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Anti‐Warburg effect via generation of ROS and inhibition of PKM2 /β‐catenin mediates apoptosis of lambertianic acid in prostate cancer cells

Autor: Ji‐Na Pak, Hyo‐Jung Lee, Deok Yong Sim, Ji Eon Park, Chi‐Hoon Ahn, Su‐Yeon Park, Jae‐Ho Khil, Bumsang Shim, Bonglee Kim, Sung‐Hoon Kim

Publikováno v: Phytotherapy Research.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f8892154b9d5288adcff6705758f93f
https://doi.org/10.1002/ptr.7903

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Antitumor mechanism of combination of Angelica gigas and Torilis japonica in LNCaP prostate cancer cells via G1 arrest and inhibition of Wnt/β‐catenin and androgen receptor signaling

Autor: Dong Hee Kim, Eunji Im, Dae Young Lee, Hyo‐Jung Lee, Deok Yong Sim, Ji Eon Park, Chi‐Hoon Ahn, Ja Il Koo, Ji‐Na Pak, Sung‐Hoon Kim

Publikováno v: Phytotherapy Research. 36:2999-3008

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8adc462c1a94ed8fed0d48cd8d829d26
https://doi.org/10.1002/ptr.7494

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Antitumor mechanism of combination of Angelica gigas and Torilis japonica in LNCaP prostate cancer cells via G1 arrest and inhibition of Wnt/β-catenin and androgen receptor signaling

Autor: Dong Hee, Kim, Eunji, Im, Dae Young, Lee, Hyo-Jung, Lee, Deok Yong, Sim, Ji Eon, Park, Chi-Hoon, Ahn, Ja Il, Koo, Ji-Na, Pak, Sung-Hoon, Kim

Publikováno v: Phytotherapy research : PTRREFERENCES. 36(7)

The goal of the current study is to assess the antitumor mechanism by the combination (7:3) of Angelica gigas and Torilis japonica (AT) that was found most effective through screening against prostate-specific antigen (PSA) in LNCaP prostate cancer c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e52bdbe1f5b1f29e161e626b8e5237de
https://pubmed.ncbi.nlm.nih.gov/35634973

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Inhibition of TMPRSS4 mediated epithelial-mesenchymal transition is critically involved in antimetastatic effect of melatonin in colorectal cancers

Autor: Deok Yong Sim, Dong Hee Kim, Woon Yi Park, Youngsang Park, Hyo-Jung Lee, Bum Suk Oh, Sung-Hoon Kim, Jinsuk Koo, Bum Sang Shim, Ji Eon Park, Ji-Na Pak, Eunji Im

Publikováno v: Phytotherapy research : PTRREFERENCES. 35(8)

In the current study, the underlying anti-metastatic mechanism of melatonin contained in some edible plants was explored in association with transmembrane protease serine 4 (TMPRSS4) mediated metastasis and epithelial-mesenchymal transition (EMT) sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3800c4de4f07764ac5840d23901402f3
https://pubmed.ncbi.nlm.nih.gov/34114707

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p53 dependent LGR5 inhibition and caspase 3 activation are critically involved in apoptotic effect of compound K and its combination therapy potential in HCT116 cells

Autor: Ji Eon Park, Bumsang Shim, Hyo-Jung Lee, Ji Hoon Jung, Sung-Hoon Kim, Jisung Hwang, Ji-Na Pak

Publikováno v: Phytotherapy research : PTRREFERENCES. 34(10)

Though ginsenoside metabolite compound K was known to have antitumor effect in several cancers, its underlying apoptotic mechanism still remains unclear so far. Thus, in the present study, the apoptotic mechanism of compound K was explored in colorec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b2ff97291750b85914a233fef274c9
https://pubmed.ncbi.nlm.nih.gov/32403193

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Reactive Oxygen Species and p53 Mediated Activation of p38 and Caspases is Critically Involved in Kaempferol Induced Apoptosis in Colorectal Cancer Cells

Autor: Sung-Hoon Kim, Ji-Na Pak, Hyemin Lee, Bum Sang Shim, Jhin-Baek Choi, Ju-Ha Kim

Publikováno v: Journal of agricultural and food chemistry. 66(38)

Here the molecular mechanisms of Kaempferol were examined in colorectal cancers (CRCs). Kaempferol significantly exerted antiproliferative and cytotoxic effect in HCT116, HCT15, and SW480 cells. Also, Kaempferol increased sub G1 population, G2/M arre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f803912cc36eaacd93b32cbf5547b897
https://pubmed.ncbi.nlm.nih.gov/30211553

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