Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Ji Yih Chen"'
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-21 (2024)
Background Systemic lupus erythematosus (SLE) is distinguished by an extensive range of clinical heterogeneity with unpredictable disease flares and organ damage. This research investigates the potential of aberrant signatures on T cell genes, solubl
Externí odkaz:
https://doaj.org/article/5a771ff871154614bc7742a1b34727ce
Publikováno v:
Cells, Vol 13, Iss 5, p 403 (2024)
Co-inhibitory receptors (Co-IRs) are essential in controlling the progression of immunopathology in rheumatoid arthritis (RA) by limiting T cell activation. The objective of this investigation was to determine the phenotypic expression of Co-IR T cel
Externí odkaz:
https://doaj.org/article/35321ed154bb4e6d9af7dc22f24ba8ee
Publikováno v:
Journal of the Formosan Medical Association, Vol 121, Iss 7, Pp 1283-1294 (2022)
Background/Purpose: The intergenic SNP rs10865331 at 2p15 was identified as a major risk factor for ankylosing spondylitis (AS) susceptibility in genome-wide association studies (GWAS). B3GNT2 gene regulates polylactosamine synthesis is potentially f
Externí odkaz:
https://doaj.org/article/b4a6831338144b80ad5c6bcf95c5ec0c
Publikováno v:
Biomedical Journal, Vol 42, Iss 2, Pp 124-130 (2019)
Background: Ankylosing spondylitis (AS) is an inflammatory autoimmune disorder that manifested with sacroiliitis at its early stage and developed extensive inflammation with syndesmophytes of the lumbar, thoracic and cervical spines at its later stag
Externí odkaz:
https://doaj.org/article/c24ed07d1ae744c09b9d9ecaf96a1518
Autor:
Chin-Man Wang, Ming-Kun Liu, Yeong-Jian Jan Wu, Jing-Chi Lin, Jian-Wen Zheng, Jianming Wu, Ji-Yih Chen
Publikováno v:
Cells, Vol 11, Iss 15, p 2427 (2022)
Epistasis of ERAP1 single nucleotide variations (SNVs) and HLA-B27 has been linked to ankylosing spondylitis susceptibility (AS). The current study examined how prevalent ERAP1 allelic variants (SNV haplotypes) in Taiwan affect ERAP1 functions and AS
Externí odkaz:
https://doaj.org/article/1ed080f7585a4fe088dbaed0ddf1affe
Autor:
Ji-Yih Chen, Chin-Man Wang, Tai-Di Chen, Yeong-Jian Jan Wu, Jing-Chi Lin, Ling Ying Lu, Jianming Wu
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Type III interferons (IFNs) or IFN-λs are the newly discovered cytokines that primarily target the cells of epithelial and myeloid lineages, which are major components of kidneys. The current study aimed to investigate whether IF
Externí odkaz:
https://doaj.org/article/feef294715434717b7c1911f8fe2dc8b
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 50, Iss 6, Pp 857-862 (2017)
Background and aim: Raynaud's phenomenon (RP) is a microvascular disorder characterized by episodic peripheral vasospasm and ischemia and is commonly found in patients with autoimmune diseases (AID). The vasomotor homoeostasis and endothelial cells d
Externí odkaz:
https://doaj.org/article/a2bf7e1cba564a11bb74896eaeb46868
Publikováno v:
Journal of the Formosan Medical Association. 121:1283-1294
Background/Purpose The intergenic SNP rs10865331 at 2p15 was identified as a major risk factor for ankylosing spondylitis (AS) susceptibility in genome-wide association studies (GWAS). B3GNT2 gene regulates polylactosamine synthesis is potentially fu
Autor:
Syh-Jae Lin, Ming-Ling Kuo, Hsiu-Shan Hsiao, Pei-Tzu Lee, Wen-I Lee, Ji-Yih Chen, Jing-Long Huang
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Natural killer cells and NKT-like cells are the first line immune defense against tumor and virus infection. Deficient NK and NKT-like cell effector function may contribute to increased susceptibility to infection in SLE patients. We sought to examin
Externí odkaz:
https://doaj.org/article/b6620691ee4440908663b9499e422f95
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Ankylosing spondylitis (AS) is a chronic inflammatory disease that leads to spinal ankylosis. The receptor activator of the nuclear factor-kappa (RANK), RANK ligand, and osteoprotegerin (OPG) (RANK/RANKL/OPG) pathway plays critical roles in bone meta
Externí odkaz:
https://doaj.org/article/af91d82402034600b8e0b42709bfdf5e