Zobrazeno 1 - 10
of 1 196
pro vyhledávání: '"Ji-An Liang"'
Autor:
Kevin Chih-Yang Huang, William Tzu-Liang Chen, Jia-Yi Chen, Chien-Yueh Lee, Chia-Hsin Wu, Chia-Ying Lai, Pei-Chen Yang, Ji-An Liang, An‑Cheng Shiau, K. S. Clifford Chao, Tao-Wei Ke
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Although irradiated induced-pluripotent stem cells (iPSCs) as a prophylactic cancer vaccine elicit an antitumor immune response, the therapeutic efficacy of iPSC-based cancer vaccines is not promising due to their insufficient antigenicity a
Externí odkaz:
https://doaj.org/article/f7f837b5bb3344b482c12fb402089cc0
Autor:
Kevin Chih-Yang Huang, Tao-Wei Ke, Chia-Ying Lai, Wei-Ze Hong, Hsin-Yu Chang, Chien-Yueh Lee, Chia-Hsin Wu, Shu-Fen Chiang, Ji-An Liang, Jhen-Yu Chen, Pei-Chen Yang, William Tzu-Liang Chen, Eric Y. Chuang, K.S. Clifford Chao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116958- (2024)
The therapeutic efficacy of immunotherapy is limited in the majority of colorectal cancer patients due to the low mutational and neoantigen burdens in this immunogenically “cold” microsatellite stability-colorectal cancer (MSS-CRC) cohort. Here,
Externí odkaz:
https://doaj.org/article/8ae011ff13d845e9af1d8e8f1de4e7c2
Autor:
Ji-An Liang, Hsin-Yu Chang, Kevin Chih-Yang Huang, Shu-Fen Chiang, Wei-Ze Hong, Jhen-Yu Chen, Pei-Chih Lee, Tao-Wei Ke, Shin-Lei Peng, An‑Cheng Shiau, Tsung-Wei Chen, Pei-Chen Yang, William Tzu-Liang Chen, K S Clifford Chao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Cancer-intrinsic type I interferon (IFN-I) production triggered by radiotherapy (RT) is mainly dependent on cytosolic double-stranded DNA (dsDNA)-mediated cGAS/STING signaling and increases cancer immunogenicity and enhances the antitumor
Externí odkaz:
https://doaj.org/article/04f35a576e1d4e42ae0eae914b4b76f6
Autor:
Kevin Chih-Yang Huang, Shu-Fen Chiang, Pei-Chun Lin, Wei-Ze Hong, Pei-Chen Yang, Hui-Ping Chang, Shin-Lei Peng, Tsung-Wei Chen, Tao-Wei Ke, Ji-An Liang, William Tzu-Liang Chen, K. S. Clifford Chao
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract ATP and its receptor P2RX7 exert a pivotal effect on antitumor immunity during chemotherapy-induced immunogenic cell death (ICD). Here, we demonstrated that TNFα-mediated PANX1 cleavage was essential for ATP release in response to chemother
Externí odkaz:
https://doaj.org/article/9b94d1b51f6c4247a382ea20f1a4efd8
Autor:
Kevin Chih-Yang Huang, Tao-Wei Ke, Jia-Yi Chen, Wei-Ze Hong, Shu-Fen Chiang, Chia-Ying Lai, Tsung-Wei Chen, Pei-Chen Yang, Liang-Chi Chen, Ji-An Liang, William Tzu-Liang Chen, K. S. Clifford Chao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Regional lymph node metastasis is an important predictor for survival outcome and an indicator for postoperative adjuvant chemotherapy in patients with colorectal cancer. Even with advances in adjuvant chemotherapeutic regimens, 5-year dista
Externí odkaz:
https://doaj.org/article/805466ca437449f18933c47295fdf9dd
Publikováno v:
Canadian Respiratory Journal, Vol 2024 (2024)
Background. The effectiveness of definitive radiotherapy (RT) for patients with clinical stage IIIB or IIIC lung adenocarcinoma and epidermal growth factor receptor (EGFR) mutations who received first- or second-generation EGFR tyrosine kinase inhibi
Externí odkaz:
https://doaj.org/article/c13550cd03a8452298fbb8974c8a3f6b
Autor:
Kevin Chih-Yang Huang, Shu-Fen Chiang, Hsin-Yu Chang, William Tzu-Liang Chen, Pei-Chen Yang, Tsung-Wei Chen, Ji-An Liang, An‑Cheng Shiau, Tao-Wei Ke, K. S. Clifford Chao
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-12 (2022)
Abstract Radiotherapy (RT) mainly elicits antitumor immunity via the cGAS/STING axis for type I interferon (IFN) production. However, dysregulation of cGAS/STING constrains radiotherapy-induced antitumor immunity and type I IFN-dependent cell death a
Externí odkaz:
https://doaj.org/article/30fde6c7ddcd43b5a24c83e8815e09b7
Autor:
Hao Xiang Chen, Li-Hsien Tsai, Chao-Hsiang Chang, Hsi-Chin Wu, Ching-Chan Lin, Che-Hung Lin, Chin-Chung Yeh, Chi-Rei Yang, Chi-Shun Lien, Yi-Huei Chang, Ji-An Liang, Guan-Heng Chen, Po-Jen Hsiao, Po-Fan Hsieh, Chi-Ping Huang
Publikováno v:
Cancers, Vol 15, Iss 13, p 3516 (2023)
Metastatic castration-resistant prostate cancer (mCRPC) is a progressive stage of prostate cancer that often spreads to the bone. Radium-223, a bone-targeting radiopharmaceutical, has been shown to improve the overall survival in mCRPC in patients wi
Externí odkaz:
https://doaj.org/article/e5afeb033cc14f2caa3eec04eaacec0b
Autor:
Ting-Chun Lin MD, Chi-Hsien Huang MD, Ming-Yu Lien MD, Fu-Ming Cheng MD, Kai-Chiun Li, Chih-Yuan Lin, Ying-Chun Lin, Ji-An Liang, Ti-Hao Wang MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
Introduction: Aim of this retrospective cohort study is to evaluate the prognostic value of tumor volume reduction rate status post-induction chemotherapy in locally advanced head and neck squamous cell carcinoma. Methods: Patients newly diagnosed fr
Externí odkaz:
https://doaj.org/article/47cbe104f7f44e34997b9c7afe32321d
Autor:
Hsin-Yi Cheng, Ji-An Liang, Yao-Ching Hung, Lian-Shung Yeh, Wei-Chun Chang, Wu-Chou Lin, Shang-Wen Chen
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 60, Iss 1, Pp 111-118 (2021)
Objective: To evaluate efficacy of stereotactic body radiotherapy (SBRT) for pelvic boost irradiation in gynecological cancer patients with pelvic recurrence or with intact uterus unsuitable for brachytherapy. Materials and methods: We retrospectivel
Externí odkaz:
https://doaj.org/article/88b2afacafd143428013dcc5c418504c