Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jia Jun Chia"'
Autor:
Sheli R. Radoshitzky, Patrick Iversen, Xianghan Lu, Jing Zou, Suzanne J. F. Kaptein, Kelly S. Stuthman, Sean A. Van Tongeren, Jesse Steffens, Ruoyu Gong, Hoa Truong, Annapurna A. Sapre, Huiling Yang, Xiaodong Xie, Jia Jun Chia, Zhijuan J. Song, Stacey M. Leventhal, Josolyn Chan, Alex Shornikov, Xin Zhang, David Cowfer, Helen Yu, Travis Warren, Tomas Cihlar, Danielle P. Porter, Johan Neyts, Pei-Yong Shi, Jay Wells, John P. Bilello, Joy Y. Feng
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Remdesivir (GS-5734; VEKLURY) is a single diastereomer monophosphoramidate prodrug of an adenosine analog (GS-441524). Remdesivir is taken up by target cells and metabolized in multiple steps to form the active nucleoside triphosphate (GS-44
Externí odkaz:
https://doaj.org/article/ee7f5fe788f0477a9009a8f32e4eeffd
Autor:
Cecilia M. Giachelli, Suhaib Borgeia, Mary C. Wallingford, Timothy C. Cox, Chenphop Sawangmake, Jia Jun Chia, Elizabeth M. Leaf, Kenneth I. Marro, Nicholas W. Chavkin, Mei Y. Speer
Publikováno v:
Brain Pathology. 27:64-76
Idiopathic basal ganglia calcification is a brain calcification disorder that has been genetically linked to autosomal dominant mutations in the sodium-dependent phosphate co-transporter, SLC20A2. The mechanisms whereby deficiency of Slc20a2 leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c763bcfd585e567531ff009e510332a
https://doi.org/10.1111/bpa.12362
https://doi.org/10.1111/bpa.12362
Autor:
Shunsuke Yamada, Jia Jun Chia, Cecilia M. Giachelli, Mei Y. Speer, Elizabeth M. Leaf, Timothy C. Cox
Publikováno v:
Kidney international. 94(4)
PiT-2, a type III sodium-dependent phosphate transporter, is a causative gene for the brain arteriolar calcification in people with familial basal ganglion calcification. Here we examined the effect of PiT-2 haploinsufficiency on vascular calcificati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf8e838a15c4a4f84153cb6815ebf00
https://pubmed.ncbi.nlm.nih.gov/30243309
https://pubmed.ncbi.nlm.nih.gov/30243309
Vascular calcification (VC) is prevalent in chronic kidney disease and elevated serum inorganic phosphate (Pi) is a recognized risk factor. The type III sodium-dependent phosphate transporter, PiT-1, is required for elevated Pi-induced osteochondroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced6bef09ae4249c36b4607be83529ef
https://europepmc.org/articles/PMC4387109/
https://europepmc.org/articles/PMC4387109/
Autor:
Radoshitzky, Sheli R.1,2 (AUTHOR), Iversen, Patrick1 (AUTHOR), Lu, Xianghan3 (AUTHOR), Zou, Jing4 (AUTHOR), Kaptein, Suzanne J. F.5,6 (AUTHOR), Stuthman, Kelly S.1 (AUTHOR), Van Tongeren, Sean A.1 (AUTHOR), Steffens, Jesse1 (AUTHOR), Gong, Ruoyu3 (AUTHOR), Truong, Hoa3 (AUTHOR), Sapre, Annapurna A.3 (AUTHOR), Yang, Huiling3 (AUTHOR), Xie, Xiaodong3 (AUTHOR), Chia, Jia Jun3 (AUTHOR), Song, Zhijuan J.3 (AUTHOR), Leventhal, Stacey M.3 (AUTHOR), Chan, Josolyn3 (AUTHOR), Shornikov, Alex3 (AUTHOR), Zhang, Xin5,6 (AUTHOR), Cowfer, David3 (AUTHOR)
Publikováno v:
Scientific Reports. 2/23/2023, Vol. 13 Issue 1, p1-13. 13p.
Autor:
Hyrina, Anastasia1 (AUTHOR) anastasia.hyrina@gilead.com, Burdette, Dara1 (AUTHOR), Song, Zhijuan1 (AUTHOR), Ramirez, Ricardo1 (AUTHOR), Okesli-Armlovich, Ayse1 (AUTHOR), Vijayakumar, Archana1 (AUTHOR), Bates, Jamie1 (AUTHOR), Trevaskis, James L.1 (AUTHOR), Fletcher, Simon P.1 (AUTHOR), Lee, William A.1 (AUTHOR), Holdorf, Meghan M.1 (AUTHOR)
Publikováno v:
PLoS ONE. 8/4/2022, Vol. 17 Issue 8, p1-19. 19p.
Publikováno v:
Biophysical Journal. (3):122a
Actin filaments serve as structural elements of the cytoskeleton subject to mechanical forces and provide binding sites for actin-binding proteins (ABPs). Structural studies have established that actin filaments can adopt several different twist stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33963feb53203b9d2a4a32caf39ce8d
Autor:
Wallingford, Mary Catherine, Chia, Jia Jun, Leaf, Elizabeth M., Borgeia, Suhaib, Chavkin, Nicholas W., Sawangmake, Chenphop, Marro, Ken, Cox, Timothy C., Speer, Mei Y., Giachelli, Cecilia M.
Publikováno v:
Brain Pathology; Jan2017, Vol. 27 Issue 1, p64-76, 13p
Publikováno v:
Medical Letter on the CDC & FDA; 4/4/2023, p610-610, 1p
Autor:
Risca, Viviana I., Wang, Evan B., Chaudhuri, Ovijit, Chia, Jia Jun, Geissler, Phillip L., Fletcher, Daniel A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/21/2012, Vol. 109 Issue 8, p2913-2918, 6p