Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Ji‐Kyung Choi"'
Autor:
Derek J. Erstad, Christian T. Farrar, Sarani Ghoshal, Ricard Masia, Diego S. Ferreira, Yin‐Ching Iris Chen, Ji‐Kyung Choi, Lan Wei, Phillip A. Waghorn, Nicholas J. Rotile, Chuantao Tu, Katherine A. Graham‐O'Regan, Mozhdeh Sojoodi, Shen Li, Yang Li, Guogiang Wang, Kathleen E. Corey, Yat Sun Or, Lijuan Jiang, Kenneth K. Tanabe, Peter Caravan, Bryan C. Fuchs
Publikováno v:
Hepatology Communications, Vol 2, Iss 7, Pp 821-835 (2018)
We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. We used molecular magnetic reso
Externí odkaz:
https://doaj.org/article/3b4760b0fefd4d1697564907fb1c9f1f
Autor:
Arnar Astradsson, Bruce G. Jenkins, Ji-Kyung Choi, Penelope J. Hallett, Michele A. Levesque, Jack S. McDowell, Anna-Liisa Brownell, Roger D. Spealman, Ole Isacson
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 3, Pp 348-351 (2009)
It has been suggested, based on rodent studies, that levodopa (l-dopa) induced dyskinesia is associated with a disrupted blood–brain barrier (BBB). We have investigated BBB integrity with in vivo neuroimaging techniques in six 1-methyl-4-phenyl-1,2
Externí odkaz:
https://doaj.org/article/a2687b2f0be24c018642711d7c1a614e
Publikováno v:
Neurobiology of Disease, Vol 27, Iss 2, Pp 220-227 (2007)
A growing body of evidence indicates a role for D3 receptors in l-DOPA-induced dyskinesias. This involvement could be amenable to non-invasive in vivo analysis using functional neuroimaging. With this goal, we examined the hemodynamic response to the
Externí odkaz:
https://doaj.org/article/3a3ed7ca5d29453e95a6a76b623a2825
Autor:
Dany Arsenault, Katherine Coulombe, Aijun Zhu, Chunyu Gong, Kun-Eek Kil, Ji-Kyung Choi, Pekka Poutiainen, Anna-Liisa Brownell
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142093 (2015)
Parental microglial induced neuroinflammation, triggered by bacterial- or viral infections, can induce neuropsychiatric disorders like schizophrenia and autism to offspring in animal models. Recent investigations suggest that microglia, the resident
Externí odkaz:
https://doaj.org/article/fdbccad48b534a6bb5844e49177ec34a
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 7, Pp 1000-1010 (2002)
The remarkable binding properties of serum albumin have been investigated extensively, but little is known about an important class of fatty acids, the very long-chain saturated fatty acids (VLCFA; >18 carbons). Although VLCFA are metabolized efficie
Externí odkaz:
https://doaj.org/article/d842202f4b794efcb2c4eb5b90dda77a
Publikováno v:
Journal of Social Science. 31:191-207
최근 이슈인 코로나-19(COVID-19), 메르스(MERS-CoV) 등과 같은 전염병은 ‘국제적 공중보건 비상사태(PHEIC)’를 선포하며 국제적인 대응과 다차원적인 접근을 요구하고 있다. 재난발생 시 사회복
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0df1aea15dd75510655864726232db
https://doi.org/10.16881/jss.2020.07.31.3.191
https://doi.org/10.16881/jss.2020.07.31.3.191
Autor:
Timothy M. Shoup, Chuzhi Pan, Ji-Kyung Choi, Sepideh Afshar, Junfeng Wang, Aijun Zhu, Xiying Qu, Hye Jin Kang, Pekka Poutiainen, Zhaoda Zhang, Anna-Liisa Brownell, Georges El Fakhri, Gengyang Yuan
Publikováno v:
Journal of Medicinal Chemistry. 63:3381-3389
We have synthesized and characterized [18F]-N-(4-chloro-3-((fluoromethyl-d2)thio)phenyl)-picolinamide ([18F]15) as a potential ligand for the positron emission tomography (PET) imaging of mGluR4 in the brain. Radioligand [18F]15 displays central nerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b66cfdecbcbb01348dc3d7f53268e98d
https://doi.org/10.1021/acs.jmedchem.0c00201
https://doi.org/10.1021/acs.jmedchem.0c00201
Autor:
David Izquierdo-Garcia, Himashinie Diyabalanage, Ian A. Ramsay, Nicholas J. Rotile, Adam Mauskapf, Ji-Kyung Choi, Thomas Witzel, Valerie Humblet, Farouc A. Jaffer, Anna-Liisa Brownell, Ahmed Tawakol, Ciprian Catana, Mark F. Conrad, Peter Caravan, Ilknur Ay
Publikováno v:
Stroke
Background and Purpose: High-risk atherosclerosis is an underlying cause of cardiovascular events, yet identifying the specific patient population at immediate risk is still challenging. Here, we used a rabbit model of atherosclerotic plaque rupture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdd6e940260615cf735eea871e8983d
https://europepmc.org/articles/PMC8792326/
https://europepmc.org/articles/PMC8792326/
Autor:
Ji-Kyung Choi, Isabel Carreras, Nurgul Aytan, Bruce G. Jenkins, Alpaslan Dedeoglu, Christina M. Tognoni, Neil W. Kowall
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Lipid metabolism is abnormal in Alzheimer’s disease (AD) brain leading to ceramide and sphingosine accumulation and reduced levels of brain sphingosine-1-phosphate (S1P). We hypothesize that changes in S1P signaling are central to the inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46eff66e37647f87c0dbaa6e0c03b1b
http://link.springer.com/article/10.1038/s41598-019-47287-1
http://link.springer.com/article/10.1038/s41598-019-47287-1
Autor:
Junfeng, Wang, Xiying, Qu, Timothy M, Shoup, Gengyang, Yuan, Sepideh, Afshar, Chuzhi, Pan, Aijun, Zhu, Ji-Kyung, Choi, Hye Jin, Kang, Pekka, Poutiainen, Georges, El Fakhri, Zhaoda, Zhang, Anna-Liisa, Brownell
Publikováno v:
J Med Chem
We have synthesized and characterized [(18)F]-N-(4-chloro-3-((fluoromethyl-d(2))thio)phenyl)-picolinamide ([(18)F]15) as a potential ligand for the PET imaging of mGluR4 in the brain. Radioligand [(18)F]15 displays CNS drug-like properties, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::932117195d0ab9ef9afcd55cf83a1d9b
https://pubmed.ncbi.nlm.nih.gov/32081008
https://pubmed.ncbi.nlm.nih.gov/32081008