Ciliatoside A, isolated from Peristrophe japonica, inhibits HBsAg expression and cccDNA transcription by inducing autophagy.

Autor: Fang R; The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Sichuan-Chongqing Co-construction for Diagnosis and Treatment of Infectious Diseases Integrated Traditional Chinese and Western Medicine, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China., Ming T; The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Ng JPL; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau., An Guo W; Sichuan Key Medical Laboratory of New Drug Discovery and Drug Ability Evaluation, Key Laboratory of Medical Electrophysiology of Ministry of Education, School of Pharmacy, Southwest Medical University, Luzhou, China., Si Yu Y; The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Hui Z; The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Ji Hua R; The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Sheng Tao C; The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China., Juan Z; Chongqing Key Laboratory of Sichuan-Chongqing Co-construction for Diagnosis and Treatment of Infectious Diseases Integrated Traditional Chinese and Western Medicine, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China., Hang Hong L; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau., Wong VKW; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau. Electronic address: bowaiwong@gmail.com., Law BYK; Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau. Electronic address: yklaw@must.edu.mo., Juan C; The Key Laboratory of Molecular Biology of Infectious Diseases Designated By the Chinese Ministry of Education, Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China; Key Laboratory of Laboratory Medical Diagnostics, Chinese Ministry of Education, Chongqing Medical University, Chongqing, China. Electronic address: chenjuan2014@cqmu.edu.cn.

Publikováno v: Antiviral research [Antiviral Res] 2023 Jan; Vol. 209, pp. 105482. Date of Electronic Publication: 2022 Dec 07.

Cellular Id1 inhibits hepatitis B virus transcription by interacting with the novel covalently closed circular DNA-binding protein E2F4.

Autor: Jie Wei, Yueyuan Shi, Chunhong Zou, Hongpeng Zhang, Hui Peng, Shilei Wang, Lulu Xia, Yuan Yang, Xiang Zhang, Junye Liu, Hua Zhou, Miao Luo, Ailong Huang, Deqiang Wang

Publikováno v: International Journal of Biological Sciences; 2022, Vol. 18 Issue 1, p65-81, 17p