Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jia Qi Tng"'
Autor:
Yichao Cai, Ying Zhang, Yan Ping Loh, Jia Qi Tng, Mei Chee Lim, Zhendong Cao, Anandhkumar Raju, Erez Lieberman Aiden, Shang Li, Lakshmanan Manikandan, Vinay Tergaonkar, Greg Tucker-Kellogg, Melissa Jane Fullwood
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Mechanisms underlying gene repression and silencers remain poorly understood. Here the authors investigate the role of H3K27me3-rich regions in the genome, as defined from clusters of H3K27me3 peaks, in regulating gene expression via looping.
Externí odkaz:
https://doaj.org/article/d3b2681ce73046bd90d6e3a3c6cb6762
Autor:
Shweta Pradip Jadhav, Nishi Kumari, Larry Ng, Pei Fang Tan, Nicole Shu Ling Yeo-Teh, Yufen Goh, Wee Nih Fam, Jia Qi Tng, Johann Shane Tian, Bryan T. H. Koh, Chan Ming Chun, Wilson Wang, Wee Joo Chng, Melissa Jane Fullwood, Ernesto Guccione, Neerja Karnani, Daniel G. Tenen, Sudhakar Jha
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
Externí odkaz:
https://doaj.org/article/c6d689f208794cfdb06ff5e2260d5be8
Autor:
Ernesto Guccione, Wee Joo Chng, Bryan T. H. Koh, Pei Fang Tan, Nicole Shu Ling Yeo-Teh, Johann Shane Tian, Melissa J. Fullwood, Larry Ng, Shweta Pradip Jadhav, Wilson Wang, Daniel G. Tenen, Wee Nih Fam, Yufen Goh, Nishi Kumari, Jia Qi Tng, Neerja Karnani, Chan Ming Chun, Sudhakar Jha
Publikováno v:
Haematologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378cb9ed23a3b348db42af708ea1fb58
https://doi.org/10.3324/haematol.2019.225961
https://doi.org/10.3324/haematol.2019.225961
Autor:
Greg Tucker-Kellogg, Ying Zhang, Zhendong Cao, Mei Chee Lim, Yichao Cai, Melissa J. Fullwood, Shang Li, Erez Lieberman Aiden, Yan Ping Loh, Lakshmanan Manikandan, Anandhkumar Raju, Vinay Tergaonkar, Jia Qi Tng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Nature Communications
Nature Communications
The mechanisms underlying gene repression and silencers are poorly understood. Here we investigate the hypothesis that H3K27me3-rich regions of the genome, defined from clusters of H3K27me3 peaks, may be used to identify silencers that can regulate g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c832ce97f2015b1b7f55a8e5aac7d20
https://hdl.handle.net/10356/146349
https://hdl.handle.net/10356/146349
Autor:
Ming Chun Chan, Wee Joo Chng, Touati Benoukraf, Xin Liu, Deepak Babu, Fang Fang Song, Ruchi Choudhary, Melissa J. Fullwood, Priscella Shirley Chia, Lingshi Kong, Wilson Wang, Yufen Goh, Omer An, Winnie Fam, Henry Yang, Daniel G. Tenen, Jia Qi Tng, Cheng Yong Tham, Benny Wang
Acute Myeloid Leukemia (AML) is a highly lethal blood cancer arising due to aberrant differentiation of haematopoietic stem cells. Here we obtained 3D genome organization maps by Hi-C in the CD34+ haematopoietic stem cells from three healthy individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3bb675f417c9e09d0aa5b75138072ef
https://doi.org/10.1101/2020.04.18.047738
https://doi.org/10.1101/2020.04.18.047738
Autor:
Ming Chun Chan, Benny Wang, Fang Fang Song, Ruchi Choudhary, Lingshi Kong, Cheng Yong Tham, Xin Liu, Henry Yang, Daniel G. Tenen, Jia Qi Tng, Omer An, Wee Joo Chng, Winnie Fam, Wilson Wang, Yufen Goh, Priscella Shirley Chia, Deepak Babu, Touati Benoukraf, Melissa J. Fullwood
Publikováno v:
Cancer Research. 81:LB189-LB189
Many oncogenes, such as MEIS1 and HOXA9, are overexpressed in some but not all cancers. We identified two key epigenetic mechanisms underlying this heterogeneity in oncogene expression in Acute Myeloid Leukemia. Acute Myeloid Leukemia (AML) is a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aad8d726bb0a4f9b9fba0149d2a2370a
https://doi.org/10.1158/1538-7445.am2021-lb189
https://doi.org/10.1158/1538-7445.am2021-lb189