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pro vyhledávání: '"Jiřina Borovská"'
Publikováno v:
Collection of Czechoslovak Chemical Communications. 76:1141-1161
We have prepared 20-oxo-5α- and 20-oxo-5β-pregnane-3-carboxylic acids by palladium catalyzed alkoxycarbonylation using triflate and nonaflate as the leaving groups in this substitution reaction. The activity of the synthesized compounds was studied
Autor:
Vladimír Pouzar, Hana Chodounska, Ladislav Vyklický, Ivan Černý, Jiřina Borovská, Vojtěch Vyklický, Lukáš Vidrna
Publikováno v:
Steroids. 76(10-11)
Analogs of pregnanolone (3α-hydroxy-5β-pregnan-20-one), modified in position 17 were prepared. Compounds with 20-keto pregnane side chain replaced completely by azide (17α- and 17β-azido-5β-androstan-3α-ol), compounds with its part replaced (20