Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jia‐Kun Xu"'
Autor:
Xi‐Xi Li, Jia‐Kun Xu, Wei‐Jie Su, Hong‐Lin Wu, Kun Zhao, Chang‐Ming Zhang, Xiang‐Kun Chen, Li‐Xuan Yang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 2, Pp 161-174 (2024)
Abstract Temozolomide (TMZ) resistance presents a significant challenge in the treatment of gliomas. Although lysine demethylase 4A (KDM4A) has been implicated in various cancer‐related processes, its role in TMZ resistance remains unclear. This st
Externí odkaz:
https://doaj.org/article/c53c18a5173743f79d4628eec81121c0
Autor:
Yu-Ting Ling, Qian-Qian Guo, Si-Min Wang, Li-Nan Zhang, Jin-Hua Chen, Yi Liu, Ruo-Heng Xuan, Bo Qu, Li-Ge Liu, Zhi-Shuang Wen, Jia-Kun Xu, Lu-Lu Jiang, Wen-Biao Xian, Bin Wu, Chang-Ming Zhang, Ling Chen, Jin-Long Liu, Nan Jiang
Publikováno v:
Parkinson's Disease, Vol 2022 (2022)
Introduction. Postoperative delirium can increase cognitive impairment and mortality in patients with Parkinson’s disease. The purpose of this study was to develop and internally validate a clinical prediction model of delirium after deep brain sti
Externí odkaz:
https://doaj.org/article/84d598ae4bda4784a17d5ea6555ac025
Publikováno v:
Entropy, Vol 25, Iss 1, p 128 (2023)
Irreversible entropy production (IEP) plays an important role in quantum thermodynamic processes. Here, we investigate the geometrical bounds of IEP in nonequilibrium thermodynamics by exemplifying a system coupled to a squeezed thermal bath subject
Externí odkaz:
https://doaj.org/article/c86742801bfc4ca6ba1ca91e8480c62a
Publikováno v:
Molecules, Vol 27, Iss 24, p 8660 (2022)
Tetracyclines are one class of widely used antibiotics. Meanwhile, due to abuse and improper disposal, they are often detected in wastewater, which causes a series of environmental problems and poses a threat to human health and safety. As an efficie
Externí odkaz:
https://doaj.org/article/de63671967994497ac3e156478dcb852
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The conversion of Kraft lignin in plant biomass into renewable chemicals, aiming at harvesting aromatic compounds, is a challenge process in biorefinery. Comparing to the traditional chemical methods, enzymatic catalysis provides a gentle way for the
Externí odkaz:
https://doaj.org/article/07f697122e6e48e2979fb3a150d611bf
Publikováno v:
Molecules, Vol 19, Iss 12, Pp 21506-21528 (2014)
During the past few years, nanoparticles have been used for various applications including, but not limited to, protein immobilization, bioseparation, environmental treatment, biomedical and bioengineering usage, and food analysis. Among all types of
Externí odkaz:
https://doaj.org/article/dce0424236d6413f976e764ef7edc5c5
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 12, Pp m1574-m1574 (2010)
In the title compound, [Ni(C14H8O5)(C10H8N2)]n, the NiII atom is six-coordinated in a slightly distorted octahedral geometry by four O atoms from two chelating carboxylate groups of symmetry-related 2,4′-oxydibenzoate anions and by two N atoms from
Externí odkaz:
https://doaj.org/article/afa736d64a374bda8c618d8c7c243f18
Publikováno v:
Molecular Systems Design & Engineering. 7:239-247
Human neuroglobin (Ngb) was rationally engineered into an enzyme by triple mutations, A15C/H64D/F49Y Ngb, which efficiently catalyzes the synthesis of indigo and derivatives with different colors for textile dyeing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaccbee44cf04493ffd6452277ea821c
https://doi.org/10.1039/d1me00123j
https://doi.org/10.1039/d1me00123j
Autor:
Li-Juan Sun, Ge-Bo Wen, Ying-Wu Lin, Xiangshi Tan, Hong Yuan, Jia-Kun Xu, Jia-Jia Lang, Jie Luo
Publikováno v:
Biochemistry. 62:369-377
The design of functional metalloenzymes is attractive for the biosynthesis of biologically important compounds, such as phenoxazinones and phenazines catalyzed by native phenoxazinone synthase (PHS). To design functional heme enzymes, we used myoglob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3010954d0d29c2ea308eefa92b1a46
https://doi.org/10.1021/acs.biochem.1c00554
https://doi.org/10.1021/acs.biochem.1c00554
Publikováno v:
Inorganic Chemistry. 60:2839-2845
Protein design has received much attention in the last decades. With an additional disulfide bond to enhance the protein stability, human A15C neuroglobin (Ngb) is an ideal protein scaffold for heme enzyme design. In this study, we rationally convert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6787e682debe8130d1904417040bcd6
https://doi.org/10.1021/acs.inorgchem.0c03777
https://doi.org/10.1021/acs.inorgchem.0c03777