Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ji-Eun See"'
Autor:
Jong Il Kim, Jung Ki Yoon, Yongsub Kim, An Hee Jang, Ha Rim Shin, Gayoung Jang, Ji Eun See, Jiyeon Kweon
Publikováno v:
Molecular Therapy. 29:2001-2007
Although prime editors are a powerful tool for genome editing, which can generate various types of mutations such as nucleotide substitutions, insertions, and deletions in the genome without double-strand breaks or donor DNA, the conventional prime e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7a5226cd3a227b9692f17fcbb95fca
https://doi.org/10.1016/j.ymthe.2021.02.022
https://doi.org/10.1016/j.ymthe.2021.02.022
Autor:
Ji-Eun See, Gayoung Jang, Yongsub Kim, Gi-Jun Sung, Kyung-Chul Choi, Jin-Soo Kim, Inki Kim, Heon Seok Kim, Ha Rim Shin, Jiyeon Kweon, An-Hee Jang, Sojung Park
Publikováno v:
Nucleic Acids Research
CRISPR-based base editors (BEs) are widely used to induce nucleotide substitutions in living cells and organisms without causing the damaging DNA double-strand breaks and DNA donor templates. Cytosine BEs that induce C:G to T:A conversion and adenine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7d058dad095b7dd41318342f516d3f
https://doi.org/10.1093/nar/gkab052
https://doi.org/10.1093/nar/gkab052
Autor:
Yongsub Kim, Ji-Eun See, Ha Rim Shin, Jong Won Lee, An-Hee Jang, Woochang Lee, Jiyeon Kweon, Kyunggon Kim, Suhwan Chang
Publikováno v:
Oncogene
Genetic mutations in BRCA1, which is crucial for the process of DNA repair and maintenance of genomic integrity, are known to increase markedly the risk of breast and ovarian cancers. Clinical genetic testing has been used to identify new BRCA1 varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c374ee51eff719be160580a40451eb2
http://europepmc.org/articles/PMC6937211
http://europepmc.org/articles/PMC6937211
Publikováno v:
Journal of visualized experiments : JoVE. (168)
Recent studies have investigated the risks associated with BRCA1 gene mutations using various functional assessment methods such as fluorescent reporter assays, embryonic stem cell viability assays, and therapeutic drug-based sensitivity assays. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c920ba3bf193cb2ebeae65f5f02e7fb2
https://pubmed.ncbi.nlm.nih.gov/33720123
https://pubmed.ncbi.nlm.nih.gov/33720123
Publikováno v:
Journal of Visualized Experiments.
Recent studies have investigated the risks associated with BRCA1 gene mutations using various functional assessment methods such as fluorescent reporter assays, embryonic stem cell viability assays, and therapeutic drug-based sensitivity assays. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee329a02f121fc5ae5dc30dc876b7ee
https://doi.org/10.3791/61557
https://doi.org/10.3791/61557