Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jia L. Zhu"'
Autor:
Kim W. McIntyre, Luisa Salter-Cid, Bethanne M. Warrack, Celia D’Arienzo, Lois D. Lehman-McKeeman, Rochelle Thomas, Praveen Balimane, Anthony M. Marino, Joel C. Barrish, Elizabeth M. Heimrich, Ding Ren Shen, Xiaoxia Yang, Xia D. Zhou, Jenny Xie, Hong Shi, T. G. Murali Dhar, James Hennan, Jia L. Zhu, Dauh-Rurng Wu, Marta Dabros, Paul Levesque, Percy H. Carter, Arvind Mathur, Mary Ellen Cvijic, Alaric J. Dyckman, Georgia Cornelius, Zheng Yang, Hai-Yun Xiao, Tracy L. Taylor
Publikováno v:
ACS Medicinal Chemistry Letters. 7:283-288
Clinical validation of S1P receptor modulation therapy was achieved with the approval of fingolimod (Gilenya, 1) as the first oral therapy for relapsing remitting multiple sclerosis. However, 1 causes a dose-dependent reduction in the heart rate (bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468b1729fdb8306c92c42940224441d3
https://doi.org/10.1021/acsmedchemlett.5b00448
https://doi.org/10.1021/acsmedchemlett.5b00448
Publikováno v:
Journal of Molecular and Cellular Cardiology. 30:415-423
The contribution of adrenergic stimulation to the proarrhythmic effects of pinacidil (30 microM), an opener of ATP-sensitive potassium channels (K+ATP), was tested in an isolated guinea-pig heart model of global ischemia (10 min) and reperfusion (10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835556e2200fc3816f38f63f599c61b7
https://doi.org/10.1006/jmcc.1997.0605
https://doi.org/10.1006/jmcc.1997.0605
Autor:
Paul G. Sleph, Gary J. Grover, Thomas A. Hess, Albert J. D'Alonzo, Raymond B. Darbenzio, Joseph C. Sewter, S Dzwonczyk, Jia L. Zhu
Publikováno v:
European Journal of Pharmacology. 272:269-278
The antiarrhythmic effects of vehicle (0.1% dimethyl sulfoxide: DMSO) or capsaicin were evaluated in isolated perfused rat and guinea pig heart preparations. In the rat, capsaicin reduced ischemic ventricular tachycardia from 100% in control to 0%, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34cc274b864c77c2f5c0b312650f6563
https://doi.org/10.1016/0014-2999(94)00653-o
https://doi.org/10.1016/0014-2999(94)00653-o
Autor:
Jia L. Zhu, R. J. Leadley
Publikováno v:
Experimental Biology and Medicine. 202:217-224
Infusion of norepinephrine (NE) into humans and experimental animals induces diuresis by mechanisms that are not completely understood. Two series of experiments were performed to determine whether changes in plasma levels of vasopressin or changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4492c8704189f50bb4153fa2d2573455
https://doi.org/10.3181/00379727-202-43530
https://doi.org/10.3181/00379727-202-43530
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 62:e18-e19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4376b3344a906a6a63b34fd15206d6aa
https://doi.org/10.1016/j.vascn.2010.11.063
https://doi.org/10.1016/j.vascn.2010.11.063
Publikováno v:
European journal of pharmacology. 369(1)
Acquired long QT syndrome develops as a result of pharmacological interventions that prolong action potential duration. Excessive action potential prolongation may lead to torsade de pointes, a potentially fatal arrhythmia. To study this arrhythmia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d391346ef6a07edeeae2b6041ff8c7f
https://pubmed.ncbi.nlm.nih.gov/10204682
https://pubmed.ncbi.nlm.nih.gov/10204682
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 60:243
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28bc6a2b6e615e36302cc5d5a21bda4f
https://doi.org/10.1016/j.vascn.2009.04.138
https://doi.org/10.1016/j.vascn.2009.04.138
Publikováno v:
Life sciences. 46(2)
This study was designed to determine whether the increase in atriopeptin secretion induced by an intravenous infusion of norepinephrine is mediated directly by adrenergic receptor stimulation or indirectly by the associated increase in atrial pressur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fd3b8f721a937a2c32244955ad9f34
https://pubmed.ncbi.nlm.nih.gov/2137190
https://pubmed.ncbi.nlm.nih.gov/2137190
Autor:
Jia L. Zhuo, Xiao C. Li
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 9 (2019)
See Article Kemp et al
Externí odkaz:
https://doaj.org/article/5b94fae2f5d841f79ded59cc88428cc2