Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Ji-Gang Zhang"'
Autor:
Gregory R. Keele, Ji-Gang Zhang, John Szpyt, Ron Korstanje, Steven P. Gygi, Gary A. Churchill, Devin K. Schweppe
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112715- (2023)
Summary: Maintenance of protein homeostasis degrades with age, contributing to aging-related decline and disease. Previous studies have primarily surveyed transcriptional aging changes. To define the effects of age directly at the protein level, we p
Externí odkaz:
https://doaj.org/article/0ebf66b87b984c858446f29df12b141a
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-17 (2021)
Abstract Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that contribute to tumor progression and therapy resistance. However, the underlying processes are still unclear. Elucidation of the key hallmarks and resist
Externí odkaz:
https://doaj.org/article/572359b289f14fb4884518f65e272f0a
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 36, Iss 4, Pp 250-256 (2020)
Abstract MicroRNA‐425‐5p (miR‐425‐5p) has been reported to be involved in the tumorigenesis of several tumors, but its function in breast cancer is still unknown. In this study, miR‐425‐5p was found significantly upregulated in breast can
Externí odkaz:
https://doaj.org/article/791ac556321744e5b7199d147a547aa3
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Vasculogenic mimicry (VM), defined as a capability of aggressive tumor Cells to mimic embryonic vasculogenic networks, caused poor prognosis in hepatocellular carcinoma (HCC). Rho kinases (ROCK), p21-activated kinase (PAK), hypoxi
Externí odkaz:
https://doaj.org/article/830df4a7b7664828956b4ab22e0f1f14
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Recently, N6-methyl-adenosine (m6A) ribonucleic acid (RNA) modification, a critical and common internal RNA modification in higher eukaryotes, has generated considerable research interests. Extensive studies have revealed that non-coding RNA m6A modi
Externí odkaz:
https://doaj.org/article/dcbf94c891594d58ad50eaf40d3b2397
Autor:
Feng-Qi Tan, Chun-Miao Ma, Xu-Yang Zhang, Ji-Gang Zhang, Long Tan, Dan-Dan Zhao, Xian-Kun Li, Yu-Qian Jing
Publikováno v:
Energies, Vol 15, Iss 19, p 7359 (2022)
The low-permeability conglomerate reservoir in the Mahu Sag has great resource potential, but its strong heterogeneity and complex microscopic pore structure lead to a high oil-gas decline ratio and low recovery ratio. Clarifying the migration rule o
Externí odkaz:
https://doaj.org/article/6271f5bdb050448c86093966075ae8ec
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Our previous study described the crucial role of Rho-associated coiled-coil containing-kinases (ROCK) in hepatocellular carcinoma (HCC). However, the potential significance of long noncoding RNA downstream of ROCK is largely unkno
Externí odkaz:
https://doaj.org/article/497bae8f2090455f8e2260c90b822299
Autor:
Amy R. Dunn, Niran Hadad, Sarah M. Neuner, Ji-Gang Zhang, Vivek M. Philip, Logan Dumitrescu, Timothy J. Hohman, Jeremy H. Herskowitz, Kristen M. S. O’Connell, Catherine C. Kaczorowski
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Developing strategies to maintain cognitive health is critical to quality of life during aging. The basis of healthy cognitive aging is poorly understood; thus, it is difficult to predict who will have normal cognition later in life. Individuals may
Externí odkaz:
https://doaj.org/article/55c45b3c6f334db690a33914c1daf442
Autor:
Qi Zhao, Hui Shen, Kuan-Jui Su, Ji-Gang Zhang, Qing Tian, Lan-Juan Zhao, Chuan Qiu, Qiang Zhang, Timothy J. Garrett, Jiawang Liu, Hong-Wen Deng
Publikováno v:
Nutrition & Metabolism, Vol 15, Iss 1, Pp 1-9 (2018)
Abstract Background Individuals’ peak bone mineral density (BMD) achieved and maintained at ages 20–40 years is the most powerful predictor of low bone mass and osteoporotic fractures later in life. The aim of this study was to identify metabolom
Externí odkaz:
https://doaj.org/article/856a55c0ad09412f88ed5d5d012c3ce9
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2271-2279 (2017)
Integrating diverse genomics data can provide a global view of the complex biological processes related to the human complex diseases. Although substantial efforts have been made to integrate different omics data, there are at least three challenges
Externí odkaz:
https://doaj.org/article/ee2a92544d00464b9cea36b72d99df9a