Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jia Li Chu"'
Publikováno v:
Arthritis & Rheumatism. 52:225-238
Objective To examine the ability of mature dendritic cells (DCs) or macrophages intentionally exposed to lipopolysaccharide or apoptotic or necrotic cells to break tolerance in normal mice. Methods We adoptively transferred into C57BL/6 mice a variet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1bbdb3a4021b76ae13f79bfae92047
https://doi.org/10.1002/art.20759
https://doi.org/10.1002/art.20759
Autor:
Andrew P. Parnassa, Jason A. Wexler, Jia Li Chu, Robert D. Blank, Keith B. Elkon, Robert J. Wurzburger, Sargam Jain, Rajarsi Gupta
Publikováno v:
Clinical Medicine & Research. 1:111-118
Objective Development of a systematic mutation detection assay strategy for denaturing high performance liquid chromatography (DHPLC). Design Adaptation of Guanine and Cytosine (GC)-clamping from denaturing gradient gel electrophoresis (DGGE) to DHPL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9ed6d76b3888c996af364651e975f7
https://doi.org/10.3121/cmr.1.2.111
https://doi.org/10.3121/cmr.1.2.111
Autor:
Larry Zemel, Akshay Vaishnaw, Jaime Estrada, Anneliese L. Sitarz, Elias Toubi, Saundra S. Buys, Jia Li Chu, Satomi Ohsako, Jörn Drappa, Keith B. Elkon
Publikováno v:
Arthritis & Rheumatism. 42:1833-1842
Objective To determine the clinical spectrum of disease in humans with mutations in the CD95 (Fas/APO-1) receptor and to obtain mechanistic insight into the different clinical phenotypes observed. Methods Clinical information for each of the index ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a59c9b0ddd537cfac0997961d415ef94
https://doi.org/10.1002/1529-0131(199909)42:9<1833::aid-anr7>3.0.co
https://doi.org/10.1002/1529-0131(199909)42:9<1833::aid-anr7>3.0.co
Publikováno v:
New England Journal of Medicine. 335:1643-1649
The Canale-Smith syndrome is a childhood disorder characterized by lymphadenopathy and autoimmunity. The similarity between this syndrome and that in mice with the lymphoproliferation (lpr) phenotype or the generalized-lymphoproliferative-disease (gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9f73575cacf405b5f1f95f5f2a7f43
https://doi.org/10.1056/nejm199611283352204
https://doi.org/10.1056/nejm199611283352204
Publikováno v:
The Journal of Experimental Medicine
Fas-deficient lpr and gld mice develop lymphadenopathy due to the accumulation of T cells with an unusual double negative (DN) (CD4-CD8-) phenotype. Previous studies have shown that these abnormal cells are capable of inducing redirected lysis of cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933899400204f3206a67a74f33ca9e4e
http://europepmc.org/articles/PMC2191821
http://europepmc.org/articles/PMC2191821
Publikováno v:
The Journal of Experimental Medicine
Fas is a cell surface protein of the tumor necrosis factor receptor, nerve growth factor receptor, CD40 family, and is involved in the control of lymphocyte apoptosis. A mutation in the Fas gene in MRL/lpr mice results in massive lymphoproliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9994ffeb2ce5eddfc51163218b3c10a
https://doi.org/10.1084/jem.178.2.723
https://doi.org/10.1084/jem.178.2.723
Publikováno v:
The Journal of Experimental Medicine
The ribosomal P proteins are necessary for GTPase activity during protein synthesis. In addition to antibodies to the P proteins, sera from lupus patients contain anti-rRNA activity. To determine whether lupus antiribosomal sera recognize the region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2d29ac5036a6b646b6cbaef40fb17b
https://pubmed.ncbi.nlm.nih.gov/1875164
https://pubmed.ncbi.nlm.nih.gov/1875164
Autor:
Peter H. Krammer, Jia Li Chu, Akshay Vaishnaw, Moses V. Chao, Keith B. Elkon, Jason R. Orlinick
Publikováno v:
Journal of Clinical Investigation. 103:1099-1099
Heterozygous mutations of the receptor CD95 (Fas/Apo-1) are associated with defective lymphocyte apoptosis and a clinical disease characterized by lymphadenopathy, splenomegaly, and systemic autoimmunity. From our cohort of 11 families, we studied ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24a5a5f351296342dd7a1202d95ea24
https://doi.org/10.1172/jci5121c1
https://doi.org/10.1172/jci5121c1
Mature dendritic cells readily break tolerance in normal mice but do not lead to disease expression.
Publikováno v:
Arthritis & Rheumatism; Jan2005, Vol. 52 Issue 1, p225-238, 14p
Publikováno v:
Electrophoresis. 8:445-451
Immunoblotting has proven to be one of the most useful methods for detection of antibodies and partial characterization of proteins that are antigenic in the autoimmune diseases. The basic physicochemical characteristics (size and charge) of most of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f03b53870a39a05f96fd7d8daa07e2
https://doi.org/10.1002/elps.1150080914
https://doi.org/10.1002/elps.1150080914