Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ji-Rui Yang"'
Autor:
Akshay Ravish, Rashmi Shivakumar, Zhang Xi, Min Hee Yang, Ji-Rui Yang, Ananda Swamynayaka, Omantheswara Nagaraja, Mahendra Madegowda, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Vijay Pandey, Gautam Sethi, Kwang Seok Ahn, Peter E. Lobie, Basappa Basappa
Publikováno v:
Bioengineering, Vol 10, Iss 2, p 159 (2023)
In breast cancer (BC), STAT3 is hyperactivated. This study explored the design of imidazopyridine-tethered pyrazolines as a de novo drug strategy for inhibiting STAT3 phosphorylation in human BC cells. This involved the synthesis and characterization
Externí odkaz:
https://doaj.org/article/3a341afcd4c54165a48f27aa213db955
Autor:
Basappa Basappa, Lisha K. Poonacha, Zhang Xi, Divakar Vishwanath, Ji-Rui Yang, Omantheswara Nagaraja, Ananda Swamynayaka, Mahendra Madegowda, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Doddahosuru Mahadevappa Gurudatt, Vijay Pandey, Nanjundaswamy Shivananju, Kwang Seok Ahn, Gautam Sethi, Peter E. Lobie, Priya Babu Shubha
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 172 (2023)
Small molecules are being used to inhibit cyclin dependent kinase (CDK) enzymes in cancer treatment. There is evidence that CDK is a drug-target for cancer therapy across many tumor types because it catalyzes the transfer of the terminal phosphate of
Externí odkaz:
https://doaj.org/article/6255aa71414e4e5cbb51b945dfc1b2dd
Autor:
Suresha N. Deveshegowda, Prashant K. Metri, Rashmi Shivakumar, Ji-Rui Yang, Shobith Rangappa, Ananda Swamynayaka, Muthu K. Shanmugam, Omantheswara Nagaraja, Mahendra Madegowda, Priya Babu Shubha, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Vijay Pandey, Kwang Seok Ahn, Peter E. Lobie, Basappa Basappa
Publikováno v:
Molecules, Vol 27, Iss 9, p 2848 (2022)
A number of uracil amides cleave poly (ADP-ribose) polymerase and therefore novel thiouracil amide compounds were synthesized and screened for the loss of cell viability in a human-estrogen-receptor-positive breast cancer cell line. The synthesized c
Externí odkaz:
https://doaj.org/article/835b5bddc7f74e5c85ff91e48605dc4b
Autor:
Divakar Vishwanath, Swamy S. Girimanchanaika, Dukanya Dukanya, Shobith Rangappa, Ji-Rui Yang, Vijay Pandey, Peter E. Lobie, Basappa Basappa
Publikováno v:
Molecules, Vol 27, Iss 3, p 703 (2022)
Novel PARP inhibitors with selective mode-of-action have been approved for clinical use. Herein, oxadiazole based ligands that are predicted to target PARP-1 have been synthesized and screened for the loss of cell viability in mammary carcinoma cells
Externí odkaz:
https://doaj.org/article/46251b2a8bd946a9937f09d7b6efec2a
Publikováno v:
Journal of Functional Foods, Vol 1, Iss 2, Pp 145-152 (2009)
Momordica grosvenori Swingle, a traditional medicinal herb, is known to possess anti-inflammatory anti-oxidative, anti-diabetic, and nephroprotective activities. Here, we investigated the inhibitory effects of M. grosvenori Swingle extract (MSE) on t
Externí odkaz:
https://doaj.org/article/d180fc1e820d4f83a5c5e487466bbc20
Autor:
Ji-Rui Yang, 楊季叡
96
Part I: Momordica grosvenori Swingle tastes sweet and lean to cold in medical speciatity. It is good at stopping couching, dissolving phlegm, purifying the lung, smoothing the intestines, lowering blood sugar, combating inflammation and curin
Part I: Momordica grosvenori Swingle tastes sweet and lean to cold in medical speciatity. It is good at stopping couching, dissolving phlegm, purifying the lung, smoothing the intestines, lowering blood sugar, combating inflammation and curin
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/10917144423362210656
Autor:
Suresha N. Deveshegowda, Ji-Rui Yang, Zhang Xi, Omantheswara Nagaraja, Kashifa Fazl-Ur-Rahman, Bhanuprakash C. Narasimhachar, Gautam Sethi, Ganga Periyasamy, Mahendra Madegowda, Shobith Rangappa, Vijay Pandey, Peter E. Lobie, Basappa Basappa
Publikováno v:
Catalysts
Volume 13
Issue 2
Pages: 228
Volume 13
Issue 2
Pages: 228
Bioactive dihydropyrimidinones (DHPs) were designed and synthesized by a multicomponent Biginelli reaction. The reaction was catalyzed by the polarized surface of nano-zirconium dioxide with partial positive charge of 0.52e at the Zr center and a neg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9223d4e9db0b3921351724adf79bf2
https://doi.org/10.3390/catal13020228
https://doi.org/10.3390/catal13020228
Autor:
Divakar Vishwanath, Swamy S. Girimanchanaika, Dukanya Dukanya, Shobith Rangappa, Ji-Rui Yang, Vijay Pandey, Peter E. Lobie, Basappa Basappa
Publikováno v:
Molecules; Volume 27; Issue 3; Pages: 703
Molecules, Vol 27, Iss 703, p 703 (2022)
Molecules, Vol 27, Iss 703, p 703 (2022)
Novel PARP inhibitors with selective mode-of-action have been approved for clinical use. Herein, oxadiazole based ligands that are predicted to target PARP-1 have been synthesized and screened for the loss of cell viability in mammary carcinoma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472bcf8cb48576d8ef060b7398ee8761
https://pubmed.ncbi.nlm.nih.gov/35163965
https://pubmed.ncbi.nlm.nih.gov/35163965
Autor:
Yi Zuo, Chao-zheng Zhang, Qing Ren, Yao Chen, Xiao Li, Ji-rui Yang, Hong-xiang Li, Wen-tao Tang, Hing-Man HO, Chen Sun, Mei-mei Li, Bo Ren, Yun Deng, Mao-lin Wang, Jun Lu
Publikováno v:
Phytomedicine. 99:154015
Breast cancer is one of the malignant tumors with the highest morbidity and mortality rate. Numerous efficient anti-breast cancer drugs are being derived from the development of natural products. Voacamine (VOA), a bisindole alkaloid isolated from Vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b33d03f9fc74a2ac1f60e2fb4deffc
https://doi.org/10.1016/j.phymed.2022.154015
https://doi.org/10.1016/j.phymed.2022.154015
Autor:
Ya Ping Chen, Ji Rui Yang, Hsiu Jung Lo, Pin Feng Hung, Wen Chan Yang, Kai Cheng Hsu, Ching Yu Yen, Ko Jiunn Liu, Chia Huei Lee, Tsorng Harn Fong, Hsuan Lien Chung
Publikováno v:
Cancers
Volume 12
Issue 11
Cancers, Vol 12, Iss 3148, p 3148 (2020)
Volume 12
Issue 11
Cancers, Vol 12, Iss 3148, p 3148 (2020)
Poor oral hygiene (POH) is associated with oral squamous cell carcinoma (OSCC). Oral microbes often proliferate due to POH. Array data show that LDOC1 plays a role in immunity against pathogens. We investigated whether LDOC1 regulates the production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87aaa04bf635ef15be02768dbd41469b