Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ji-Lei Jiang"'
Autor:
Hongmei Zhao, Jozsef Karman, Ji-Lei Jiang, Jinhua Zhang, Nathan Gumlaw, John Lydon, Qun Zhou, Huawei Qiu, Canwen Jiang, Seng H Cheng, Yunxiang Zhu
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63530 (2013)
Crosslinking ligand-engaged cytotoxic T lymphocyte antigen-4 (CTLA-4) to the T cell receptor (TCR) with a bispecific fusion protein (BsB) comprised of a mutant mouse CD80 and lymphocyte activation antigen-3 (LAG-3) has been shown to attenuate TCR sig
Externí odkaz:
https://doaj.org/article/4bc2461a64c84f2eb8cb8f2124dc291e
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34684 (2012)
Pre-existing immunity against adeno-associated virus (AAV) remains a major challenge facing the clinical use of systemic administration of recombinant AAV vectors for the treatment of genetic and acquired diseases using gene therapy. In this study, w
Externí odkaz:
https://doaj.org/article/bb51397e77484489b63e61ad2e2ef4e3
Autor:
Nathan Gumlaw, Jose Sancho, Yunxiang Zhu, Canwen Jiang, Ji-Lei Jiang, Juanita Campos-Rivera, Hongmei Zhao, Seng H. Cheng, Jozsef Karman, Jinhua Zhang
Publikováno v:
Journal of Biological Chemistry. 287:11098-11107
Cross-linking of ligand-engaged cytotoxic T lymphocyte antigen-4 (CTLA-4) to the T cell receptor (TCR) during the early phase of T cell activation attenuates TCR signaling, leading to T cell inhibition. To promote this event, a bispecific fusion prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833fc6b60b266bf888411842b03f2742
https://doi.org/10.1074/jbc.m111.283705
https://doi.org/10.1074/jbc.m111.283705
Autor:
Antoinette M. Zuliani, Michael W. Heartlein, Victoria A. Roman, Richard F. Selden, Douglas A. Treco, Ji-Lei Jiang, Joan W. Sellers
Publikováno v:
Proceedings of the National Academy of Sciences. 91:10967-10971
The application of somatic cell gene therapy to large patient populations will require the development of safe and practical approaches to the generation and characterization of genetically manipulated cells. Transkaryotic implantation is a gene ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e912d8c77ae0589e2fd71df3b14727b9
https://doi.org/10.1073/pnas.91.23.10967
https://doi.org/10.1073/pnas.91.23.10967
Autor:
Johanne Kaplan, Craig Siegel, Seng H. Cheng, Pete Maniatis, Wei-Lien Chuang, Nathan Gumlaw, Yunxiang Zhu, Canwen Jiang, Hongmei Zhao, Ji Lei Jiang, James A. Shayman, Jozsef Karman, Jinhua Zhang, Andrea Edling
Lipid rafts reportedly have a role in coalescing key signaling molecules into the immunological synapse during T cell activation, thereby modulating T cell receptor (TCR) signaling activity. Recent findings suggest that a correlation may exist betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f860e80008486541fafd33304aed3bd2
https://europepmc.org/articles/PMC3083190/
https://europepmc.org/articles/PMC3083190/
Autor:
Scott D. Bercury, Robin J. Ziegler, Mariko Kudo, Robert J. Mattaliano, Canwen Jiang, Seng H. Cheng, Jinhua Zhang, Ji-Lei Jiang, Nathan Gumlaw, William M. Canfield, Karen Lee, Yunxiang Zhu, Tim Edmunds
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 17(6)
Improving the delivery of therapeutics to disease-affected tissues can increase their efficacy and safety. Here, we show that chemical conjugation of a synthetic oligosaccharide harboring mannose 6-phosphate (M6P) residues onto recombinant human acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d467d2053b2922c9dc1b5110db09615e
https://pubmed.ncbi.nlm.nih.gov/19277015
https://pubmed.ncbi.nlm.nih.gov/19277015
Autor:
Yunxiang Zhu, Jozsef Karman, Ji-Lei Jiang, Nathan Gumlaw, Hongmei Zhao, Juanita Campos-Rivera, Jose Sancho, Jinhua Zhang, Canwen Jiang, Seng H. Cheng
Publikováno v:
The Journal of Immunology. 188:72.2-72.2
ABSTRACT Crosslinking of ligand-engaged cytotoxic T lymphocyte antigen-4 (CTLA-4) to the T cell receptor (TCR) during the early phase of T cell activation attenuates TCR signaling, leading to T cell inhibition. To promote this event, a bispecific fus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44548eb65df786782c92c7de44b566e
https://doi.org/10.4049/jimmunol.188.supp.72.2
https://doi.org/10.4049/jimmunol.188.supp.72.2
Publikováno v:
PLoS ONE; Apr2012, Vol. 7 Issue 4, p1-9, 9p
Autor:
Karman, Jozsef1, Ji-Lei Jiang1, Gumlaw, Nathan1, Hongmei Zhao1, Campos-Rivera, Juanita1, Sancho, Jose1, Jinhua Zhang1, Canwen Jiang1, Cheng, Seng H.1, Yunxiang Zhu1 yunxiang.zhu@genzyme.com.
Publikováno v:
Journal of Biological Chemistry. 3/30/2012, Vol. 287 Issue 14, p11098-11107. 10p.
Autor:
Yunxiang Zhu1 yunxiang.zhu@genzyme.com, Ji-Lei Jiang1, Gumlaw, Nathan K.1, Jinhua Zhang1, Bercury, Scott D.1, Ziegler, Robin J.1, Lee, Karen1, Kudo, Mariko1, Canfield, William M.1, Edmunds, Timothy1, Jiang, Canwen1, Mattaliano, Robert J.1, Cheng, Seng H.1 seng.cheng@genzyme.com
Publikováno v:
Molecular Therapy. Jun2009, Vol. 17 Issue 6, p954-963. 10p. 1 Color Photograph, 5 Graphs.