Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ji Hyun Oum"'
Autor:
Eun Yong Shim, Amy Sid, Anna Malkova, Ji Hyun Oum, Sang Eun Lee, Youngho Kwon, Grzegorz Ira, Changhyun Seong, Jae-Hoon Ji, Sreejith Ramakrishnan, Patrick Sung
Publikováno v:
Molecular and Cellular Biology. 31:3924-3937
Homologous recombination repairs DNA double-strand breaks by searching for, invading, and copying information from a homologous template, typically the homologous chromosome or sister chromatid. Tight wrapping of DNA around histone octamers, however,
The Yeast Chromatin Remodeler RSC Complex Facilitates End Joining Repair of DNA Double-Strand Breaks
Publikováno v:
Molecular and Cellular Biology. 25:3934-3944
Repair of chromosome double-strand breaks (DSBs) is central to cell survival and genome integrity. Nonhomologous end joining (NHEJ) is the major cellular repair pathway that eliminates chromosome DSBs. Here we report our genetic screen that identifie
Publikováno v:
Biochemical and Biophysical Research Communications. 298:486-492
NFAT (nuclear factor of activated T cells) plays a pivotal role in inducible gene transcription during the immune response and functions as a major target for immunosuppressive drugs such as cyclosporin A and FK-506. However, due to toxic effects of
Publikováno v:
European Journal of Biochemistry. 269:1162-1170
Retinoids are potent immune modulators that inhibit Fas ligand (FasL) expression and thereby repress the activation-induced apoptosis of immature thymocytes and T-cell hybridomas. In this study, we demonstrate that all-trans-retinoic acid (all-trans-
Publikováno v:
The FASEB Journal. 25
Autor:
Soma Banerjee, Sang Eun Lee, Nilabja Sikdar, Kyungjae Myung, Hungjiun Liaw, Stephanie Smith, Ji Hyun Oum, Akira Motegi, Ji-Young Hwang
Publikováno v:
The Journal of Cell Biology
Gross chromosomal rearrangement (GCR) is a type of genomic instability associated with many cancers. In yeast, multiple pathways cooperate to suppress GCR. In a screen for genes that promote GCR, we identified MPH1, which encodes a 3′–5′ DNA he
Publikováno v:
Molecular cell. 30(3)
Elimination of a double-strand break (DSB) flanked by direct repeat sequences is mediated by single-strand annealing (SSA), which relies on a distinct set of gene products involving recombination, mismatch repair, and nucleotide excision repair. Here
Autor:
Juhyun, Han, Minjung, Kim, Ji-Hyun, Oum, Heejoon, Myung, Seong-Wook, Lee, Sunjoo, Jeong, Surendra, Sharma, Jungchan, Park
Publikováno v:
Molecules and cells. 14(3)
To isolate and characterize a novel protein that interacts with nuclear factor of activated T cells (NFAT) and potentially regulates its activity, we screened a Jurkat cDNA library by using the NFAT regulatory domain as bait in the yeast two-hybrid s
Publikováno v:
Molecules and cells. 13(1)
Nuclear factor of activated T cells (NFAT) is a family of transcription factors that regulates activation-induced transcription of many immunologically important genes. Although all NFAT family proteins contain a highly conserved DNA-binding domain a
Publikováno v:
European journal of biochemistry. 269(4)
Retinoids are potent immune modulators that inhibit Fas ligand (FasL) expression and thereby repress the activation-induced apoptosis of immature thymocytes and T-cell hybridomas. In this study, we demonstrate that all-trans-retinoic acid (all-trans-