Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jia Wu Zhu"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121666 (2015)
TRIMCyp is a fusion protein consisting of the TRIM5 gene product and retrotransposed Cyclophilin A (CypA). Two primate TRIMCyp fusion proteins with varying anti-HIV-1 activities independently evolved in owl monkeys and Old World monkeys. In addition,
Externí odkaz:
https://doaj.org/article/f1469be542084d9aa8636461acb1f064
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Tripartite motif-containing protein 5α (TRIM5α) is generally known to block the postentry events of HIV-1. Here, we report an uncharacterized role for TRIM5α in the maintenance of viral latency. Knockdown of TRIM5α potentiates the transc
Externí odkaz:
https://doaj.org/article/46e1520c060a49c399947f0fb7761cb5
Publikováno v:
Frontiers in Immunology; 8/12/2022, Vol. 13, p1-13, 13p
Publikováno v:
Molecular Immunology. 101:627-634
TRIMCyp generated by retrotransposition of a cyclophilin A inserting into TRIM5 locus, has been identified in owl monkey and most of Old World monkeys (OWM). Owl monkey TRIMCyp (omTRIMCyp) inhibits HIV-1 infection by direct interaction with viral cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004ac60419f56227d3ae42a7122c3aef
https://doi.org/10.1016/j.molimm.2018.08.001
https://doi.org/10.1016/j.molimm.2018.08.001
Autor:
Ming Xu Zhang, Wei Pang, Xiao Ming Liu, Yong-Tang Zheng, Ai Hua Lei, Hong Yi Zheng, Lin Tao Zhang, Jia Hao Song, Ren Rong Tian, Guangxia Gao, Xiao-Liang Zhang, Gao Hong Zhang, Lishan Su, Liguo Zhang, Jia Wu Zhu, Jin Jiang
Publikováno v:
Science Bulletin. 62:1315-1324
Viral reservoirs of HIV-1 are a major obstacle for curing AIDS. The novel animal models that can be directly infected with HIV-1 will contribute to develop effective strategies for eradicating infections. Here, we inoculated 4 northern pig-tailed mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::932af3b2add29e16d812766b5bae2923
https://doi.org/10.1016/j.scib.2017.09.020
https://doi.org/10.1016/j.scib.2017.09.020
Publikováno v:
Archives of Virology. 161:3019-3027
HIV-1-infected macrophages are long-lived and act as human immunodeficiency virus 1 (HIV-1) virus reservoirs. Lipopolysaccharide (LPS) has been demonstrated to suppress HIV-1 replication in macrophages, but the mechanism is not clear. Previous resear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c189de2234fa2d3bff50b40ef1f0c47
https://doi.org/10.1007/s00705-016-3000-y
https://doi.org/10.1007/s00705-016-3000-y
Publikováno v:
Science China. Life sciences. 61(8)
TRIM5α restricts retroviruses in a species-specific manner. Cyclophilin A was independently retrotransposed into the TRIM5 loci in different species, leading to the generation of antiviral TRIM5-cyclophilin A (TRIMCyp) proteins. Previously, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845c156e01cfe0d4f03cc82c356b7b3b
https://pubmed.ncbi.nlm.nih.gov/29705873
https://pubmed.ncbi.nlm.nih.gov/29705873
Publikováno v:
Journal of Medical Virology. 88:987-995
Host restriction factors and type I interferon are important in limiting HIV and HCV infections, yet the role of HIV, HCV mono- and co-infection in regulating these antiviral genes expression is not clear. In this study, we measured the levels of TRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b102c2215e101316ccd7e7b1e781c87a
https://doi.org/10.1002/jmv.24419
https://doi.org/10.1002/jmv.24419
Publikováno v:
Archives of Virology. 148:1301-1316
Menangle virus is a novel paramyxovirus isolated in Australia in 1997, but its classification position has not yet been finally settled. Here by using a computational program, LearnCoil-VMF, we determined the heptad repeat (HR) regions (HR1 and HR2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c28d5f110f57a4e0a63dbe9e1ec603
https://doi.org/10.1007/s00705-003-0105-x
https://doi.org/10.1007/s00705-003-0105-x
Autor:
Dan Mu, Hong-Yi Zheng, Jia-Wu Zhu, Hui Yang, Yong-Tang Zheng, Feng-Liang Liu, Jian-Bao Han, Peng Shi, Ren-Rong Tian
Publikováno v:
Molecular biology and evolution. 31(11)
The origin of novel genes and their evolutionary fates are long-standing questions in evolutionary biology. These questions become more complicated for genes conserved across various lineages, such as TRIM5, an antiretroviral restriction factor and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09e0425f72c42b7ae65973fb6c5ecc0
https://pubmed.ncbi.nlm.nih.gov/25135944
https://pubmed.ncbi.nlm.nih.gov/25135944