Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ji Na, Kong"'
Autor:
Ji-Na Kong, Zhihui Zhu, Yutaka Itokazu, Guanghu Wang, Michael B. Dinkins, Liansheng Zhong, Hsuan-Pei Lin, Ahmed Elsherbini, Silvia Leanhart, Xue Jiang, Haiyan Qin, Wenbo Zhi, Stefka D. Spassieva, Erhard Bieberich
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 3, Pp 488-506 (2018)
We reported that amyloid β peptide (Aβ42) activated neutral SMase 2 (nSMase2), thereby increasing the concentration of the sphingolipid ceramide in astrocytes. Here, we show that Aβ42 induced mitochondrial fragmentation in wild-type astrocytes, bu
Externí odkaz:
https://doaj.org/article/2e953d848a4e4bdf95da608fbf87f121
Autor:
Liansheng Zhong, Ji Na Kong, Michael B. Dinkins, Silvia Leanhart, Zhihui Zhu, Stefka D. Spassieva, Haiyan Qin, Hsuan-Pei Lin, Ahmed Elsherbini, Rebecca Wang, Xue Jiang, Mariana Nikolova-Karakashian, Guanghu Wang, Erhard Bieberich
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 795-804 (2018)
Sphingolipids are key signaling lipids in cancer. Genome-wide studies have identified neutral SMase-2 (nSMase2), an enzyme generating ceramide from SM, as a potential repressor for hepatocellular carcinoma. However, little is known about the sphingol
Externí odkaz:
https://doaj.org/article/5fdac2cab1a34351b8c39e1c023183be
Autor:
Carlos Pardo-Pastor, Daniel P. Denning, Nolan Tucker, Vivek K. Dwivedi, Rita Droste, Jody Rosenblatt, Ji Na Kong, H. Robert Horvitz
Publikováno v:
Nature. 593:591-596
Cell extrusion is a mechanism of cell elimination that is used by organisms as diverse as sponges, nematodes, insects and mammals1–3. During extrusion, a cell detaches from a layer of surrounding cells while maintaining the continuity of that layer
Autor:
Vivek K, Dwivedi, Carlos, Pardo-Pastor, Rita, Droste, Ji Na, Kong, Nolan, Tucker, Daniel P, Denning, Jody, Rosenblatt, H Robert, Horvitz
Publikováno v:
Nature. 593(7860)
Cell extrusion is a mechanism of cell elimination that is used by organisms as diverse as sponges, nematodes, insects and mammals
Autor:
Mariana Nikolova-Karakashian, Zhihui Zhu, Erhard Bieberich, Xue Jiang, Liansheng Zhong, Ahmed Elsherbini, Hsuan-Pei Lin, Silvia Leanhart, Stefka D. Spassieva, Michael B. Dinkins, Ji Na Kong, Guanghu Wang, Rebecca Wang, Haiyan Qin
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 795-804 (2018)
Sphingolipids are key signaling lipids in cancer. Genome-wide studies have identified neutral SMase-2 (nSMase2), an enzyme generating ceramide from SM, as a potential repressor for hepatocellular carcinoma. However, little is known about the sphingol
Publikováno v:
Preparative Biochemistry & Biotechnology. 47:1037-1042
Agarase catalyzes the hydrolysis of agar, which is primarily used as a medium for microbiology, various food additives, and new biomass materials. In this study, we described the expression of the synthetic gene encoding β-agarase from Agarivorans a
Autor:
Gu Zhu, Guanghu Wang, Jacek Bielawski, Michael B. Dinkins, Qian He, Stefka D. Spassieva, Kara Hardin, Ji Na Kong, Erhard Bieberich, Tarik Mujadzic
Publikováno v:
Molecular Biology of the Cell
Cilia are important organelles formed by cell membrane protrusions; however, little is known about their regulation by membrane lipids. A novel, evolutionarily conserved activation mechanism for GSK3 by the sphingolipid (phyto)ceramide is characteriz
Autor:
Stefka D. Spassieva, Xue Jiang, Ahmed Elsherbini, Yutaka Itokazu, Wenbo Zhi, Liansheng Zhong, Haiyan Qin, Silvia Leanhart, Michael B. Dinkins, Hsuan Pei Lin, Erhard Bieberich, Ji Na Kong, Guanghu Wang, Zhihui Zhu
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 3, Pp 488-506 (2018)
We reported that amyloid β peptide (Aβ(42)) activated neutral SMase 2 (nSMase2), thereby increasing the concentration of the sphingolipid ceramide in astrocytes. Here, we show that Aβ(42) induced mitochondrial fragmentation in wild-type astrocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9311dadba8dd07b2ed2963a9d151da6d
https://europepmc.org/articles/PMC5832933/
https://europepmc.org/articles/PMC5832933/
Publikováno v:
Journal of the Science of Food and Agriculture. 96:3202-3206
BACKGROUND The sweetness of brazzein, one of the known sweet proteins, is dependent on charges and/or structures of its specific amino acid side chains. As the residues in the C-terminus of brazzein are known to play a critical role in sweetness, the
Autor:
Qian He, Ji Na Kong, Somsankar Dasgupta, Stefka D. Spassieva, Gu Zhu, Austin Kim, Guanghu Wang, Michael B. Dinkins, Erhard Bieberich
Publikováno v:
International Journal of Cancer. 137:1610-1620
Many breast cancer cells acquire multidrug resistance (MDR) mediated by ABC transporters such as breast cancer resistance protein (BCRP/ABCG2). Here we show that incubation of human breast cancer MDA-MB-231 cells with farnesoid X receptor antagonist