu Chen, Guan-Lin Sun, Roland Berger, Sai-Juan Chen, Jie-Ping Geng
Publikováno v:
Genes, Chromosomes and Cancer. 6:133-139
DNA studies of the translocation t(15;17) in acute promyelocytic leukemia (APL) have shown that the retinoic acid receptor alpha (RARA) gene on chromosome 17 is juxtaposed to the promyelocytic leukemia (PML) gene on chromosome 15. The PML breakpoints