THE ROLE OF GABAB REGULATORY PROTEIN KCTD16 IN PAIN MODULATION

Autor: Daniel Vasconcelos, Mario Heles, Pavel Adamek, Jiří Paleček

Publikováno v: IBRO Neuroscience Reports, Vol 15, Iss , Pp S723- (2023)

Externí odkaz: https://doaj.org/article/4114d8d59fee4e168e2fb48dcfe372f2

Dual effect of anandamide on spinal nociceptive transmission in control and inflammatory conditions

Autor: Monica Pontearso, Jakub Slepicka, Anirban Bhattacharyya, Diana Spicarova, Jiri Palecek

Publikováno v: Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116369- (2024)

Anandamide (AEA) is an important modulator of nociception in the spinal dorsal horn, acting presynaptically through Cannabinoid (CB1) and Transient receptor potential vanilloid (TRPV1) receptors. The role of AEA (1 µM, 10 µM, and 30 µM) applicatio

Externí odkaz: https://doaj.org/article/e995daf0ac7746bea8bdb79633ddf24c

Towards a biocompatible artificial lung: Covalent functionalization of poly(4-methylpent-1-ene) (TPX) with cRGD pentapeptide

Autor: Christian Hess, Gerald Dräger, Axel Haverich, Lena Möller, Andreas Kirschning, Jiří Paleček, Yi Su

Publikováno v: Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 270-277 (2013)
Beilstein Journal of Organic Chemistry 9 (2013)

Covalent multistep coating of poly(methylpentene), the membrane material in lung ventilators, by using a copper-free "click" approach with a modified cyclic RGD peptide, leads to a highly biocompatible poly(methylpentene) surface. The resulting modif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aadbcdc66a5dc92c32a5e46c59b1574
http://europepmc.org/articles/PMC3596089

Inhibition of synaptic transmission by anandamide precursor 20:4-NAPE is mediated by TRPV1 receptors under inflammatory conditions

Autor: Diana Spicarova, Vladimir Nerandzic, David Muzik, Monica Pontearso, Anirban Bhattacharyya, Istvan Nagy, Jiri Palecek

Publikováno v: Frontiers in Molecular Neuroscience, Vol 16 (2023)

Transient receptor potential ion channel, vanilloid subfamily, type 1 (TRPV1) cation channel, and cannabinoid receptor 1 (CB1) are essential in the modulation of nociceptive signaling in the spinal cord dorsal horn that underlies different pathologic

Externí odkaz: https://doaj.org/article/b73cfc7f318741579b788d9e0298b8c7

Long term expansion of undifferentiated human iPS and ES cells in suspension culture using a defined medium

Autor: Wei Cui, Jiří Paleček, Ulrich Martin, Sylvia Merkert, Andreas Kirschning, Eric Hayes, Konstantin Miller, Ruth Olmer, Thomas Scheper, Chen Ran, Alexandra Haase, Eliza Curnow, Silke Glage

Publikováno v: Stem Cell Research. 5(1):51-64

Therapeutic application of stem cell derivatives requires large quantities of cells produced in defined media that cannot be produced via conventional adherent culture. We have applied human induced pluripotent stem (hiPS) cells expressing eGFP under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b00ef49ffa27a04eacb4a638389900