Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Ji Suk Chang"'
Autor:
Ji Suk Chang
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Brown adipocytes is a specialized fat cell that dissipates nutrient-derived chemical energy in the form of heat, instead of ATP synthesis. This unique feature provides a marked capacity for brown adipocyte mitochondria to oxidize substrates independe
Externí odkaz:
https://doaj.org/article/5ef72b46ce684db39fe45a9ffcdaa5dc
Autor:
Sujoy Ghosh, Chul-Hong Park, Jisu Lee, Nathan Lee, Rui Zhang, Clara Huesing, Dorien Reijnders, Jennifer Sones, Heike Münzberg, Leanne Redman, Ji Suk Chang
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Brown adipose tissue (BAT) is specialized to dissipate energy in the form of heat. BAT-mediated heat production in rodents and humans is critical for effective temperature adaptation of newborns to the extrauterine environment imm
Externí odkaz:
https://doaj.org/article/856288f4ffc7472480217c7987fc85ba
Autor:
Jihyun Kim, Jiyoung Moon, Chul-Hong Park, Jisu Lee, Helia Cheng, Z. Elizabeth Floyd, Ji Suk Chang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α regulate metabolic adaptation by modulating many gene programs. Selective ablation of PGC-1α attenuates diet-induced obesity through enhancing fatty acid oxidation and th
Externí odkaz:
https://doaj.org/article/4153d82f4dba4c91a406693aa85f7854
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Brown and beige adipocytes are specialized to dissipate energy as heat. Sgk2, encoding a serine/threonine kinase, has been identified as a brown and beige adipocyte-specific gene in rodents and humans; however, its function in brown/beige adipocytes
Externí odkaz:
https://doaj.org/article/28532b24e7b148e1b07cb4dd92d85871
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The central nervous system controls feeding behavior and energy expenditure in response to various internal and external stimuli to maintain energy balance. Here we report that the newly identified transcription factor zinc finger and BTB domain cont
Externí odkaz:
https://doaj.org/article/91ebcad2805b47b69623b1d2aea29e78
Autor:
Jihyun Kim, Min Sung Park, Kyoungsoo Ha, Chulhong Park, Jisu Lee, Randall L. Mynatt, Ji Suk Chang
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1660-1670 (2018)
Transcriptional coactivator PPAR γ coactivator (PGC)-1α and its splice variant N-terminal (NT)-PGC-1α mediate transcriptional regulation of brown adipose tissue (BAT) thermogenesis in response to changes in ambient temperature. PGC-1α is dispensa
Externí odkaz:
https://doaj.org/article/10e836d918fa42b9a31f69951e7e66ff
Autor:
Ji Suk Chang, Kyoungsoo Ha
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0195007 (2018)
Peroxisome proliferator-activated receptor gamma (PPARγ) is a key regulator of brown adipocyte differentiation and thermogenesis. The PPARγ gene produces two isoforms, PPARγ1 and PPARγ2. PPARγ2 is identical to PPARγ1 except for additional 30 am
Externí odkaz:
https://doaj.org/article/9de6b769431d4844975f2b43b1e6c9bb
Autor:
Jihyun Kim, Vivian E Fernand, Tara M Henagan, Jeho Shin, Peter Huypens, Susan Newman, Thomas W Gettys, Ji Suk Chang
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159990 (2016)
The β3-adrenergic receptor (AR) signaling pathway is a major component of adaptive thermogenesis in brown and white adipose tissue during cold acclimation. The β3-AR signaling highly induces the expression of transcriptional coactivator PGC-1α and
Externí odkaz:
https://doaj.org/article/14cc82e4d4674e62a87353c90829f043
Publikováno v:
PPAR Research, Vol 2012 (2012)
Brown fat expresses two PGC-1α isoforms (PGC-1α and NT-PGC-1α) and both play a central role in the regulation of cellular energy metabolism and adaptive thermogenesis by interacting with a wide range of transcription factors including PPARγ, PPAR
Externí odkaz:
https://doaj.org/article/33a0316af5b74b63a5a060edf65c3eed
Autor:
Min-Suk Jung, Ji-Suk Chang
Publikováno v:
The Korean Journal of Growth and Development. 31:45-53