Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Jia‐Da Li"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Baculovirus is an obligate parasitic virus of the phylum Arthropoda. Baculovirus including Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been widely used in the laboratory and industrial preparation of proteins or protein
Externí odkaz:
https://doaj.org/article/0e4c798a5d1c489794799d851815f6ca
Autor:
Chu Jiang, Jun Guan, Xiangrong Tang, Yichun Zhang, Xiangyu Li, Yuting Li, Zhiheng Chen, Jing Zhang, Jia-Da Li
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 18 (2024)
Bisphenol A (BPA) is a widely used plasticizer known to cause various disorders. Despite a global reduction in the use of BPA-containing products, prenatal exposure to low-dose BPA, even those below established safety limits, has been linked to neuro
Externí odkaz:
https://doaj.org/article/80456cf8d2b0408d88635b872909d942
Autor:
Qing Zhang, Mengen Xing, Zhengkai Bao, Lu Xu, Yang Bai, Wanqi Chen, Wenhao Pan, Fang Cai, Qunxian Wang, Shipeng Guo, Jing Zhang, Zhe Wang, Yili Wu, Yun Zhang, Jia-Da Li, Weihong Song
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract Mutations in the Contactin-associated protein-like 2 (CNTNAP2) gene are associated with autism spectrum disorder (ASD), and ectodomain shedding of the CNTNAP2 protein plays a role in its function. However, key enzymes involved in the C-termi
Externí odkaz:
https://doaj.org/article/19850e2db8e747e9b9ff10e5865eac4d
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109974- (2024)
Summary: Prader-Willi syndrome (PWS) is a genetic disorder characterized by behavioral disturbances, hyperphagia, and intellectual disability. Several surveys indicate that PWS is also associated with cardiac abnormalities, possibly contributing to a
Externí odkaz:
https://doaj.org/article/4c8b0065676d4ef58ff23e675840eed4
Autor:
Jing Zhang, Fang Cai, Renbin Lu, Xiaoliang Xing, Lu Xu, Kunyang Wu, Zishan Gong, Qing Zhang, Yun Zhang, Mengen Xing, Weihong Song, Jia-Da Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract As the most prevalent neurodevelopmental disorders in children, autism spectrum disorders (ASD) are characterized by deficits in language development, social interaction, and repetitive behaviors or inflexible interests. Contactin associated
Externí odkaz:
https://doaj.org/article/1dad30a42e2d4d6094dffa8e3a25c313
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract FMRP, an RNA-binding protein, has previously shown to be involved in regulation of circadian rhythms in flies and mice. However, the molecular mechanism remains elusive. Here we demonstrate that core circadian component Per1 mRNA was a targe
Externí odkaz:
https://doaj.org/article/96855a94a21c4e92b9d324644ba27b94
Autor:
Dengfeng Liu, Zhengyu Xie, Panyang Gu, Xiangyu Li, Yichun Zhang, Xinying Wang, Zhiheng Chen, Suixin Deng, Yousheng Shu, Jia-Da Li
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
Attention-deficit hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder that affects approximately 5.3% of children and approximately 2.5% of adults. There is an intimate relationship between ADHD and sleep disturbance. Spec
Externí odkaz:
https://doaj.org/article/11a9b9f389444e1d96790b94fccb24b4
Autor:
Chi-Yu Li, Ting Wu, Xing-Jun Zhao, Cheng-Ping Yu, Zi-Xue Wang, Xiao-Fang Zhou, Shan-Ni Li, Jia-Da Li
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Exogenous insulin therapy is the mainstay treatment for Type-1 diabetes (T1D) caused by insulin deficiency. A fine-tuned insulin supply system is important to maintain the glucose homeostasis. In this study, we present a designed cell system that pro
Externí odkaz:
https://doaj.org/article/e662e5e7abab44f89d5189bbff77ed8f
Autor:
Huadie Liu, Ye Liu, Seung-Gi Jin, Jennifer Johnson, Hongwen Xuan, Di Lu, Jianshuang Li, Lukai Zhai, Xianfeng Li, Yaguang Zhao, Minmin Liu, Sonya E.L. Craig, Joseph S. Floramo, Vladimir Molchanov, Jie Li, Jia-Da Li, Connie Krawczyk, Xiaobing Shi, Gerd P. Pfeifer, Tao Yang
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112012- (2023)
Summary: Long bones are generated by mesoderm-derived skeletal progenitor/stem cells (SSCs) through endochondral ossification, a process of sequential chondrogenic and osteogenic differentiation tightly controlled by the synergy between intrinsic and
Externí odkaz:
https://doaj.org/article/48f22ec1bcce41a7b2d544163726c5c6
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Knowledge of mandibular growth and development is essential for diagnosis of malformation and early interception. A previous method of quantifying mandibular growth using the distances between selected anatomical landmarks over the growth period does
Externí odkaz:
https://doaj.org/article/cb804a8a7cfb4bcb819947e5f6fb3f74