Výsledky vyhledávání - "Jiřina Chládková"

No Effect of Phenobarbital Pretreatment of Rats on Methotrexate Pharmacokinetics in the Isolated Liver Perfused in a Single-Pass Way

Autor: Martínková J, Jiřina Chládková, Luděk Šišpera, Jaroslav Chládek, Jolana Cermanova

Publikováno v: Pharmacology. 62:92-97

Pretreatment of the rat with phenobarbital (PB) is known to increase gene expression of the canalicular multispecific organic anion transporter (cMOAT) and hepatobiliary transport of its substrates (glutathione, sulfobromophthalein). To determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0ad90e5e55826f9f49e6b564c231f1
https://doi.org/10.1159/000056077

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High-dose methotrexate in children with acute lymphoblastic leukemia: 7-hydroxymethotrexate systemic exposure and urinary concentrations at the steady state correlate well with those of methotrexate

Autor: Martínková J, Jaroslav Chládek, Jiří Hak, Jiřina Chládková

Publikováno v: ResearcherID

The present study evaluated the pharmacokinetics of methotrexate (MTX, CAS 59-05-2) and 7-hydroxymethotrexate (7-OHMTX, CAS 5939-37-7) in children with acute lymphoblastic leukemia (ALL) with particular interest devoted to the renal excretion at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9daa85d0decb7dd1b7eeb4ceb6b0a7
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000285797400005&KeyUID=WOS:000285797400005

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