Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Jia Xin Chen"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 5, Pp 2069-2077 (2015)
Background: Genistein, a major isoflavonoid isolated from dietary soybean, has been shown to suppress the growth of several cancers through modulation of various pathways. However, the molecular mechanisms by which genistein elicit its effects on col
Externí odkaz:
https://doaj.org/article/366b8df05fb3454d928f359d37d0d37e
Autor:
Si-chen Di, Wen-jin Chen, Wei Yang, Xiang-min Zhang, Ke-qin Dong, Yi-jun Tian, Ye Sun, Cheng Qian, Jia-xin Chen, Zi-chang Liu, Zi-xuan Gong, Jian Chu, Wang Zhou, Xiu-wu Pan, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-13 (2024)
Abstract Renal cell carcinoma (RCC) is considered a “metabolic disease” characterized by elevated glycolysis in patients with advanced RCC. Tyrosine kinase inhibitor (TKI) therapy is currently an important treatment option for advanced RCC, but d
Externí odkaz:
https://doaj.org/article/78619da7dff9410ab9cd5808a6be5d1a
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Extracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to evaluate changes in ECM remodeling in the lumbar paravertebral muscles of sarcopenic rats using
Externí odkaz:
https://doaj.org/article/ea718837d89a4f94a98cd027399175b2
Autor:
Yang Xiang, Bo-han Pan, Jin Zhang, Ji-qiu Chen, He Fang, Qun Wang, Lin-hui Li, Tian-sheng Chen, Jia-xin Chen, Chan Li, Xing-feng Zheng, Shi-hui Zhu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSevere burns can lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) due to inflammation-immunity dysregulation. This study aimed to identify key immune-related molecules and potential drugs
Externí odkaz:
https://doaj.org/article/76413341d0ce4285aea4ae6c247b483a
Autor:
Da Xu, LI Zuo, Wang Zhou, Yu-Qi Wang, Wen-Jin Chen, Ke-Qin Dong, Jia-Xin Chen, Wei-Jie Chen, Wen-Yan Li, Zi-Chang Liu, Zheng-Yu Jiang, Yi-Fan Tang, Yu-Xuan Qin, Lin-Hui Wang, Xiu-Wu Pan, Xin-Gang Cui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background Tertiary lymphoid structures (TLSs) serve as organized lymphoid aggregates that influence immune responses within the tumor microenvironment. This study aims to investigate the characteristics and clinical significance of TLSs and tumor-in
Externí odkaz:
https://doaj.org/article/a822db8f99ba4850b4ab5171fa2903aa
Publikováno v:
Defence Technology, Vol 27, Iss , Pp 38-45 (2023)
As the representative of flexibility in optical imaging media, in recent years, fiber bundles have emerged as a promising architecture in the development of compact visual systems. Dedicated to tackling the problems of universal honeycomb artifacts a
Externí odkaz:
https://doaj.org/article/86b510e68a4d478ba6e674fb4074fea6
Autor:
Xiu-wu Pan, Wen-jin Chen, Da Xu, Wen-bin Guan, Lin Li, Jia-xin Chen, Wei-jie Chen, Ke-qin Dong, Jian-qing Ye, Si-shun Gan, Wang Zhou, Xin-gang Cui
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108370- (2023)
Summary: Previous bulk RNA sequencing or whole genome sequencing on clear cell renal cell carcinoma (ccRCC) subtyping mainly focused on ccRCC cell origin or the complex tumor microenvironment (TME). Based on the single-cell RNA sequencing (scRNA-seq)
Externí odkaz:
https://doaj.org/article/778c05f700f34d5cbdde9e7a39873011
Autor:
Xin-Chen Huang, Yi-Long Huang, Yi-Tong Guo, Si-Yu Li, Chao Gao, Jia-Xin Chen, Ji-Yao Ma, Bo He
Publikováno v:
Experimental Gerontology, Vol 183, Iss , Pp 112322- (2023)
Background: Severe sarcopenia may result in severe disability. Early diagnosis is currently the key to enhancing the treatment of sarcopenia, and there is an urgent need for a highly sensitive and dependable tool to evaluate the course of early sarco
Externí odkaz:
https://doaj.org/article/e4f48bc1105d495fb8bcf946922fc6cc
Autor:
Wen-jin Chen, Ke-qin Dong, Xiu-wu Pan, Si-shun Gan, Da Xu, Jia-xin Chen, Wei-jie Chen, Wen-yan Li, Yu-qi Wang, Wang Zhou, Brian Rini, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Tumor growth, metastasis and therapeutic response are believed to be regulated by the tumor and its microenvironment (TME) in advanced renal cell carcinoma (RCC). However, the mechanisms underlying genomic, transcriptomic and epigenetic alte
Externí odkaz:
https://doaj.org/article/d2a358035a5a4a40aeec5e85972cefbd
Autor:
Wen-jin Chen, Hao Cao, Jian-wei Cao, Li Zuo, Fa-jun Qu, Da Xu, Hao Zhang, Hai-yi Gong, Jia-xin Chen, Jian-qing Ye, Si-shun Gan, Wang Zhou, Da-wei Zhu, Xiu-Wu Pan, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Non-clear renal cell carcinomas (nccRCCs) are less frequent in kidney cancer with histopathological heterogeneity. A better understanding of the tumor biology of nccRCC can provide more effective treatment paradigms for different subtypes. T
Externí odkaz:
https://doaj.org/article/cb6fa662dd4e457ab9e5f8192511f2ec