Zobrazeno 1 - 10
of 383
pro vyhledávání: '"Ji Yeoun Lee"'
Autor:
Sojin Kim, Tamrin Chowdhury, Hyeon Jong Yu, Jee Ye Kahng, Chae Eun Lee, Seung Ah. Choi, Kyung-Min Kim, Ho Kang, Joo Ho Lee, Soon-Tae Lee, Jae-Kyung Won, Kyung Hyun Kim, Min-Sung Kim, Ji Yeoun Lee, Jin Wook Kim, Yong-Hwy Kim, Tae Min Kim, Seung Hong Choi, Ji Hoon Phi, Young-Kyoung Shin, Ja-Lok Ku, Sungyoung Lee, Hongseok Yun, Hwajin Lee, Dokyoung Kim, Kyoungmi Kim, Junho K. Hur, Sung-Hye Park, Seung-Ki Kim, Chul-Kee Park
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background The activation of the telomere maintenance mechanism (TMM) is one of the critical drivers of cancer cell immortality. In gliomas, TERT expression and TERT promoter mutation are considered to reliably indicate telomerase activation
Externí odkaz:
https://doaj.org/article/f8118b5a57eb4e34a8c2820b80aa8ed9
Autor:
Seung Ah Choi, Eun Jung Koh, Ryong Nam Kim, Jung Woo Byun, Ji Hoon Phi, Jeyul Yang, Kyu-Chang Wang, Ae Kyung Park, Do Won Hwang, Ji Yeoun Lee, Seung-Ki Kim
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Extracellular vesicles (EVs) secreted by tumours, including exosomes, are important factors that regulate cell–cell interactions in oncogenesis. Although EV studies are ongoing, the biological understanding of EV-miRNAs derived
Externí odkaz:
https://doaj.org/article/44a9270bcd0243589b741a64885dff43
Autor:
Hee Yeon Kim, Seung Ah Choi, Eun Jung Koh, Kyung Hyun Kim, Ji Hoon Phi, Ji Yeoun Lee, Seung-Ki Kim
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeAtypical teratoid/rhabdoid tumor (AT/RT) is arising typically in young children and is associated with a dismal prognosis which there is currently no curative chemotherapeutic regimen. Based on previous studies showing high histone deacetylase
Externí odkaz:
https://doaj.org/article/8117c476af5f4a4cab8600be0254996e
Autor:
Ji Hoon Phi, Choong-Hyun Sun, Se-Hoon Lee, Seungmook Lee, Inho Park, Seung Ah Choi, Sung-Hye Park, Ji Yeoun Lee, Kyu-Chang Wang, Seung-Ki Kim, Hongseok Yun, Chul-Kee Park
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Atypical teratoid/rhabdoid tumors (AT/RTs) are highly malignant brain tumors with inactivation of the SMARCB1 gene, which play a critical role in genomic transcriptional control. In this study, we analyzed the genomic and transcri
Externí odkaz:
https://doaj.org/article/2f32b8ed164c419aa612e74e941e07c5
Autor:
Ae Kyung Park, Ji Yeoun Lee, Heesun Cheong, Vijay Ramaswamy, Sung-Hye Park, Marcel Kool, Ji Hoon Phi, Seung Ah Choi, Florence Cavalli, Michael D. Taylor, Seung-Ki Kim
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background Using a pathway-focused approach, we aimed to provide a subgroup-specific basis for finding novel therapeutic strategies and further refinement of the risk stratification in pediatric medulloblastoma. Method Based on genome-wide C
Externí odkaz:
https://doaj.org/article/3eb36ba49c194c33997523b632a8b2c4
Autor:
Chung Kwon Kim, Jeong-Seob Won, Jae Yeol An, Ho Jin Lee, Ah-Jin Nam, Hyun Nam, Ji Yeoun Lee, Kyung-Hoon Lee, Sun-Ho Lee, Kyeung Min Joo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4267 (2022)
