Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Ji-Bin Peng"'
Autor:
Ruiqi Cai, Lingyun Wang, Xiong Liu, Marek Michalak, Jingfeng Tang, Ji-Bin Peng, Xing-Zhen Chen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Cai et al discover an auto-inhibitory interaction between the S5 and S6 helices in the calcium-selective channel TRPV6. Molecular dynamics simulations predict that pathogenic mutation R532Q in S5 results in channel gain-of-function, which is confirme
Externí odkaz:
https://doaj.org/article/f84f1128838c439088a25fe4a20a4f1e
Autor:
Ruiqi Cai, Xiong Liu, Rui Zhang, Laura Hofmann, Wang Zheng, Md Ruhul Amin, Lingyun Wang, Qiaolin Hu, Ji-Bin Peng, Marek Michalak, Veit Flockerzi, Declan W. Ali, Xing-Zhen Chen, Jingfeng Tang
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101444- (2020)
Summary: Transient receptor potential vanilloid 6 (TRPV6), a calcium-selective channel possessing six transmembrane domains (S1-S6) and intracellular N and C termini, plays crucial roles in calcium absorption in epithelia and bone and is involved in
Externí odkaz:
https://doaj.org/article/f731de1cf53d4bdc887eda14047aaf09
Autor:
Yanqing Zhang, Yuan Zhang, Robert N Bone, Wanxing Cui, Ji-Bin Peng, Gene P Siegal, Hongjun Wang, Hongju Wu
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36675 (2012)
The non-β endocrine cells in pancreatic islets play an essential counterpart and regulatory role to the insulin-producing β-cells in the regulation of blood-glucose homeostasis. While significant progress has been made towards the understanding of
Externí odkaz:
https://doaj.org/article/e9917974b39c4006a69031247f852c58
Publikováno v:
Biochemical and Biophysical Research Communications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b2f9e9e792d6533713d5b791268031f
https://doi.org/10.1016/j.bbrc.2023.05.105
https://doi.org/10.1016/j.bbrc.2023.05.105
Autor:
Lingyun Wang, Ji-Bin Peng, Ruiqi Cai, Xiong Liu, Marek Michalak, Xing-Zhen Chen, Jingfeng Tang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology
Communications Biology
TRPV6, a Ca-selective channel, is abundantly expressed in the placenta, intestine, kidney and bone marrow. TRPV6 is vital to Ca homeostasis and its defective expression or function is linked to transient neonatal hyperparathyroidism, Lowe syndrome/De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638b1d7478b12bc994c688f9694d93f6
https://doaj.org/article/f84f1128838c439088a25fe4a20a4f1e
https://doaj.org/article/f84f1128838c439088a25fe4a20a4f1e
Publikováno v:
Gene
Calcium-selective channel TRPV6 (Transient Receptor Potential channel family, Vanilloid subfamily member 6) belongs to the TRP family of cation channels and plays critical roles in transcellular calcium (Ca(2+)) transport, reuptake of Ca(2+) into cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8777d7f1e90d87a23fa8c4c54df369d2
https://europepmc.org/articles/PMC8950124/
https://europepmc.org/articles/PMC8950124/
Publikováno v:
Polycystic Kidney Disease
Ji-Bin Peng
Ji-Bin Peng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb3c6e14c6ea11c872cd0899f8f22d4
https://doi.org/10.1201/9780429468834-5
https://doi.org/10.1201/9780429468834-5
Publikováno v:
Biochemistry. 58(16)
Kelch-like 3 (KLHL3) is a substrate adaptor of an E3 ubiquitin ligase complex that regulates the degradation of its substrates, including with-no-lysine [K] kinase 4 (WNK4). Mutations in KLHL3 are associated with pseudohypoaldosteronism type II (PHAI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8f08db3bbfa8762b667ebab22418a2
https://pubmed.ncbi.nlm.nih.gov/30931564
https://pubmed.ncbi.nlm.nih.gov/30931564
Autor:
Ji-Bin Peng, Lingyun Wang
Publikováno v:
Protein Science. 26:163-173
Interaction between the acidic motif (AM) of protein kinase WNK4 and the Kelch domain of KLHL3 are involved in the pathogenesis of pseudohypoaldosteronism type II, a hereditary form of hypertension. This interaction is disrupted by some disease-causi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d27fc2ebb62a90e25892bd871430f599
https://doi.org/10.1002/pro.3063
https://doi.org/10.1002/pro.3063
Autor:
Lingyun Wang, Ruiqi Cai, Laura Hofmann, Declan W. Ali, Marek Michalak, Jingfeng Tang, Ruhul Amin, Veit Flockerzi, Xing-Zhen Chen, Wang Zheng, Xiong Liu, Qiaolin Hu, Rui Zhang, Ji-Bin Peng
Publikováno v:
iScience
iScience, Vol 23, Iss 9, Pp 101444-(2020)
iScience, Vol 23, Iss 9, Pp 101444-(2020)
Summary Transient receptor potential vanilloid 6 (TRPV6), a calcium-selective channel possessing six transmembrane domains (S1-S6) and intracellular N and C termini, plays crucial roles in calcium absorption in epithelia and bone and is involved in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922ca4c3939d101f03fe7798d9ef8847
https://doi.org/10.1016/j.isci.2020.101444
https://doi.org/10.1016/j.isci.2020.101444