Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jia Rong Liu"'
Autor:
Kang-Li Wang, Tsung-Yu Yeh, Pei-Chen Hsu, Tzu-Hsuan Wong, Jia-Rong Liu, Ji-Wang Chern, Miao-Hsia Lin, Chao-Wu Yu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractA series of novel benzimidazole derivatives were designed and synthesised based on the structures of reported oral available ALK inhibitor and HDAC inhibitor, pracinostat. In enzymatic assays, compound 3b, containing a 2-acyliminobenzimidazol
Externí odkaz:
https://doaj.org/article/17426bfae6b842ee8c54f5e27cc5db57
Autor:
Shun Hu Zhang, Jia Rong Liu
Publikováno v:
International Journal of Pressure Vessels and Piping. 200:104832
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a45a02d289ea1d6f434f27aa3d82999a
https://doi.org/10.1016/j.ijpvp.2022.104832
https://doi.org/10.1016/j.ijpvp.2022.104832
Publikováno v:
Environmental pollution (Barking, Essex : 1987). 263
Rare earth elements (REEs) are widely used in optoelectronic industries, and they can be emitted into the environment and may induce biological effects. In this study, we investigated the provenance and bioaccessibility of REEs in atmospheric particl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6698dc71d4e8605df79e81576eab950
https://pubmed.ncbi.nlm.nih.gov/32244157
https://pubmed.ncbi.nlm.nih.gov/32244157
Publikováno v:
ACS Medicinal Chemistry Letters. 10:22-26
[Image: see text] We demonstrate that the acrylamide group can be used to improve the drug-like properties of potential drug candidates. In the EGFR inhibitor development, both the solubility and membrane permeability properties of compounds 6a and 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afc28051842cb1a87250d5ff42cedcb
https://doi.org/10.1021/acsmedchemlett.8b00270
https://doi.org/10.1021/acsmedchemlett.8b00270
Autor:
Sheang-Tze Fung, Yi-Hsun Ho, Pi-Hui Liang, Kuang-Jui Wang, Ji-Wang Chern, Jia-Rong Liu, Chao-Wu Yu, Pei-Yun Hung, Yi-Sheng Cheng
Publikováno v:
Organic & Biomolecular Chemistry. 16:7820-7832
HDAC6 receives great attention because of its therapeutic potential for the treatment of various diseases. Selective fluorescence imaging for HDAC6 is important for its pathological and biological studies. However, specific detection of HDAC6 by usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94709fc91b0939244044b6eb0103e2a0
https://doi.org/10.1039/c8ob00966j
https://doi.org/10.1039/c8ob00966j
Publikováno v:
International Journal of Pressure Vessels and Piping. 194:104561
In order to solve the problem of insufficient accuracy in predicting the burst pressure of a pipe elbow based on the existing yield criteria, a new yield criterion is established firstly and then used to analyze the plastic failure of a pipe elbow. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7fcd21ad9025dff2b38075463e18d12
https://doi.org/10.1016/j.ijpvp.2021.104561
https://doi.org/10.1016/j.ijpvp.2021.104561
Publikováno v:
2019 10th International Conference on Information Technology in Medicine and Education (ITME).
Objective: A prototype of the quality traceability system of Traditional Chinese Medicine (TCM) based on two-dimensional barcode using mobile intelligent technology was designed and developed. Methods: Through reviewing the current major tracing tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6f33152e8a548a798b7be93e9fda4e3
https://doi.org/10.1109/itme.2019.00044
https://doi.org/10.1109/itme.2019.00044
Publikováno v:
Biochemical pharmacology. 163
Glioblastoma is the most fatal type of primary brain cancer, and current treatments for glioblastoma are insufficient. HDAC6 is overexpressed in glioblastoma, and siRNA-mediated knockdown of HDAC6 inhibits glioma cell proliferation. Herein, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322a61cf8a1a6b8f5228d661e590f1e9
https://pubmed.ncbi.nlm.nih.gov/30885763
https://pubmed.ncbi.nlm.nih.gov/30885763
Autor:
Ji-Wang Chern, Chao-Wu Yu, Cheng Peng, Ze-Hua Cheng, Yu-Hsuan Li, Yi-Sheng Cheng, Chen Tsung Huang, Ling-Wei Hsin, Jui-Ling Hsu, Hsueh Fen Juan, Jia-Rong Liu
Publikováno v:
Bioorganic Chemistry. 110:104813
MutT Homolog 1 (MTH1) has been proven to hydrolyze oxidized nucleotide triphosphates during DNA repair. It can prevent the incorporation of wrong nucleotides during DNA replication and mitigate cell apoptosis. In a cancer cell, abundant reactive oxyg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7508533409aa29a57206b5185319d7df
https://doi.org/10.1016/j.bioorg.2021.104813
https://doi.org/10.1016/j.bioorg.2021.104813
Autor:
Hong-bo WU, Jia-rong LIU, Hui-juan WU, Xiu-li ZHAO, Li-juan CHEN, Xiao-qian MU, Xiu-feng HU, Hong-zhi ZOU, Yan-qiu ZHAO
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 40, Iss 6, Pp 467-471 (2015)
Objective To investigate the expression of DKK1 in the tissues of esophageal squamous cell carcinoma (ESCC) and its relation with the clinicopathological features and prognosis of ESCC. Methods The expression of DKK1 were assessed by immunohistochemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::16f9a2fe0d26e1dbd8024d5ff24f38c2
http://www.plamj.org/index.php/plamj/article/view/1155
http://www.plamj.org/index.php/plamj/article/view/1155