Thermoresponsive poly(2-oxazoline) homopolymers and copolymers in aqueous solutions studied by NMR spectroscopy and dynamic light scattering

Autor: Jiří Spěváček, Peter Černoch, Rafał Konefał

Publikováno v: European Polymer Journal. 100:241-252

Structural changes during temperature-induced phase transition in D2O solutions of poly(2-ethyl-2-oxazoline) (PEOx) and P(EOx-grad-2-methyl-2-oxazoline (MOx)) copolymers were investigated by 1H NMR methods in combination with dynamic light scattering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f68db2a9557e3f043cd847a73238674
https://doi.org/10.1016/j.eurpolymj.2018.01.019

One-pot synthesis of reactive oxygen species (ROS)-self-immolative polyoxalate prodrug nanoparticles for hormone dependent cancer therapy with minimized side effects

Autor: Yaming Jiang, Anita Höcherl, Martin Hrubý, Timothy P. Lodge, Rafał Konefał, Petr Štěpánek, Olga Janoušková, Peter W. Schmidt, Eliézer Jäger, Jiří Spěváček, Alessandro Jäger

Publikováno v: Polymer Chemistry. 8:1999-2004

A new reactive oxygen species (ROS)-sensitive, self-immolative biodegradable polyoxalate prodrug based on the anticancer chemotherapeutic hormone analog diethylstilbestrol was synthesized via one-pot step-growth polymerization. The nanoparticles prep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22ec33d63d0c5f91984350ddb424d608
https://doi.org/10.1039/c7py00270j

NMR Study of Thermoresponsive Block Copolymer in Aqueous Solution

Autor: Jiří Spěváček, Rafał Konefał, Eva Čadová

Publikováno v: Macromolecular Chemistry and Physics. 217:1370-1375

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c91e09db1d6e07cd3d6085ed30edbe4
https://doi.org/10.1002/macp.201600025

Thermoresponsive behavior of poly(DEGMA)-based copolymers. NMR and dynamic light scattering study of aqueous solutions

Autor: Richard Laga, Gabriela Mužíková, Jiří Spěváček, Rafał Konefał

Publikováno v: European Polymer Journal. 124:109488

We studied temperature behavior of diblock copolymers of poly[2-(2-methoxyethoxy)ethyl methacrylate] (PDEGMA) with poly(N-(2-hydroxypropyl)methacrylamide and a statistical copolymer PDEGMA-co-N-propargylmethacrylamide in aqueous solutions. NMR spectr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f1cbf052e8472d418c0964f56420ec3
https://doi.org/10.1016/j.eurpolymj.2020.109488

Structural changes on polymeric nanoparticles induced by hydrophobic drug entrapment

Autor: Frédéric Nallet, Eliézer Jäger, Alessandro Jäger, Petr Štěpánek, Jiří Spěváček, Fernando C. Giacomelli, Jean-Luc Putaux, Rafał Konefał, Karel Ulbrich, Milos Steinhart

Publikováno v: Colloids and Surfaces A: Physicochemical and Engineering Aspects
Colloids and Surfaces A: Physicochemical and Engineering Aspects, Elsevier, 2018, 538, pp.238-249. ⟨10.1016/j.colsurfa.2017.10.059⟩

The potential use of polyester polymeric nanoparticles (NPs) as drug nanocarriers is well-documented. Nevertheless, structural changes due to hydrophobic drug loading and release have been rarely explored. Herein, we have used static and dynamic ligh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e524e29d60ebd5eb0401f9415639e8d4
https://hal.archives-ouvertes.fr/hal-02106167