Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jia Q. Truong"'
Autor:
Ayeshah A. Rosdah, Belinda M. Abbott, Christopher G. Langendorf, Yali Deng, Jia Q. Truong, Helen M. M. Waddell, Naomi X. Y. Ling, William J. Smiles, Lea M. D. Delbridge, Guei-Sheung Liu, Jonathan S. Oakhill, Shiang Y. Lim, Jessica K. Holien
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial dynamics and is known to play an important role in numerous pathophysiological processes. Despite being the most widely used Drp1 inhibitor, the spec
Externí odkaz:
https://doaj.org/article/81d43f7ed5984ba3b02b0644c4d9b73f
Autor:
Vivian Cody, Jia Q. Truong, Bruce A. Holdsworth, Jessica K. Holien, Samantha J. Richardson, David K. Chalmers, David J. Craik
Publikováno v:
Molecules, Vol 27, Iss 21, p 7206 (2022)
Human transthyretin (hTTR) can form amyloid deposits that accumulate in nerves and organs, disrupting cellular function. Molecules such as tafamidis that bind to and stabilize the TTR tetramer can reduce such amyloid formation. Here, we studied the i
Externí odkaz:
https://doaj.org/article/456a38735a2245eab13bbe0e53f542cb
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
The impact of invasive fungal infections on human health is a serious, but largely overlooked, public health issue. Commonly affecting the immunocompromised community, fungal infections are predominantly caused by species of Candida, Cryptococcus, an
Externí odkaz:
https://doaj.org/article/abb5a36ea1bd49f1b6ca2143d77473ee
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 90:1509-1520
The metabolic enzyme, enolase, plays a crucial role in the cytoplasm where it maintains cellular energy production within the process of glycolysis. The main role of enolase in glycolysis is to convert 2-phosphoglycerate to phosphoenolpyruvate; howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa20b7a9abb36c056fd5a8b04e6465ae
https://doi.org/10.1002/prot.26331
https://doi.org/10.1002/prot.26331
Autor:
Ayeshah A. Rosdah, Belinda M. Abbott, Christopher G. Langendorf, Yali Deng, Jia Q. Truong, Helen M. M. Waddell, Naomi X. Y. Ling, William J. Smiles, Lea M. D. Delbridge, Guei-Sheung Liu, Jonathan S. Oakhill, Shiang Y. Lim, Jessica K. Holien
Mitochondrial dynamin-related protein 1 (Drp1) is a large GTPase regulator of mitochondrial dynamics and is known to play an important role in numerous pathophysiological processes. Despite being the most widely used Drp1 inhibitor, the specificity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a9619ddb93dfb9fcff13ce685136a5
Autor:
Craik, Vivian Cody, Jia Q. Truong, Bruce A. Holdsworth, Jessica K. Holien, Samantha J. Richardson, David K. Chalmers, David J.
Publikováno v:
Molecules; Volume 27; Issue 21; Pages: 7206
Human transthyretin (hTTR) can form amyloid deposits that accumulate in nerves and organs, disrupting cellular function. Molecules such as tafamidis that bind to and stabilize the TTR tetramer can reduce such amyloid formation. Here, we studied the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::b7ce076eee49a0c6e21a87945c8b2ac6
Publikováno v:
Acta Crystallogr F Struct Biol Commun
The phase problem is a persistent bottleneck that impedes the structure-determination pipeline and must be solved to obtain atomic resolution crystal structures of macromolecules. Although molecular replacement has become the predominant method of so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996d9732a1de9821439055dd5e6594e1
https://pubmed.ncbi.nlm.nih.gov/33949976
https://pubmed.ncbi.nlm.nih.gov/33949976