Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Ji-dong Fu"'
Autor:
Kenneth R. Laurita, Shenaz Khan, Tracy McMahon, Adrienne T. Dennis, Vincent Li, Robert Gaivin, Hima Sapa, Ji-dong Fu, Jeffrey R. Schelling
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Chronic kidney disease (CKD) affects more than 20 million people in the US, and it is associated with a significantly increased risk of sudden cardiac death (SCD). Despite the significance, the mechanistic relationship between SCD and CKD is
Externí odkaz:
https://doaj.org/article/928179ec18204ab3a05319cdaade74b5
Autor:
Yang Zheng, Xiaoping Wan, Dandan Yang, Angelina Ramirez-Navarro, Haiyan Liu, Ji-Dong Fu, Isabelle Deschênes
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Nav1.5, encoded by the gene SCN5A, is the predominant voltage-gated sodium channel expressed in the heart. It initiates the cardiac action potential and thus is crucial for normal heart rhythm and function. Dysfunctions in Nav1.5 have been involved i
Externí odkaz:
https://doaj.org/article/6c486a91cdbd402ea3d8c7514304b5fd
Autor:
Emre Bektik, Yu Sun, Adrienne T. Dennis, Phraew Sakon, Dandan Yang, Isabelle Deschênes, Ji-Dong Fu
Publikováno v:
Cells, Vol 10, Iss 7, p 1572 (2021)
Direct cardiac reprogramming of fibroblasts into induced cardiomyocytes (iCMs) is a promising approach but remains a challenge in heart regeneration. Efforts have focused on improving the efficiency by understanding fundamental mechanisms. One major
Externí odkaz:
https://doaj.org/article/4e5d54f129724173b8d171571811c858
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183000 (2017)
The direct reprogramming of cardiac fibroblasts into induced cardiomyocyte (CM)-like cells (iCMs) holds great promise in restoring heart function. We previously found that human fibroblasts could be reprogrammed toward CM-like cells by 7 reprogrammin
Externí odkaz:
https://doaj.org/article/c3b65f63afd14da6b842eb9480ac2bfd
Autor:
Emre Bektik, Ji-dong Fu
Publikováno v:
Cells, Vol 8, Iss 7, p 679 (2019)
Coronary artery disease is the most common form of cardiovascular diseases, resulting in the loss of cardiomyocytes (CM) at the site of ischemic injury. To compensate for the loss of CMs, cardiac fibroblasts quickly respond to injury and initiate car
Externí odkaz:
https://doaj.org/article/89787e840ed6432b93bac0a753ad3420
Autor:
Ji-Dong Fu, Stephanie N Rushing, Deborah K Lieu, Camie W Chan, Chi-Wing Kong, Lin Geng, Kitchener D Wilson, Nipavan Chiamvimonvat, Kenneth R Boheler, Joseph C Wu, Gordon Keller, Roger J Hajjar, Ronald A Li
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27417 (2011)
MicroRNAs (miRs) negatively regulate transcription and are important determinants of normal heart development and heart failure pathogenesis. Despite the significant knowledge gained in mouse studies, their functional roles in human (h) heart remain
Externí odkaz:
https://doaj.org/article/c906e6f1799b400b8bf5c02dcd4e7ff2
Autor:
Feng Cao, Roger A Wagner, Kitchener D Wilson, Xiaoyan Xie, Ji-Dong Fu, Micha Drukker, Andrew Lee, Ronald A Li, Sanjiv S Gambhir, Irving L Weissman, Robert C Robbins, Joseph C Wu
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3474 (2008)
Human embryonic stem cells (hESCs) can serve as a potentially limitless source of cells that may enable regeneration of diseased tissue and organs. Here we investigate the use of human embryonic stem cell-derived cardiomyocytes (hESC-CMs) in promotin
Externí odkaz:
https://doaj.org/article/81413be0fedb48538ec97cca608f5bd7
Autor:
Kacira, Ege, Pittman, Mitchell, Yang, Dandan, Sturgill, Sarah L., Ziolo, Mark T., Yuchi Han, Deschênes, Isabelle, Ji-dong Fu
Publikováno v:
Circulation: Heart Failure; Jan2024, Vol. 17 Issue 1, p62-65, 4p
Autor:
Dandan Yang, Xiaoping Wan, Schwieterman, Neill, Cavus, Omer, Kacira, Ege, Xianyao Xu, Laurita, Kenneth R., Wold, Loren E., Hund, Thomas J., Mohler, Peter J., Deschênes, Isabelle, Ji-Dong Fu
Publikováno v:
Circulation: Arrhythmia & Electrophysiology; Jan2024, Vol. 17 Issue 1, p34-48, 15p
Autor:
Yuliang Feng, Liuyang Cai, Wanzi Hong, Chunxiang Zhang, Ning Tan, Mingyang Wang, Cheng Wang, Feng Liu, Xiaohong Wang, Jianyong Ma, Chen Gao, Mohit Kumar, Yuanxi Mo, Qingshan Geng, Changjun Luo, Yan Lin, Haiyang Chen, Shuang-Yin Wang, Michael J. Watson, Anil G. Jegga, Roger A. Pedersen, Ji-dong Fu, Zhao V. Wang, Guo-Chang Fan, Sakthivel Sadayappan, Yigang Wang, Siim Pauklin, Feng Huang, Wei Huang, Lei Jiang
Publikováno v:
Circulation
Background: Transcriptional reconfiguration is central to heart failure, the most common cause of which is dilated cardiomyopathy (DCM). The effect of 3-dimensional chromatin topology on transcriptional dysregulation and pathogenesis in human DCM rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dd87ce7e8e59aa8b3862782535c15d
https://doi.org/10.1161/circulationaha.121.055781
https://doi.org/10.1161/circulationaha.121.055781