Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Jia‐Guo Zhou"'
Autor:
Zhi-Wei Mo, Yue-Ming Peng, Yi-Xin Zhang, Yan Li, Bi-Ang Kang, Ya-Ting Chen, Le Li, Mary G. Sorci-Thomas, Yi-Jun Lin, Yang Cao, Si Chen, Ze-Long Liu, Jian-Jun Gao, Zhan-Peng Huang, Jia-Guo Zhou, Mian Wang, Guang-Qi Chang, Meng-Jie Deng, Yu-Jia Liu, Zhen-Sheng Ma, Zuo-Jun Hu, Yu-Gang Dong, Zhi-Jun Ou, Jing-Song Ou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Normal high-density lipoprotein (nHDL) can induce angiogenesis in healthy individuals. However, HDL from patients with coronary artery disease undergoes various modifications, becomes dysfunctional (dHDL), and loses its ability to promote an
Externí odkaz:
https://doaj.org/article/bfb20196431147a69293901f5d16f853
MiR-302a Limits Vascular Inflammation by Suppressing Nuclear Factor-κ B Pathway in Endothelial Cells
Autor:
Jia-Ni Yuan, Yu Hong, Zhuo-Lin Ma, Rui-Ping Pang, Qing-Qing Lei, Xiao-Fei Lv, Jia-Guo Zhou, Hui Huang, Ting-Ting Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The inflammatory response of endothelial cells accelerates various vascular diseases. MicroRNAs (miRNAs) participate in diverse cellular processes during inflammation. In the present study, we found that miR-302a is an effective suppressor of vascula
Externí odkaz:
https://doaj.org/article/039e74cdf1f94b17808ba2b883dc4a3f
Autor:
Jia‐Wei Guo, Xiu Liu, Ting‐Ting Zhang, Xiao‐Chun Lin, Yu Hong, Jie Yu, Qin‐Yan Wu, Fei‐Ran Zhang, Qian‐Qian Wu, Jin‐Yan Shang, Xiao‐Fei Lv, Jing‐Song Ou, Jia‐Guo Zhou, Rui‐Ping Pang, Bao‐Dong Tang, Si‐Jia Liang
Publikováno v:
Advanced Science, Vol 7, Iss 10, Pp n/a-n/a (2020)
Abstract Nonalcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver disease, and the mechanisms underpinning its pathogenesis have not been completely established. Transmembrane member 16A (TMEM16A), a component of the Ca2+
Externí odkaz:
https://doaj.org/article/bae1b668ea3c4065964c2acee735b573
Autor:
Ting-Ting Zhang, Qing-Qing Lei, Jie He, Xin Guan, Xin Zhang, Ying Huang, Zi-Yue Zhou, Rui-Xin Fan, Ting Wang, Chen-Xi Li, Jin-Yan Shang, Zhuo-Miao Lin, Wan-Li Peng, Li-Kai Xia, Yu-Ling He, Chuan-Ying Hong, Jing-Song Ou, Rui-Ping Pang, Xiao-Ping Fan, Hui Huang, Jia-Guo Zhou
Publikováno v:
Circulation.
BACKGROUND: Aortic dissection (AD) is a fatal cardiovascular disorder without effective medications due to unclear pathogenic mechanisms. Bestrophin3 (Best3), the predominant isoform of bestrophin family in vessels, has emerged as critical for vascul
Autor:
Jie Yu, Su-Yue He, Si-Jia Liang, Jia-wei Guo, Zhao-Qiang Li, Wan-Li Peng, Yong-Hua Tuo, Jia-Guo Zhou, Ying Ouyang, Xiaofei Lv, Xiu Liu, Jing-Song Ou, Xiao-Chun Lin, An-Dong Zhou, Jian-Xin Sun, Jin-Yan Shang, Ming-Ming Ma, Fei-Ran Zhang, Rui-Ping Pang, Cheng Wang, Yan-Chen Ye
Publikováno v:
Eur Heart J
Aims Our previous study demonstrated that Ca2+ influx through the Orai1 store-operated Ca2+ channel in macrophages contributes to foam cell formation and atherosclerosis via the calcineurin–ASK1 pathway, not the classical calcineurin–nuclear fact
Publikováno v:
Acta Pharmacol Sin
The excessive proliferation and migration of smooth muscle cells (SMCs) play an important role in restenosis following percutaneous coronary interventions. MicroRNAs are able to target various genes and involved in the regulation of diverse cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47983f8ab14d7ade121551ef32a2bcc7
https://europepmc.org/articles/PMC9253150/
https://europepmc.org/articles/PMC9253150/
Autor:
Xiaofei Lv, Bao-Dong Tang, Yu Hong, Jia-Guo Zhou, Rui-Ping Pang, Jia-wei Guo, Jin-Yan Shang, Xiao-Chun Lin, Fei-Ran Zhang, Ting-Ting Zhang, Xiu Liu, Si-Jia Liang, Qin-Yan Wu, Qian-Qian Wu, Jing-Song Ou, Jie Yu
Publikováno v:
Advanced Science, Vol 7, Iss 10, Pp n/a-n/a (2020)
Advanced Science
Advanced Science
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent form of chronic liver disease, and the mechanisms underpinning its pathogenesis have not been completely established. Transmembrane member 16A (TMEM16A), a component of the Ca2+‐activat
Autor:
Ting-Ting Zhang, Si-Jia Liang, Kai Li, Xiao-Chun Lin, Zhuo-miao Lin, Fei-Ran Zhang, Xiaofei Lv, Ying-ying Liu, Jia-wei Guo, Jia-Guo Zhou, Xiu Liu, Qian-Qian Wu, Yu Hong, Jin-Yan Shang
Publikováno v:
Acta Pharmacol Sin
Chloride (Cl(−)) homeostasis is of great significance in cardiovascular system. Serum Cl(−) level is inversely associated with the mortality of patients with heart failure. Considering the importance of angiogenesis in the progress of heart failu
Autor:
Xiao-Yun Liu, Ying-ying Liu, Xiu Liu, Ting-Ting Zhang, Xiao-Dong Fu, Xiao-Chun Lin, Jin-Yan Shang, Qingqing Lei, Fei-Ran Zhang, Si-Jia Liang, Jia-Ni Yuan, Kai Li, Jia-Guo Zhou, Xiaofei Lv
Publikováno v:
Cell Death and Disease, Vol 9, Iss 6, Pp 1-14 (2018)
Cell Death & Disease
Cell Death & Disease
The development of nephrotoxicity largely limits the clinical use of chemotherapy. MiRNAs are able to target various genes and involved in the regulation of diverse cellular processes, including cell apoptosis and death. Our study showed that miR-181
Autor:
Xiang-Yu Li, Ming-Ming Ma, Xiaofei Lv, Guan-Lei Wang, Yong-Yuan Guan, Cai-Xia Lin, Feng Yuan, Jia-Guo Zhou, Can-Zhao Liu
Publikováno v:
Circulation Journal. 82:903-913
Background TMEM16A is a critical component of Ca2+-activated chloride channels (CaCCs) and mediates basilar arterial smooth muscle cell (BASMC) proliferation in hypertensive cerebrovascular remodeling. CaMKII is a negative regulator of CaCC, and four