Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Jia Bei Wang"'
Autor:
Qing-Hai Zhang, Jia-Bei Wang
Publikováno v:
Ecological Indicators, Vol 166, Iss , Pp 112277- (2024)
Multi-functional coupling evaluation of land use is the basis of rural land use coordination and allocation, and it is the key to determine the inherent function combination pattern of urban land use and the dynamic trade-offs between functions, whic
Externí odkaz:
https://doaj.org/article/2123b0f158b44843bfc07bf2c1a5853b
UBE2O reduces the effectiveness of interferon-α via degradation of IFIT3 in hepatocellular carcinoma
Autor:
Heng Li, Yao Liu, Can Cheng, Yang Wu, Shu-Hang Liang, Liang Wu, Hong Wang, Cong-yin Tu, Han-Hui Yao, Fan-Zheng Meng, Bo Zhang, Wei Wang, Jia-Bei Wang, Lian-Xin Liu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract Interferon (IFN) exerts its effects through interferon-stimulated genes (ISGs), but its efficacy is limited by interferon resistance, which can be caused by the ubiquitination of key proteins. UBE2O was initially identified as a promising th
Externí odkaz:
https://doaj.org/article/0f082dbe20984c66a39ca29f43399611
Autor:
Hao Wang, Wei Wei, Zhong-Yuan Zhang, Yao Liu, Bin Shi, Wen Zhong, Hou-Shun Zhang, Xin Fang, Chun-Lei Sun, Jia-Bei Wang, Lian-Xin Liu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-13 (2021)
Abstract Metastasis remains the major obstacle to improved survival for colorectal cancer (CRC) patients. Dysregulation of N6-methyladenosine (m6A) is causally associated with the development of metastasis through poorly understood mechanisms. Here,
Externí odkaz:
https://doaj.org/article/997ae3bbc9274d988932b75c2386616a
Publikováno v:
OncoTargets and therapy
Immune-modulatory therapy, especially with immune-checkpoint inhibitors (ICIs), has reshaped cancer therapeutics. Immunotherapy is relatively a novel approach that can effectively delay the progression of aggressive tumors and inhibit tumor recurrenc
Autor:
Fang Liu, Robert W. Buchanan, Brianne Redman, MacKenzie A. Sayer, Stephen W. Hoag, Gopal Vyas, Jia Bei Wang, James M. Gold, Jingtao Wang, Daniela Cihakova, Heidi J. Wehring, David A. Gorelick, Deanna L. Kelly, Olga Y Ponomareva, Shuo Chen, Monica V. Talor, Charles M. Richardson
Publikováno v:
Schizophrenia Bulletin Open. 1
Schizophrenia is a complex mental illness characterized by positive and negative symptoms. Antipsychotic medications are the main treatment for this condition; however, many patients have only a partial response. All currently available antipsychotic
Autor:
Yi Ting Chiu, Zheng-Xiong Xi, Yi He, Jia Zhan, Jia Bei Wang, Lee-Yuan Liu-Chen, Xiao-Fei Wang, Bo Feng, Guo Hua Bi, Hai Ying Zhang, Elisabeth Barbier
Publikováno v:
The Journal of Neuroscience. 36:10392-10403
The etiology and pathophysiology underlying opioid tolerance and dependence are still unknown. Because mu opioid receptor (MOR) plays an essential role in opioid action, many vulnerability-related studies have focused on single nucleotide polymorphis
Autor:
Matthew Glassman, Sagar Shukla, Moshe Honick, Ann Marie Kearns, Jia Bei Wang, Deanna L. Kelly, David A. Gorelick, Robert P. McMahon, Ken Bauer, Hazem E. Hassan, Heidi J. Wehring, Mingming Yu, Stephanie Feldman, Ahmed Ibrahim
Publikováno v:
The Journal of Clinical Pharmacology. 57:151-160
Cocaine use disorder (CUD) remains a significant public health challenge. l-Tetrahydropalmatine (l-THP), a well-tolerated and nonaddictive compound, shows promise for the management of CUD. Its pharmacologic profile includes blockade at dopamine and
Autor:
Chengge Gao, Jia-bei Wang, You-ping Liu, Zheng Chu, Xiancang Ma, Yonghui Dang, Peng Liu, Rui Ma
Publikováno v:
Neuroscience Letters. 607:40-45
Social isolation (SI) rearing has been demonstrated to induce behavioral abnormalities like anxiety, impulsivity, aggression, and learning and memory deficits which are relevant to core symptoms in patients with some certain neuropsychiatric disorder
Publikováno v:
Brain Research. 1622:196-203
Previous studies have implicated a role of the histidine triad nucleotide-binding protein 1 (Hint1) in the pathogenesis of schizophrenia. Protein kinase C gamma (PKCγ) could be potentially involved in the Hint1-implicated pathogenesis since PKCγ wa
Publikováno v:
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 39(5)
The histidine triad nucleotide binding protein1(HINT1),which belongs to the histidine triad(HIT) enzyme superfamily,exerts its enzymic activities as hydrolase or transferase. Its physiological functions are still unclear. HINT1 protein is expressed i