Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ji-Yeong Byeon"'
Autor:
Se-Hyung Kim, Ji-Yeong Byeon, Choong-Min Lee, Seok-Yong Lee, Yun Jeong Lee, Choon-Gon Jang, Eui Hyun Jung
Publikováno v:
Archives of Pharmacal Research. 42:1101-1106
Zolpidem is extensively metabolized by CYP3A4, CYP2C9 and CYP1A2. Previous studies demonstrated that pharmacokinetics of zolpidem was affected by CYP inhibitors, but not by short-term treatment of clarithromycin. The objective of this study was to in
Autor:
Choon-Gon Jang, Se-Hyung Kim, Eui-Hyun Jung, Ji-Yeong Byeon, Yun Jeong Lee, Choong-Min Lee, Young-Hoon Kim, Seok-Yong Lee, Won-Ki Chae
Publikováno v:
Archives of Pharmacal Research. 41:861-866
Zolpidem is indicated for the short-term treatment of insomnia and it is predominantly metabolized by CYP3A4, and to a lesser extent by CYP2C19, CYP1A2, and CYP2C9. Therefore, we evaluated the effects of CYP2C19 genetic polymorphisms on the pharmacok
Autor:
Choon-Gon Jang, Chang-Ik Choi, Jung-Woo Bae, Yun Jeong Lee, Ji-Yeong Byeon, Se-Hyung Kim, Young-Hoon Kim, Choong-Min Lee, Seok-Yong Lee
Publikováno v:
Archives of Pharmacal Research. 41:564-570
Tamsulosin, a selective antagonist of the α1-adrenoceptor, is primarily metabolized by CYP3A4 and CYP2D6, and tamsulosin exposure is significantly increased according to the genetic polymorphism of CYP2D6. In this study, we investigated the effects
Autor:
Won Ki Chae, Choong-Min Lee, Ji-Yeong Byeon, Seok-Yong Lee, Chang-Ik Choi, Choon-Gon Jang, Yun Jeong Lee, Young-Hoon Kim, Se-Hyung Kim, Mi-Jung Kim, Eui Hyun Jung
Publikováno v:
Archives of Pharmacal Research. 41:347-353
Clomiphene citrate, a selective estrogen receptor modulator, is metabolized into its 4-hydroxylated active metabolites, primarily by CYP2D6. In this study, we investigated the effects of the most common CYP2D6 variant allele in Asians, CYP2D6*10, on
Autor:
Ji-Yeong Byeon, Chang-Ik Choi, Choon-Gon Jang, Yun Jeong Lee, Se-Hyung Kim, Young-Hoon Kim, Jung-Woo Bae, Choong-Min Lee, Seok-Yong Lee
Publikováno v:
Archives of Pharmacal Research. 40:1455-1463
Tolterodine, a nonselective muscarinic antagonist available only as immediate release (IR) or extended release (ER) oral formulations, is used for the treatment of overactive bladder (OAB). This study aimed to compare the efficacy and extent of dry m
Autor:
Ji-Yeong Byeon, Choong-Min Lee, Seok-Yong Lee, Yun Jeong Lee, Se-Hyung Kim, Young-Hoon Kim, Won Ki Chae, Choon-Gon Jang, Eui Hyun Jung
Publikováno v:
Archives of Pharmacal Research. 40:1287-1295
Tolterodine is a nonselective muscarinic antagonist that is indicated for the overactive urinary bladder and other urinary difficulties. We developed and validated a simple, rapid and sensitive high-performance liquid chromatography analytical method
Autor:
Choong-Min Lee, Seok-Yong Lee, Ji-Yeong Byeon, Choon-Gon Jang, Chang-Keun Cho, Eui Hyun Jung, Kyung-Yul Oh, Hyo-Bin Shin, Chang Woo Lim, Yun Jeong Lee
Publikováno v:
Archives of Pharmacal Research. 44:323-323
Autor:
Donghyun Kim, Yun Jeong Lee, Young-Hoon Kim, Sang Sup Whang, Ji-Yeong Byeon, H.Y. Lim, Do-Hoon Kim, Choong-Min Lee, Seok-Yong Lee, Se-Hyung Kim, Jung-Woo Bae, Chang-Ik Choi, Choon-Gon Jang
Publikováno v:
Archives of Pharmacal Research. 40:382-390
Celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, is used for the treatment of rheumatoid arthritis and osteoarthritis. The predominant hepatic metabolism of celecoxib to celecoxib carboxylic acid (CCA) is mediated mainly by CYP2C9. We investi
Autor:
Se-Hyung Kim, Ji-Yeong Byeon, Won Ki Chae, Seok-Yong Lee, Choon-Gon Jang, Eui Hyun Jung, Young-Hoon Kim, Choong-Min Lee, Yun Jeong Lee, Yea-Jin Lee
Publikováno v:
Archives of pharmacal research. 42(2)
Tolterodine is metabolized to an active 5-hydroxymethyl tolterodine (5-HMT) by CYP2D6. This study investigated the relationship between CYP2D6 genotypes and pharmacokinetics of tolterodine and its active metabolite in healthy Korean subjects. All vol
Autor:
Choon-Gon Jang, Eui-Hyun Jung, Ji-Yeong Byeon, Choong-Min Lee, Se-Hyung Kim, Yun Jeong Lee, Young-Hoon Kim, Won-Ki Chae, Seok-Yong Lee
Publikováno v:
Archives of pharmacal research. 41(9)
Zolpidem is predominantly metabolized by CYP3A4, and to a lesser extent by CYP2C9, CYP1A2, CYP2D6 and CYP2C19. The aim of this study was to identify the effects of CYP2C9*3 allele on the pharmacokinetics of zolpidem. Healthy male subjects were divide