Výsledky vyhledávání - "Ji Kang Fang"

Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

Autor: Edison Mejia, Miguel Garcia-Diaz, Jeelan Basha, Hiroshi Nakagawa, Eric F. Rappaport, Andres J. Klein-Szanto, Narayan G. Avadhani, Tapas K. Kundu, Satish Srinivasan, Ji-Kang Fang, Kip E. Guja, Manti Guha, Gordon Ruthel, Brett A. Kaufman, F. Brad Johnson, M. Rebecca Glineburg

Publikováno v: Cell Discovery
Cell Discovery, Vol 5, Iss 1, Pp 1-1 (2019)

Reduced mitochondrial DNA copy number, mitochondrial DNA mutations or disruption of electron transfer chain complexes induce mitochondria-to-nucleus retrograde signaling, which induces global change in nuclear gene expression ultimately contributing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf54607837e434cf562ef83c4d90c15e
https://pubmed.ncbi.nlm.nih.gov/27990297

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Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Mitochondrion-targeted Cytochrome P450 2D6

Autor: Ji-Kang Fang, Shilpee Singh, Qian Cheng, Prachi Bajpai, Weigang Tang, Martha V. Martin, Narayan G. Avadhani, F. Peter Guengerich, Seema Bansal, Michelle C Sangar, Goutam Chowdhury

Publikováno v: Journal of Biological Chemistry. 288:4436-4451

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxic side product formed in the chemical synthesis of desmethylprodine opioid analgesic, which induces Parkinson disease. Monoamine oxidase B, present in the mitochondrial outer membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14827d64f16ab307758fc97a26c44b2c
https://doi.org/10.1074/jbc.m112.402123

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HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression

Autor: Jeelan Basha, Tapas K. Kundu, Edison Mejia, Hiroshi Nakagawa, Manti Guha, Gordon Ruthel, Ji-Kang Fang, Narayan G. Avadhani, Eric F. Rappaport, Kip E. Guja, Miguel Garcia-Diaz, Andres J. Klein-Szanto, Brett A. Kaufman, Andres Klein Szanto, M. Rebecca Glineburg, F. Brad Johnson, Satish Srinivasan

Publikováno v: Cell Discovery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf6c7eaee5024621681293abea6532f
https://pubmed.ncbi.nlm.nih.gov/31098295

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Leucine-Rich Pentatricopeptide-Repeat Containing Protein Regulates Mitochondrial Transcription

Autor: Erzsebet Polyak, Ji Kang Fang, Marni J. Falk, Neal Sondheimer, Narayan G. Avadhani

Publikováno v: Biochemistry. 49:7467-7473

Mitochondrial function depends upon the coordinated expression of the mitochondrial and nuclear genomes. Although the basal factors that carry out the process of mitochondrial transcription are known, the regulation of this process is incompletely un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4e2ba955fb8109d19efe0baf194137
https://doi.org/10.1021/bi1008479

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Bimodal Protein Targeting through Activation of Cryptic Mitochondrial Targeting Signals by an Inducible Cytosolic Endoprotease

Autor: Ji-Kang Fang, Satish Srinivasan, Ettickan Boopathi, Narayan G. Avadhani

Publikováno v: Molecular Cell. 32:32-42

Bimodal targeting of the endoplasmic reticular protein, cytochrome P4501A1 (CYP1A1), to mitochondria involves activation of a cryptic mitochondrial targeting signal through endoprotease processing of the protein. Here, we characterized the endoprotea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e175970f08bca8fe26ff0b16c57eb9
https://doi.org/10.1016/j.molcel.2008.09.008

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Site specific phosphorylation of cytochromecoxidase subunits I, IVi1 and Vb in rabbit hearts subjected to ischemia/reperfusion

Autor: Narayan G. Avadhani, Haider Raza, Ji-Kang Fang, Naresh Babu V. Sepuri, Joseph F. Spear, Hindupur K. Anandatheerthavarada, Subbuswamy K. Prabu, Domenico F. Galati

Publikováno v: FEBS Letters. 581:1302-1310

We have mapped the sites of ischemia/reperfusion-induced phosphorylation of cytochrome c oxidase (CcO) subunits in rabbit hearts by using a combination of Blue Native gel/Tricine gel electrophoresis and nano-LC–MS/MS approaches. We used precursor i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1df486ff0964d9eec6e2a148d3eb62
https://doi.org/10.1016/j.febslet.2007.02.042

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Regulation of Murine Cytochrome c Oxidase Vb Gene Expression during Myogenesis

Autor: Frank Wilkinson, Ettickan Boopathi, Narayan G. Avadhani, Agata Giallongo, Nibedita Lenka, Subbuswamy K. Prabu, Ji-Kang Fang, Michael L. Atchison

Publikováno v: Journal of Biological Chemistry. 279:35242-35254

A transcription suppressor element (sequence -481 to -320) containing a G-rich motif (designated GTG) and a newly identified CAT-rich motif (designated CATR) was previously shown to modulate expression of the mouse cytochrome c oxidase Vb gene during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32d37b29cf07854fb803d7027e95e28d
https://doi.org/10.1074/jbc.m403160200

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Mitochondrial Targeted Cytochrome P450 2E1 (P450 MT5) Contains an Intact N Terminus and Requires Mitochondrial Specific Electron Transfer Proteins for Activity

Autor: Ji-Kang Fang, Mare Cudic, Marie-Anne Robin, Narayan G. Avadhani, Hindupur K. Anandatheerthavarada, Laszlo Otvos

Publikováno v: Journal of Biological Chemistry. 276:24680-24689

Hepatic mitochondria contain an inducible cytochrome P450, referred to as P450 MT5, which cross-reacts with antibodies to microsomal cytochrome P450 2E1. In the present study, we purified, partially sequenced, and determined enzymatic properties of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b765a12b859fac05b8254d5c56bd799a
https://doi.org/10.1074/jbc.m100363200

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Accumulation of Mitochondrial P450MT2, NH2-terminal Truncated Cytochrome P4501A1 in Rat Brain during Chronic Treatment with β-Naphthoflavone

Autor: Ettickan Boopathi, Hindupur K. Anandatheerthavarada, Shripad V. Bhagwat, Ji-Kang Fang, Narayan G. Avadhani, Gopa Biswas

Publikováno v: Journal of Biological Chemistry. 275:34415-34423

The biochemical and molecular characteristics of cytochrome P4501A1 targeted to rat brain mitochondria was studied to determine the generality of the targeting mechanism previously described for mitochondrial cytochrome P450MT2 (P450MT2) from rat liv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::346461a43af6d92c4024e2723f5c1f37
https://doi.org/10.1074/jbc.m004431200

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Purification and Characterization of a Hepatic Mitochondrial Glutathione-S-Transferase Exhibiting Immunochemical Relationship to the α-Class of Cytosolic Isoenzymes

Autor: Ji-Kang Fang, Narayan G. Avadhani, Sankar Addya, Jayati Mullick

Publikováno v: Archives of Biochemistry and Biophysics. 310:82-88

Hepatic mitochondria from different mammalian species contain varying levels of glutathione S-transferase (GST) activities. More than 70% of the activity detectable in the mouse liver mitochondria is associated with the soluble matrix. The mouse mito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46d73e1a7c8f3c8d605afdf7ccee77b
https://doi.org/10.1006/abbi.1994.1143

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