Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Ji-Xin Tang"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Cancer is the main cause of death in the world. There are several therapies that are in practice for cancer cure including radiotherapy, chemotherapy, and surgery. Among the chemotherapies, natural products are considered comparable safe, easily avai
Externí odkaz:
https://doaj.org/article/99c2a0afb234420dba5b7a85ead49c46
Autor:
Dan Wu, Li-Feng Huang, Xiao-Cui Chen, Xiao-Rong Huang, Hui-Yuan Li, Ning AN, Ji-Xin Tang, Hua-Feng Liu, Chen Yang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-12 (2023)
Abstract The endoplasmic reticulum (ER) plays important roles in biosynthetic and metabolic processes, including protein and lipid synthesis, Ca2+ homeostasis regulation, and subcellular organelle crosstalk. Dysregulation of ER homeostasis can cause
Externí odkaz:
https://doaj.org/article/22c71485a479425b8ba93b68f622324c
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Diabetic kidney disease (DKD) is a chronic inflammatory condition that affects approximately 20-40% of individuals with diabetes. Sodium-glucose co-transporter 2 (SGLT-2) inhibitors, emerging as novel hypoglycemic agents, have demonstrated significan
Externí odkaz:
https://doaj.org/article/fbc4d380ab5241eaaa792bdcacfdf073
Autor:
Xiao-cui Chen, Li-feng Huang, Ji-xin Tang, Dan Wu, Ning An, Zhen-nan Ye, Hui-yao Lan, Hua-feng Liu, Chen Yang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115122- (2023)
Nephrotoxicity is a major side effect of cisplatin treatment of solid tumors in the clinical setting. Long-term low-dose cisplatin administration causes renal fibrosis and inflammation. However, few specific medicines with clinical application value
Externí odkaz:
https://doaj.org/article/c444ad991df14e4d8f1f7e8c2bdbc4fd
Autor:
Ji-Xin Tang, Fu-Hui Xiao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/ceba72fb1f7e44e99b4884709d1f425a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13558 (2023)
Inflammation is a crucial pathological feature in cancers and kidney diseases, playing a significant role in disease progression. Cyclin-dependent kinases CDK4 and CDK6 not only contribute to cell cycle progression but also participate in cell metabo
Externí odkaz:
https://doaj.org/article/8601a13b194d47c498947b5d373fa5bf
Autor:
Hui-Yuan Li, Li-Feng Huang, Xiao-Rong Huang, Dan Wu, Xiao-Cui Chen, Ji-Xin Tang, Ning An, Hua-Feng Liu, Chen Yang
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Approximately one-third to two-thirds of the patients with SLE progress to lupus nephritis (LN). The pathogenesis of SLE and LN has not yet been fully elucidated, and effective treat
Externí odkaz:
https://doaj.org/article/43d107ac5eb94339bc2096cc07c27d23
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As the essential regulators of organ fibrosis, macrophages undergo marked phenotypic and functional changes after organ injury. These changes in macrophage phenotype and function can result in maladaptive repair, causing chronic inflammation and the
Externí odkaz:
https://doaj.org/article/3e4afa61ccca41a1b0aabfebb9be06d6
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/5cb72c93526d4728886b94f49f1012eb
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8593 (2023)
The accumulation of protein aggregates is the hallmark of many neurodegenerative diseases. The dysregulation of protein homeostasis (or proteostasis) caused by acute proteotoxic stresses or chronic expression of mutant proteins can lead to protein ag
Externí odkaz:
https://doaj.org/article/11a72eb2cabb49389b77a3c7b15a91d4