Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ji Seul Han"'
Autor:
Yong Geun Jeon, Hahn Nahmgoong, Jiyoung Oh, Dabin Lee, Dong Wook Kim, Jane Eunsoo Kim, Ye Young Kim, Yul Ji, Ji Seul Han, Sung Min Kim, Jee Hyung Sohn, Won Taek Lee, Sun Won Kim, Jeu Park, Jin Young Huh, Kyuri Jo, Je-Yoel Cho, Jiyoung Park, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract In mammals, brown adipose tissue (BAT) and inguinal white adipose tissue (iWAT) execute sequential thermogenesis to maintain body temperature during cold stimuli. BAT rapidly generates heat through brown adipocyte activation, and further iWA
Externí odkaz:
https://doaj.org/article/893240ee8ebd4861b31b0ae25b073103
Autor:
Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Jeehye Choi, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Thermogenic adipocytes maintain body temperature in response to cold, but how this is tuned during cold and re-warming is unclear. Here, the authors show HIF2α inhibits beige adipocyte retention, regulating PKA catalysis to control dynamic adipocyte
Externí odkaz:
https://doaj.org/article/c719b3a3e9594fb9a44b17d3954cfdae
Autor:
Jinuk Kong, Yul Ji, Yong Geun Jeon, Ji Seul Han, Kyung Hee Han, Jung Hyun Lee, Gung Lee, Hagoon Jang, Sung Sik Choe, Myriam Baes, Jae Bum Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Lipid droplets are organelles that regulate lipid metabolism but if organellar contacts play a role during lipolysis is unclear. Here, the authors show that peroxisomes and peroxisomal protein PEX5 play pivotal roles in the spatial and temporal regul
Externí odkaz:
https://doaj.org/article/ca6fe38e928249d98547a91aacc29c51
Publikováno v:
Contact, Vol 3 (2020)
Lipid droplets (LDs) are dynamic subcellular organelles which play critical roles for lipid homeostasis upon change of nutritional state. Although several organelles such as mitochondria and peroxisomes are involved in lipid metabolism, physiological
Externí odkaz:
https://doaj.org/article/eb0424589e174de5af6abc9d03743e15
Autor:
Ye Young Kim, Hagoon Jang, Gung Lee, Yong Geun Jeon, Jee Hyung Sohn, Ji Seul Han, Won Taek Lee, Jeu Park, Jin Young Huh, Hahn Nahmgoong, Sang Mun Han, Jeesoo Kim, Minwoo Pak, Sun Kim, Jong-Seo Kim, Jae Bum Kim
Publikováno v:
Diabetes. 71:1373-1387
Excessive hepatic glucose production (HGP) is a key factor promoting hyperglycemia in diabetes. Hepatic cryptochrome 1 (CRY1) plays an important role in maintaining glucose homeostasis by suppressing forkhead box protein O1 (FOXO1)-mediated HGP. Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c2b3231822891cb3d656ff01634366
https://doi.org/10.2337/db21-0649
https://doi.org/10.2337/db21-0649
Autor:
Ji Seul Han
Publikováno v:
Molecules and Cells. 45:534-536
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e5ba6a1aa3ed43cbfe8cbd864a7137
https://doi.org/10.14348/molcells.2022.0106
https://doi.org/10.14348/molcells.2022.0106
Autor:
Chang-Yun Cho, Isaac Park, Ji Seul Han, Jee Hyung Sohn, Yong Geun Jeon, Sangsoo Lim, Hyun-Woo Rhee, Sang Mun Han, Hahn Nahmgoong, Sun Kim, Yul Ji, Jae Bum Kim
Publikováno v:
Diabetes. 70:2756-2770
Reactive oxygen species (ROS) are associated with various roles of brown adipocytes. Glucose-6-phosphate dehydrogenase (G6PD) controls cellular redox potentials by producing NADPH. Although G6PD upregulates cellular ROS levels in white adipocytes, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf55dbde2091053f8802ee3db1592a4
https://doi.org/10.2337/db21-0272
https://doi.org/10.2337/db21-0272
Autor:
Kyung Cheul Shin, Jin Young Huh, Yul Ji, Ji Seul Han, Sang Mun Han, Jeu Park, Hahn Nahmgoong, Won Taek Lee, Yong Geun Jeon, Bohyeon Kim, Chanyoon Park, Heonjoong Kang, Sung Sik Choe, Jae Bum Kim
Publikováno v:
Cell Reports. 41:111806
In mammals, brown adipose tissue (BAT) is specialized to conduct non-shivering thermogenesis for survival under cold acclimation. Although emerging evidence suggests that lipid metabolites are essential for heat generation in cold-activated BAT, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4567cea930ae8f29dd712072e21d663c
https://doi.org/10.1016/j.celrep.2022.111806
https://doi.org/10.1016/j.celrep.2022.111806
Autor:
Jeu Park, Do Hoon Lee, Seokjin Ham, Jiyoung Oh, Jung-Ran Noh, Yun Kyung Lee, Yoon Jeong Park, Gung Lee, Sang Mun Han, Ji Seul Han, Ye Young Kim, Yong Geun Jeon, Han Nahmgoong, Kyung Cheul Shin, Sung Min Kim, Sung Hee Choi, Chul-Ho Lee, Jiyoung Park, Tae Young Roh, Sun Kim, Jae Bum Kim
Publikováno v:
Nature metabolism. 4(7)
DNA methylation is a crucial epigenetic modification in the establishment of cell-type-specific characteristics. However, how DNA methylation is selectively reprogrammed at adipocyte-specific loci during adipogenesis remains unclear. Here, we show th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfaff0d8fceb9a2b779488f4afe2dce
https://pubmed.ncbi.nlm.nih.gov/35788760
https://pubmed.ncbi.nlm.nih.gov/35788760
Autor:
Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Jeehye Choi, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, Jae Bum Kim
Publikováno v:
Nature communications. 13(1)
Thermogenic adipocytes generate heat to maintain body temperature against hypothermia in response to cold. Although tight regulation of thermogenesis is required to prevent energy sources depletion, the molecular details that tune thermogenesis are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d6938eb922a3d1a71c1314386b6d63
https://pubmed.ncbi.nlm.nih.gov/35672324
https://pubmed.ncbi.nlm.nih.gov/35672324