Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ji-Bo Kang"'
Autor:
Shan-Liang Sun, Shi-Han Wu, Ji-Bo Kang, Yi-Yuan Ma, Lu Chen, Peng Cao, Liang Chang, Ning Ding, Xin Xue, Nian-Guang Li, Zhi-Hao Shi
Publikováno v:
Journal of Medicinal Chemistry. 65:7415-7437
Despite significant efficacy, one of the major limitations of small-molecule Bruton's tyrosine kinase (BTK) agents is the presence of clinically acquired resistance, which remains a major clinical challenge. This Perspective focuses on medicinal chem
Autor:
Lu Chen, Yu-Hao Cao, Li-Jin Yang, Yang Cheng, Yi-Yuan Ma, Ji-Bo Kang, Qing-Xin Wang, Nan Li, Xiao Yang, Shi-Han Wu, Yue Zhong, Xiao-Long Wang, Xin Xue, Ning Ding, Qiao-Li Liang, Liang Chang, He-Min Li, Jin-Ao Duan, Shan-Liang Sun, Nianguang Li, Zhi-Hao Shi
Publikováno v:
SSRN Electronic Journal.
Autor:
Yue Zhong, Hai-Qing Zhang, Juan Ji, Wen-Yu Wu, Xiao Yang, Ji-Bo Kang, Nan Li, Liang Chang, Xiang-Kai Meng, Shao-Peng Yu, Xiao-Long Wang, Shan-Liang Sun, Nian-Guang Li, Xin Xue
Publikováno v:
European journal of medicinal chemistry. 227
The ubiquitination of the hypoxia-inducible factor-1α (HIF-1α) is mediated by interacting with the von Hippel-Lindau protein (VHL), and is associated with cancer, chronic anemia, and ischemia. VHL, an E3 ligase, has been reported to degrade HIF-1 f