The limited capability of regeneration in the human central nervous system leads to severe and permanent disabilities following spinal cord injury (SCI) while patients suffer from no viable treatment option. Adult human neural stem cells (ahNSCs) are
Externí odkaz:
https://doaj.org/article/ddc40896cc274eda91785cae594b2824
Autor:
Liana Nobre, Michal Zapotocky, Sara Khan, Kohei Fukuoka, Adriana Fonseca, Tara McKeown, David Sumerauer, Ales Vicha, Wieslawa A. Grajkowska, Joanna Trubicka, Kay Ka Wai Li, Ho-Keung Ng, Luca Massimi, Ji Yeoun Lee, Seung-Ki Kim, Shayna Zelcer, Alexandre Vasiljevic, Cécile Faure-Conter, Peter Hauser, Boleslaw Lach, Marie-Lise van Veelen-Vincent, Pim J. French, Erwin G. Van Meir, William A. Weiss, Nalin Gupta, Ian F. Pollack, Ronald L. Hamilton, Amulya A. Nageswara Rao, Caterina Giannini, Joshua B. Rubin, Andrew S. Moore, Lola B. Chambless, Rajeev Vibhakar, Young Shin Ra, Maura Massimino, Roger E. McLendon, Helen Wheeler, Massimo Zollo, Veronica Ferruci, Toshihiro Kumabe, Claudia C. Faria, Jaroslav Sterba, Shin Jung, Enrique López-Aguilar, Jaume Mora, Carlos G. Carlotti, James M. Olson, Sarah Leary, Jason Cain, Lenka Krskova, Josef Zamecnik, Cynthia E. Hawkins, Uri Tabori, Annie Huang, Ute Bartels, Paul A. Northcott, Michael D. Taylor, Stephen Yip, Jordan R. Hansford, Eric Bouffet, Vijay Ramaswamy
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100038- (2020)
Summary: Over the past decade, wingless-activated (WNT) medulloblastoma has been identified as a candidate for therapy de-escalation based on excellent survival; however, a paucity of relapses has precluded additional analyses of markers of relapse.
Externí odkaz:
https://doaj.org/article/fe064d5dfe04450eab73d80ac7fe7dce
Autor:
Hye Youn Sung, Ji Yeoun Lee, Ae Kyung Park, Youn Joo Moon, Inho Jo, Eun-Mi Park, Kyu-Chang Wang, Ji Hoon Phi, Jung-Hyuck Ahn, Seung-Ki Kim
Publikováno v:
Journal of Stroke, Vol 20, Iss 3, Pp 350-361 (2018)
Background and Purpose The pathogenesis of moyamoya disease (MMD) remains poorly understood, and no reliable molecular biomarkers for MMD have been identified to date. The present study aimed to identify epigenetic biomarkers for use in the diagnosis
Externí odkaz:
https://doaj.org/article/aef8162b0f3d454a9cfa1fa79f392332
Autor:
Chanhee Lee, Joongyub Lee, Seung Ah Choi, Seung-Ki Kim, Kyu-Chang Wang, Sung-Hye Park, Se Hoon Kim, Ji Yeoun Lee, Ji Hoon Phi
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Recent progress in molecular analysis has advanced the understanding of medulloblastoma (MB) and is anticipated to facilitate management of the disease. MB is composed of 4 molecular subgroups: WNT, SHH, Group 3, and Group 4. Macr
Externí odkaz:
https://doaj.org/article/b4cf2f4908fa434685fe39af88c11971
Publikováno v:
Translational Oncology, Vol 8, Iss 5, Pp 376-386 (2015)
The long-term clinical outcome of pediatric intracranial epepdymoma is poor with a high rate of recurrence. One of the main reasons for this poor outcome is the tumor’s inherent resistance to chemotherapy. Signal transducer and activator of transcr
Externí odkaz:
https://doaj.org/article/51406322ef5e470eb98d550ddef77e2d