Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jia Huan Lu"'
Autor:
Zhao‐lei Zeng, Jia‐huan Lu, Yun Wang, Hui Sheng, Ying‐nan Wang, Zhan‐hong Chen, Qi‐nian Wu, Jia‐Bo Zheng, Yan‐xing Chen, Dong‐dong Yang, Kai Yu, Hai‐yu Mo, Jia‐jia Hu, Pei‐shan Hu, Ze‐xian Liu, Huai‐qiang Ju, Rui‐Hua Xu
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2423-2441 (2021)
Abstract Background Numerous reports on microRNAs have illustrated their role in tumor growth and metastasis. Recently, a new prognostic factor, miR‐125b‐2‐3p, has been identified for predicting chemotherapeutic sensitivity in advanced colorect
Externí odkaz:
https://doaj.org/article/39ec1ebf35c944a5aefe92e4611f5aa4
Autor:
Yun Wang, Jia-Huan Lu, Qi-Nian Wu, Ying Jin, De-Shen Wang, Yan-Xing Chen, Jia Liu, Xiao-Jing Luo, Qi Meng, Heng-Ying Pu, Ying-Nan Wang, Pei-Shan Hu, Ze-Xian Liu, Zhao-Lei Zeng, Qi Zhao, Rong Deng, Xiao-Feng Zhu, Huai-Qiang Ju, Rui-Hua Xu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-18 (2019)
Abstract Background Long noncoding RNAs (lncRNAs) play nonnegligible roles in the epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that promotes the colorectal cancer (CRC) progression and could be a potential the
Externí odkaz:
https://doaj.org/article/cd254d1cc795495d9725359a49bd532b
Autor:
Zhan-Hong Chen, Jing-Jing Qi, Qi-Nian Wu, Jia-Huan Lu, Ze-Xian Liu, Yun Wang, Pei-Shan Hu, Ting Li, Jin-Fei Lin, Xiang-Yuan Wu, Lei Miao, Zhao-Lei Zeng, Dan Xie, Huai-Qiang Ju, Rui-Hua Xu, Feng Wang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-18 (2019)
Abstract Background Deregulation of protein translation control is a hallmark of cancers. Eukaryotic initiation factor 4A2 (EIF4A2) is required for mRNA binding to ribosome and plays an important role in translation initiation. However, little is kno
Externí odkaz:
https://doaj.org/article/4898116ca4344a52a40623baf9ce1d26
Autor:
Dong-Dong Yang, Zhan-Hong Chen, Kai Yu, Jia-Huan Lu, Qi-Nian Wu, Yun Wang, Huai-Qiang Ju, Rui-Hua Xu, Ze-Xian Liu, Zhao-Lei Zeng
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Methyltransferase-like 3 (METTL3), a major component of the N6-methyladenosine (m6A) methyltransferase complex, has been suggested to function as an oncogene in several cancers. However, its biological mechanism and the involved pathways in gastric c
Externí odkaz:
https://doaj.org/article/320f703d43ae4cefad4ebf15a5cd3738
Autor:
Yan-Xing Chen, Huai-Qiang Ju, Zhan-Hong Chen, Jia-jia Hu, Rui-Hua Xu, Ying-Nan Wang, Jia-huan Lu, Hui Sheng, Yun Wang, Kai Yu, Pei-Shan Hu, Zexian Liu, Jia-Bo Zheng, Hai-Yu Mo, Qi-Nian Wu, Dong-dong Yang, Zhao-Lei Zeng
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2423-2441 (2021)
Cancer Medicine
Cancer Medicine
Background Numerous reports on microRNAs have illustrated their role in tumor growth and metastasis. Recently, a new prognostic factor, miR‐125b‐2‐3p, has been identified for predicting chemotherapeutic sensitivity in advanced colorectal cancer
Autor:
Jia-huan Lu, De Shen Wang, Zexian Liu, Huai-Qiang Ju, Yun-Xin Lu, Zhao-Lei Zeng, Ming-Ming He, Hong-En Yu, Qi Zhao, Yan-Xing Chen, Qi-Nian Wu, Zhan-Hong Chen, Yun Wang, Feng Wang, Ying-Nan Wang, Rui-Hua Xu, Jia Liu, Hui Sheng
Publikováno v:
Cancer Letters. 473:74-89
Gastrointestinal cancer causes countless deaths every year due to therapeutic resistance. However, whether metabolic alterations contribute to chemoresistance is not well understood. In this study, we report that fatty acid (FA) catabolism was activa
Publikováno v:
Journal of Cancer
Background: The aim of our research was to assess the prognostic value of the apolipoprotein B (ApoB) to apolipoprotein A-I (ApoA-I) ratio (ApoB/ApoA-I) in metastatic colorectal cancer (mCRC) patients. Methods: We randomly assigned 838 patients into
Autor:
Rong Deng, Ying Nan Wang, Yan Xing Chen, Xiao Feng Zhu, Pei Shan Hu, Heng Ying Pu, Xiao Jing Luo, Zexian Liu, Huai-Qiang Ju, De Shen Wang, Rui-Hua Xu, Qi Meng, Qi Nian Wu, Yun Wang, Zhao Lei Zeng, Qi Zhao, Ying Jin, Jia Huan Lu, Jia Liu
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-18 (2019)
Molecular Cancer
Molecular Cancer
BackgroundLong noncoding RNAs (lncRNAs) play nonnegligible roles in the epigenetic regulation of cancer cells. This study aimed to identify a specific lncRNA that promotes the colorectal cancer (CRC) progression and could be a potential therapeutic t
Publikováno v:
Abstracts.
Background The human ERBB receptor tyrosine kinase family is deregulated in multiple cancer types either through amplification or mutations. The ERBB4 mutation of gastric cancer (GC) is listed as the top 2 alteration frequency, which was around 10%.
Autor:
Dan Xie, Qi Zhao, Yang W. Shao, Yun Xin Lu, Jia Huan Lu, Zhi Qiang Wang, Yu Hong Li, Zexian Liu, Cai Yun He, Miao Zhen Qiu, De Shen Wang, Feng Wang, Feng Hua Wang, Xiao Nan Wang, Wei Hua Jia, Rui-Hua Xu, Xue Wu, Hua Bao, Zhao Lei Zeng, Zekun Liu
Publikováno v:
Gut. 68:1152-1161
ObjectiveTo monitor trastuzumab resistance and determine the underlying mechanisms for the limited response rate and rapid emergence of resistance of HER2+ metastatic gastric cancer (mGC).DesignTargeted sequencing of 416 clinically relevant genes was