Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jia Bao Pan"'
Publikováno v:
American Journal of Physiology: Endocrinology & Metabolism; Dec2019, Vol. 317 Issue 6, pE1158-E1171, 14p, 7 Graphs
Autor:
Jorge D. Brioni, Kaitlin E. Browman, Victoria A. Komater, Robert B. Moreland, Angela L. Molesky, Jia Bao Pan, Gerard B. Fox, Peter Curzon, Michael W. Decker
Publikováno v:
Pharmacology Biochemistry and Behavior. 82:148-155
The recent development of a highly selective dopamine D4 receptor agonist, A-412997 (2-(3',4',5',6'-tetrahydro-2'H-[2,4'] bipyridinyl-1'-yl)-N-m-tolyl-acetamide), has provided a pharmacological tool with which to conduct systematic investigations int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f0d8e43ecd919ead3382af010071b3
https://doi.org/10.1016/j.pbb.2005.08.002
https://doi.org/10.1016/j.pbb.2005.08.002
Autor:
Lynne E. Rueter, Gerard B. Fox, Kaitlin E. Browman, Arthur A. Hancock, Ramin Faghih, Timothy A. Esbenshade, Jill M. Wetter, Richard J. Radek, Min Zhang, James P. Sullivan, Michael J. Buckley, Kennan C. Marsh, Victoria A. Komater, Jia Bao Pan, Holly M. Miner, Martine Lemaire, Betty B. Yao, Kathleen M. Krueger, Roger D. Porsolt, Michael E. Ballard, Karla Drescher, Marlon D. Cowart, Michael W. Decker, Youssef L. Bennani, R. Scott Bitner
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 313:176-190
Acute pharmacological blockade of central histamine H 3 receptors (H 3 Rs) enhances arousal/attention in rodents. However, there is little information available for other behavioral domains or for repeated administration using selective compounds. AB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049fafd42106c95c055411dd6cda767b
https://doi.org/10.1124/jpet.104.078402
https://doi.org/10.1124/jpet.104.078402
Autor:
Gerard B. Fox, Youssef L. Bennani, Ramin Faghih, Kathy M. Krueger, Michael P. Curtis, Arthur A. Hancock, Jia Bao Pan, Marlon D. Cowart, Timothy A. Esbenshade, Wesley J. Dwight, Thomas G. Pagano, John K. Pratt
Publikováno v:
Archiv der Pharmazie. 337:219-229
Structure-activity relationships of homopiperazine-containing alkoxybiaryl nitriles employing various D-amino acid moieties and their N-furanoyl analogues were undertaken. This led to A-320436, a potent and selective non-imidazole H(3)-receptor antag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f767412e9a033ad679e15615d9ac5b2
https://doi.org/10.1002/ardp.200300844
https://doi.org/10.1002/ardp.200300844
Autor:
Betty B. Yao, Ramin Faghih, Thomas R. Miller, Henry Zhang, Youssef L. Bennani, Timothy A. Esbenshade, David G. Witte, Gregory A. Gfesser, Gerard B. Fox, Jia Bao Pan, Arthur A. Hancock, Chae-Hee Kang, Jürgen Dinges, Kathy M. Krueger
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:673-676
Further SAR studies on novel histamine H(3) receptor antagonists are presented. Compound 14bb is a potent antagonist of both the rat cortical and human clone receptors, and is demonstrated to act functionally as an antagonist in an in vivo mouse dips
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed226c898efdb95d448246274d9c2d1
https://doi.org/10.1016/j.bmcl.2003.11.038
https://doi.org/10.1016/j.bmcl.2003.11.038
Autor:
Kennan C. Marsh, Wesley J. Dwight, Arthur A. Hancock, Jill M. McVey, Jia Bao Pan, Ramin Faghih, Kathy M. Krueger, Youssef L. Bennani, Gerard B. Fox, Timothy A. Esbenshade
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:1325-1328
Novel 4′-[(NR1R2-1-yl)]-propoxy-biaryl-4-carboxamides were designed and synthesized. All compounds were tested for affinity at histamine H 3 receptors. Most compounds were highly potent and selective for human and rat H 3 receptors and selected exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a320ca39430445fdcf92976a2bd7854
https://doi.org/10.1016/s0960-894x(03)00118-5
https://doi.org/10.1016/s0960-894x(03)00118-5
Autor:
Betty B. Yao, Ramin Faghih, Michael W. Decker, Youssef L. Bennani, Gerard B. Fox, Richard J. Radek, Timothy A. Esbenshade, R. Scott Bitner, Michael Williams, Arthur A. Hancock, Angela M. Lewis, Jia Bao Pan
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:897-908
Pharmacological blockade of central histamine H3 receptors (H3Rs) enhances cognition in rodents and offers promise for the clinical treatment of neurological disorders. However, many previously characterized H3R antagonists are either not selective f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f7742a26e897f408bb4e6ae5ee97b6
https://doi.org/10.1124/jpet.102.047241
https://doi.org/10.1124/jpet.102.047241
Autor:
Arthur A. Hancock, Youssef L. Bennani, Gerard B. Fox, Chae Hee Kang, R. Scott Bitner, Arthur L. Nikkel, Michael W. Decker, Ramin Faghih, Lawrence A. Black, Timothy A. Esbenshade, Thomas R. Miller, Jia Bao Pan
Publikováno v:
Pharmacology Biochemistry and Behavior. 72:741-750
The selective H(3) receptor agonist (R)-alpha-methylhistamine [(R)-alpha-MeHA] stimulates drinking in the adult rat. In the present study, we investigated the role of the H(3) receptor in mediating this behavior in a new dipsogenia model using the CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91f7c5913804e63eb62da794fb32b54
https://doi.org/10.1016/s0091-3057(02)00745-1
https://doi.org/10.1016/s0091-3057(02)00745-1
Autor:
Gerard B. Fox, Lawrence A. Black, Timothy A. Esbenshade, Youssef L. Bennani, Arthur A. Hancock, Ramin Faghih, Jia Bao Pan, Michael W. Decker
Publikováno v:
Behavioural Brain Research. 131:151-161
Histamine H(3) receptor antagonists have been proposed as potentially useful therapeutic agents for the treatment of several disorders including attention deficit, schizophrenia, depression, and Alzheimer's disease. We have developed a repeated acqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f077438fd8eab034e658541fff8db85a
https://doi.org/10.1016/s0166-4328(01)00379-5
https://doi.org/10.1016/s0166-4328(01)00379-5
Publikováno v:
Molecular Brain Research. 18:259-266
Alzheimer's disease and cognitive impairment in rats has been associated with an increase in the percentage of amyloid precursor protein (APP) containing the KPI domain. It has recently been reported that retinoic acid (RA) is capable of increasing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3ca63054e84bac6d5471c331850a28
https://doi.org/10.1016/0169-328x(93)90198-x
https://doi.org/10.1016/0169-328x(93)90198-x