Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jia‐Wen Mo"'
Autor:
Jia‐Wen Mo, Peng‐Li Kong, Li Ding, Jun Fan, Jing Ren, Cheng‐Lin Lu, Fang Guo, Liang‐Yu Chen, Ran Mo, Qiu‐Ling Zhong, You‐Lu Wen, Ting‐Ting Gu, Qian‐Wen Wang, Shu‐Ji Li, Ting Guo, Tian‐Ming Gao, Xiong Cao
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract Lysosomes are important cellular structures for human health as centers for recycling, signaling, metabolism and stress adaptation. However, the potential role of lysosomes in stress‐related emotions has long been overlooked. Here, it is f
Externí odkaz:
https://doaj.org/article/1cd74eec8301438b9b272bb2dbafc826
Autor:
Fang Guo, Jun Fan, Jin-Ming Liu, Peng-Li Kong, Jing Ren, Jia-Wen Mo, Cheng-Lin Lu, Qiu-Ling Zhong, Liang-Yu Chen, Hao-Tian Jiang, Canyuan Zhang, You-Lu Wen, Ting-Ting Gu, Shu-Ji Li, Ying-Ying Fang, Bing-Xing Pan, Tian-Ming Gao, Xiong Cao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Epigenetic mechanisms bridge genetic and environmental factors that contribute to the pathogenesis of major depression disorder (MDD). However, the cellular specificity and sensitivity of environmental stress on brain epitranscriptomics and
Externí odkaz:
https://doaj.org/article/52285e6b4db94e20938dae6bcf0b2c81
Autor:
Jun Fan, Fang Guo, Ran Mo, Liang-Yu Chen, Jia-Wen Mo, Cheng-Lin Lu, Jing Ren, Qiu-Ling Zhong, Xiao-Jing Kuang, You-Lu Wen, Ting-Ting Gu, Jin-Ming Liu, Shu-Ji Li, Ying-Ying Fang, Cunyou Zhao, Tian-Ming Gao, Xiong Cao
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Major depressive disorder is a common and devastating psychiatric disease, and the prevalence and burden are substantially increasing worldwide. Multiple studies of depression patients have implicated glucose metabolic dysfunction in the pathophysiol
Externí odkaz:
https://doaj.org/article/d46ca8f5b3d74b3b907284b7ec8a1efe
Autor:
Jun Fan, Qiu-Ling Zhong, Ran Mo, Cheng-Lin Lu, Jing Ren, Jia-Wen Mo, Fang Guo, You-Lu Wen, Xiong Cao
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
The medial prefrontal cortex (mPFC), a key part of the brain networks that are closely related to the regulation of behavior, acts as a key regulator in emotion, social cognition, and decision making. Astrocytes are the majority cell type of glial ce
Externí odkaz:
https://doaj.org/article/9341dd5066144fe59e6c2119a90df68f
Autor:
Jing Ren, Cheng-Lin Lu, Jie Huang, Jun Fan, Fang Guo, Jia-Wen Mo, Wei-Yuan Huang, Peng-Li Kong, Xiao-Wen Li, Li-Rong Sun, Xiang-Dong Sun, Xiong Cao
Publikováno v:
J Neurosci
Anxiety disorders are debilitating psychiatric diseases that affect ∼16% of the world's population. Although it has been proposed that the central nucleus of the amygdala (CeA) plays a role in anxiety, the molecular and circuit mechanisms through w
Autor:
Jiaming Liu, Jia-Wen Mo, Xunda Wang, Ziqi An, Shuangyang Zhang, Can-Yuan Zhang, Peiwei Yi, Alex T. L. Leong, Jing Ren, Liang-Yu Chen, Ran Mo, Yuanyao Xie, Qianjin Feng, Wufan Chen, Tian-Ming Gao, Ed X. Wu, Yanqiu Feng, Xiong Cao
Publikováno v:
Science advances. 8(46)
Major depressive disorder (MDD) is a devastating mental disorder that affects up to 17% of the population worldwide. Although brain-wide network-level abnormalities in MDD patients via resting-state functional magnetic resonance imaging (rsfMRI) exis
Autor:
Cheng-Lin Lu, Jing Ren, Jia-Wen Mo, Jun Fan, Fang Guo, Liang-Yu Chen, You-Lu Wen, Shu-Ji Li, Ying-Ying Fang, Zhao-Fa Wu, Yu-Long Li, Tian-Ming Gao, Xiong Cao
Publikováno v:
Biological psychiatry. 92(3)
Major depressive disorder is a devastating psychiatric illness that affects approximately 17% of the population worldwide. Astrocyte dysfunction has been implicated in its pathophysiology. Traumatic experiences and stress contribute to the onset of m