Zobrazeno 1 - 10
of 220
pro vyhledávání: '"Ji-Fan Hu"'
Autor:
Wenjun Wang, Lei Zhou, Hui Li, Tingge Sun, Xue Wen, Wei Li, Miguel A. Esteban, Andrew R. Hoffman, Ji-Fan Hu, Jiuwei Cui
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-14 (2024)
Abstract The N6-methyladenosine (m6A) RNA modification plays essential roles in multiple biological processes, including stem cell fate determination. To explore the role of the m6A modification in pluripotent reprogramming, we used RNA-seq to map m6
Externí odkaz:
https://doaj.org/article/0538708e10884724abb35f2ecfeb727e
Autor:
Lei Zhou, Hui Li, Tingge Sun, Xue Wen, Chao Niu, Min Li, Wei Li, Miguel A. Esteban, Andrew R. Hoffman, Ji-Fan Hu, Jiuwei Cui
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract Pluripotent stem cells (PSCs) provide unlimited resources for regenerative medicine because of their potential for self-renewal and differentiation into many different cell types. The pluripotency of these PSCs is dynamically regulated at mu
Externí odkaz:
https://doaj.org/article/725dfdc435844e6aa14b3ebf127107db
Autor:
Shanshan Liu, Benzheng Jiao, Hongguang Zhao, Xinyue Liang, Fengyan Jin, Xiaodong Liu, Ji‐Fan Hu
Publikováno v:
Advanced Science, Vol 11, Iss 1, Pp n/a-n/a (2024)
Abstract As one of novel hallmarks of cancer, lipid metabolic reprogramming has recently been becoming fascinating and widely studied. Lipid metabolic reprogramming in cancer is shown to support carcinogenesis, progression, distal metastasis, and che
Externí odkaz:
https://doaj.org/article/9e3008dc9333482692fd6d9ff0c964a0
Autor:
Chao Niu, Min Li, Yongchong Chen, Xiaoying Zhang, Shan Zhu, Xin Zhou, Lei Zhou, Zhaozhi Li, Jianting Xu, Ji-fan Hu, Yufeng Wang, Jiuwei Cui
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells perform immune surveillance functions in tumors. The antitumor effects of NK cells are closely related to tumor occurrence and development. However, the molecular factors that determine NK cell antitumor activity remain to b
Externí odkaz:
https://doaj.org/article/fd7fe5254cb1425fb80c02a9ede53a7b
Autor:
Zhonghua Du, Xue Wen, Yichen Wang, Lin Jia, Shilin Zhang, Yudi Liu, Lei Zhou, Hui Li, Wang Yang, Cong Wang, Jingcheng Chen, Yajing Hao, Huiling Chen, Dan Li, Naifei Chen, Ilkay Celik, Yanbo Zhu, Zi Yan, Changhao Fu, Shanshan Liu, Benzheng Jiao, Zhuo Wang, Hui Zhang, Günhan Gülsoy, Jianjun Luo, Baoming Qin, Sujun Gao, Philipp Kapranov, Miguel A. Esteban, Songling Zhang, Wei Li, Ferhat Ay, Runsheng Chen, Andrew R. Hoffman, Jiuwei Cui, Ji-Fan Hu
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-29 (2021)
Abstract Background A specific 3-dimensional intrachromosomal architecture of core stem cell factor genes is required to reprogram a somatic cell into pluripotency. As little is known about the epigenetic readers that orchestrate this architectural r
Externí odkaz:
https://doaj.org/article/2ce0442b8dc449168fea014f3b305641
Autor:
Yijing Zhao, Lei Zhou, Hui Li, Tingge Sun, Xue Wen, Xueli Li, Ying Meng, Yan Li, Mengmeng Liu, Shanshan Liu, Su-Jeong Kim, Jialin Xiao, Lingyu Li, Songling Zhang, Wei Li, Pinchas Cohen, Andrew R. Hoffman, Ji-Fan Hu, Jiuwei Cui
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 264-276 (2021)
Mitochondrial dysfunction is a metabolic hallmark of cancer cells. In search of molecular factors involved in this dysregulation in hepatocellular carcinoma (HCC), we found that the nuclear-encoded long noncoding RNA (lncRNA) MALAT1 (metastasis-assoc
Externí odkaz:
https://doaj.org/article/c861857d405a49bba84dca50e249ee81
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mitophagy is a specialized autophagic pathway responsible for the selective removal of damaged or dysfunctional mitochondria by targeting them to the autophagosome in order to maintain mitochondria quality. The role of mitophagy in tumorigenesis has
Externí odkaz:
https://doaj.org/article/e57cc05fe8664936930a21a46de261f5
Autor:
Xue Wen, Qi Zhang, Lei Zhou, Zhaozhi Li, Xue Wei, Wang Yang, Jiaomei Zhang, Hui Li, Zijun Xu, Xueling Cui, Songling Zhang, Yufeng Wang, Wei Li, Andrew R. Hoffman, Zhonghui Liu, Ji-Fan Hu, Jiuwei Cui
Publikováno v:
Cells, Vol 11, Iss 19, p 3130 (2022)
Recurrent spontaneous abortion (RSA) is a highly heterogeneous complication of pregnancy with the underlying mechanisms remaining uncharacterized. Dysregulated decidualization is a critical contributor to the phenotypic alterations related to pregnan
Externí odkaz:
https://doaj.org/article/c838db9374cd4a0e833a316aa6457a9e
Autor:
Naifei Chen, Gang Zhao, Xu Yan, Zheng Lv, Hongmei Yin, Shilin Zhang, Wei Song, Xueli Li, Lingyu Li, Zhonghua Du, Lin Jia, Lei Zhou, Wei Li, Andrew R. Hoffman, Ji-Fan Hu, Jiuwei Cui
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Friend leukemia virus integration 1 (FLI1), an ETS transcription factor family member, acts as an oncogenic driver in hematological malignancies and promotes tumor growth in solid tumors. However, little is known about the mechani
Externí odkaz:
https://doaj.org/article/d55e6b9dfbcc4df99c0d6b558d90822e
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Pluripotent stem cells have broad applications in regenerative medicine and offer ideal models for understanding the biological process of embryonic development and specific diseases. Studies suggest that the self-renewal and multi-lineage differenti
Externí odkaz:
https://doaj.org/article/c540c8f9814b4fc28b77f4a768aa6810